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Genome-wide inactivation of Retroviruses

Demonstration of inactivation of porcine endogenous retroviruses using CRISPR technology to enable porcine-to-human xenotransplantation of organs.

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Lisa Scheifele onto Creating synthetic genomes

Engineering bacteria for diagnostic and therapeutic applications

A review article on designing bacteria for diagnostics and therapeutics

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Lisa Scheifele onto Creating synthetic genomes

Total synthesis of Escherichia coli with a recoded genome

A synthetic E. coli genome that has been designed to use only 61 of the 64 available codons. Includes webinar from Genewiz on design and assembly of the genome.

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Lisa Scheifele onto Creating synthetic genomes

Technological challenges and milestones for writing genomes

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Lisa Scheifele onto Creating synthetic genomes

Synthetic Generation of Influenza Vaccine Viruses for Rapid Response to Pandemics

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Profile picture of Lisa Scheifele

Lisa Scheifele onto Creating synthetic genomes

Synthetic Reconstruction of Zoonotic and Early Human Severe Acute Respiratory Syndrome Coronavirus Isolates That Produce Fatal Disease in Aged Mice

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Lisa Scheifele onto Coronavirus

Standard and AEGIS nicking molecular beacons detect amplicons fromthe Middle East respiratory syndrome coronavirus

Use of synthetic biology to improve the signal-to-noise ratio in coronavirus diagnostics

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Lisa Scheifele onto Coronavirus

Should scientists infect healthy people with the coronavirus to test vaccines?

Perspectives article discussing important ethical dilemmas in developing coronavirus vaccines.

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Lisa Scheifele onto Coronavirus

Rapid reconstruction of SARS-CoV-2 using a synthetic genomics platform

Use of synthetic genomics to clone and synthesize the Covid-19 genome. Preprint from Biorxiv.

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Lisa Scheifele onto Coronavirus

Race to find COVID-19 treatments accelerates

Review article on different potential treatment strategies and where in the viral life cycle intervention is possible.

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Lisa Scheifele onto Coronavirus

Mechanisms of Zoonotic Severe Acute Respiratory Syndrome Coronavirus Host Range Expansion in Human Airway Epithelium

Using synthetic biology, the authors engineered the spike protein (S) from an animal strain and used in vitro evolution to understand how it could adapt to replicate well in human cells.

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Lisa Scheifele onto Coronavirus

Identifying SARS-CoV-2 related coronaviruses in Malayan pangolins

One of the first papers sequencing Covid-19 viruses and identifying its potential animal source

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Lisa Scheifele onto Coronavirus

Identification of the Mechanisms Causing Reversion to Virulence in an Attenuated SARS-CoV for the Design of a Genetically Stable Vaccine

Paper investigating the development of safe and effective vaccines against SARS coronavirus

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Lisa Scheifele onto Coronavirus

Simulator for the spread of coronavirus

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Lisa Scheifele onto Coronavirus

What This Chart Actually Means for COVID-19

A video from PBS's It's Okay to Be Smart explaining the spread of coronaviruses, social distancing, and what it means to "flatten the curve"

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Lisa Scheifele onto Coronavirus

Exponential growth and epidemics

Highly useful explainer video on exponential growth and its contribution to epidemics

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Lisa Scheifele onto Coronavirus

Dr. Anthony Fauci on the Daily Show

Accurate answers to common questions about coronavirus

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Lisa Scheifele onto Coronavirus

Detecting respiratory viral RNA using expanded genetic alphabets and self-avoiding DNA

Improved methods to detect multiple respiratory viruses with one very specific assay

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Lisa Scheifele onto Coronavirus

MAA Emergency Online Teaching Toolkit

This Google doc has an abundance of tools, video tips, and information about how to transition to emergency teaching online.

MAA is the Mathematical Association of America and is the professional society in the US devoted primarily to the support of faculty for undergraduate instruction.

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Carrie Diaz Eaton onto Tools for teaching remotely

Fred Hutch's List of science papers to read about the coronavirus

Fred Hutchinson Cancer Research Center's list of science papers you should be reading about the coronavirus: Amid the thousands of research publications on COVID-19, here are the ones they are reading

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Kristine Grayson onto COVID-19/Public Health

SEIR on networks with Github and Tweet thread

This is a python package for exploring SEIR models on social networks. The first link is to a Twitter thread where the use and some significant results are explained.

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Carrie Diaz Eaton onto COVID-19/Public Health

Dr. Kestler’s Coronavirus Video Series

Dr. Harry Kestler at LCCC keeps us informed about the coronavirus and how we can all work together to slow the spread of COVID-19 in this series of daily videos about various aspects of the pandemic: https://www.lorainccc.edu/security/dr-kestlers-coronavirus-video-series/

Prior to his position at LCCC, Kestler held faculty positions at the Lerner Medical College of the Cleveland Clinic and the department of Microbiology and Molecular Genetics at Harvard Medical School.

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Kristin Jenkins onto COVID-19/Public Health

Post Test 1

Testing 3

 

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Nathan Snodgrass onto Test 3

Post Test 3

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Nathan Snodgrass onto Test 2