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How coronavirus tests work

Video from Nova on how the tests work.

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Lisa Scheifele onto Coronavirus

ISCB Education and Training Resources

Our Vision is to see high quality computational biology education and training accessible to all interested communities across the world, and instilled in all life science-related educational programs.

Our Mission is to promote worldwide education and training in computational biology by providing guidance and support for educational resources and community activities.

The information contained within this section covers two general areas:

  1. World-wide educational and training resources for all levels from novices to advanced practitioners of computational biology
  2. Resources that enhance learning and preparation geared towards a career in computational biology

In addition to the content generated by ISCB Education, we also solicit and collect input and information from the larger computational biology community to be made available through these pages.

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The Jackson Laboratory Courses and Workshops

The Genomic Education team at The Jackson Laboratory is committed to creating diverse and inclusive educational programs where all students, employees and visitors feel valued and are empowered to participate in our mission to improve human health though genomics research, scientific resources and education. We believe human diversity is an essential ingredient for empowering the global biomedical community, and therefore our programs should reflect, embrace and celebrate the diversity of our world ... JAX's programs for high school and undergraduate students and teachers predate the founding of the Jackson Laboratory by six years. Including our flagship Summer Student Program, JAX offers opportunities for academic year research, teacher professional development, and the Maine State Science Fair.

Courses are designed to impart knowledge through intensive lectures, hands-on training and informal interactions. Workshops offer extensive hands-on training, teaching participants how to perform specific techniques, interspersed with lectures or seminars.

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GOBLET

This portal allows you to browse our course pages and training materials, to download content of interest and/or to upload course pages and training materials.

NOTE: this page has not been updated for more than 4 months.

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Galaxy Training Materials

This web site is a gateway for lessons, tutorial, and examples of using Galaxy for genomics education and analysis. Among other things, links to tutorials for the following subjects are provided:


Events with Galaxy-related content (includes virtual events)

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Assignment for Coronavirus dianostic kit design

The homework assigned through the files follows a presentation on qPCR. The goal of the assignment is for the students to get primer pairs that do not bind to human DNA or the SARS Coronavirus that caused the 2003 epidemic. It is easy to assess through Primer-Blast or the UCSC in-silico PCR tool (links provided above).

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Nik Tsotakos onto Coronavirus

In-classroom activity for genome alignment of different strains of viruses in the Coronaviridae family

This is an activity that took place in an Advanced Genetics class that meets in a computer lab. The activity aims to construct a phylogenetic tree of different Coronaviruses, including a few strains of SARS-CoV2. The sequences were pulled from the Virus Pathogen Database and Genbank. Since the activity initially took place in mid-February, there are a lot more available sequences in the databases, while at least one of the sequences included has been retracted. The homework in the end is another application of the skillset the students acquired through the activity, and can be modified based on the course's objectives.

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Nik Tsotakos onto Coronavirus

Cases from the National Center for Case Study Teaching in Science

NCCSTS requires a $25 annual subscription for individuals.  Materials are peer reviewed, and include student handouts and teacher materials.  We are sharing information about recent cases published on COVID19 from this organization:

"COVID-19: Where Did You Come From, Where Did You Go?” by authors from North Carolina State University: Stefanie H. Chen, Carlos C. Goller, and Melissa C. Srougi

https://sciencecases.lib.buffalo.edu/collection/detail.html?case_id=1125&id=1125

"Put to the Test: RT-PCR and Antibody Detection Diagnostic Tools for COVID-19 ” by a team of authors from Brandeis University:  Melissa S. Kosinski-Collins, Lindsay Mehrmanesh, Jessie Cuomo and Kene N. Piasta.

Fatally Flawed? Early Genetic Testing for the COVID-19 Virus” by Amy C. Groth, Department of Biology, Eastern Connecticut State University

https://sciencecases.lib.buffalo.edu/collection/detail.html?case_id=1123&id=1123

Social Distancing in the Midst of COVID-19” is by Jason C. Cochrane, Science Department, Mountain Vista High School, Highlands Ranch, CO. 

https://sciencecases.lib.buffalo.edu/collection/detail.html?case_id=1113&id=1113

 “Pandemic Pandemonium: Why Can’t We Just Treat COVID-19?” by a team of authors from Brandeis University:  Melissa S. Kosinski-Collins, Lindsay Mehrmanesh, Jessie Cuomo and Kene N. Piasta.

https://sciencecases.lib.buffalo.edu/collection/detail.html?case_id=1114&id=1114 

"Coronavirus Quandaries for Patients with Cardiovascular Disease” by Janine Bartholomew, Department of Biology, Carlow University, Pittsburgh, PA

https://sciencecases.lib.buffalo.edu/collection/detail.html?case_id=1121&id=1121

Where’s the Evidence? Confronting Public Panic About COVID-19” by Laura Pickell, Department of Biology, Cégep Heritage College, Gatineau, QC, Canada

https://sciencecases.lib.buffalo.edu/collection/detail.html?case_id=1120&id=1120

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Kristin Jenkins onto COVID-19/Public Health

Teaching Effectively Online from CIRTL

The CIRTL Network is providing various trainings to assist in the sudden transition to online learning as campuses close to slow the spread of COVID-19. These trainings are offered both as synchronous online workshops and in recorded modules on YouTube.

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How UDL Can Support Your Transition to Online Teaching

Crowd-sourced table of online teaching practices that align to the UDL guidelines specific to the affective network

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Synthetic Organisms Simplify Biology

Review article from 2019

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Lisa Scheifele onto Creating synthetic genomes

A semi-synthetic organism that stores and retrieves increased genetic information

Creation of a semi-synthetic organism whose DNA harbours two additional letters that form a third, unnatural base pair.

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Lisa Scheifele onto Creating synthetic genomes

Genome-wide inactivation of Retroviruses

Demonstration of inactivation of porcine endogenous retroviruses using CRISPR technology to enable porcine-to-human xenotransplantation of organs.

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Lisa Scheifele onto Creating synthetic genomes

Engineering bacteria for diagnostic and therapeutic applications

A review article on designing bacteria for diagnostics and therapeutics

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Lisa Scheifele onto Creating synthetic genomes

Total synthesis of Escherichia coli with a recoded genome

A synthetic E. coli genome that has been designed to use only 61 of the 64 available codons. Includes webinar from Genewiz on design and assembly of the genome.

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Lisa Scheifele onto Creating synthetic genomes

Technological challenges and milestones for writing genomes

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Lisa Scheifele onto Creating synthetic genomes

Synthetic Generation of Influenza Vaccine Viruses for Rapid Response to Pandemics

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Lisa Scheifele onto Creating synthetic genomes

Synthetic Reconstruction of Zoonotic and Early Human Severe Acute Respiratory Syndrome Coronavirus Isolates That Produce Fatal Disease in Aged Mice

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Lisa Scheifele onto Coronavirus

Standard and AEGIS nicking molecular beacons detect amplicons fromthe Middle East respiratory syndrome coronavirus

Use of synthetic biology to improve the signal-to-noise ratio in coronavirus diagnostics

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Lisa Scheifele onto Coronavirus