CourseSource: Resources

Lesson

4699

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465

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Does Organelle Shape Matter?: Exploring Patterns in Cell Shape and Structure with High-Throughput (HT) Imaging

Organelle structure has been studied and visualized for decades; however, publicly available databases that use improved high-throughput microscopy of gene-edited cell lines have recently revolutionized the amount and quality of information now...

Courses: Biochemistry and Molecular Biology Bioinformatics Cell Biology Genetics Science Process Skills

modelingcase studymicroscopystructureOrganellesHigh-throughput (HT)Endoplasmic Reticulum (ER)Fluorescent microscopyHuman Cell Biology

Lesson

4819

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884

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0

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Tackling "Big Data" with Biology Undergrads: A Simple RNA-seq Data Analysis Tutorial Using Galaxy

Analyzing high-throughput DNA sequence data is a fundamental skill in modern biology. However, real and perceived barriers such as massive file sizes, substantial computational requirements, and lack of instructor background knowledge can...

Courses: Biochemistry and Molecular Biology Bioinformatics

bioinformaticsDNA sequenceRNAseqgene expression

Lesson

6430

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1613

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0

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Single Cell Insights Into Cancer Transcriptomes: A Five-Part Single-Cell RNAseq Case Study Lesson

There is a growing need for integration of “Big Data” into undergraduate biology curricula. Transcriptomics is one venue to examine biology from an informatics perspective. RNA sequencing has largely replaced the use of microarrays for whole...

Courses: Biochemistry and Molecular Biology Bioinformatics Cell Biology Genetics Introductory Biology

bioinformaticscancertranscriptomicshigh-throughputData wranglingSingle cell RNA sequencingq

Lesson

1459

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288

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0

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Using QIIME to Interpret Environmental Microbial Communities in an Upper Level Metagenomics Course

Metagenomics is rapidly evolving due to advances in sequencing technologies and bioinformatics, but without proper training to interpret these datasets, student understanding remains limited. Aimed at undergraduate juniors and seniors and graduate...

Courses: Biochemistry and Molecular Biology Bioinformatics Ecology Ecology Microbiology Science Process Skills

microbiome

Lesson

378

views

43

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0

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Using Raw Sequence Data to Analyze Tumor Suppressor Mutations

Learning to identify DNA sequence variants from raw sequencing data (electropherograms) is a basic molecular biology skill with applications to basic research and clinical practice. Yet learning to map DNA sequence variants to functional regions...

Courses: Bioinformatics Genetics

bioinformaticsmutationDNAgenomic visualizationparts of a geneclinical consequencesraw data

Lesson

7706

views

379

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0

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Investigating Cell Signaling with Gene Expression Datasets

Modern molecular biology is a data- and computationally-intensive field with few instructional resources for introducing undergraduate students to the requisite skills and techniques for analyzing large data sets. This Lesson helps students: (i)...

Courses: Biochemistry and Molecular Biology Cell Biology

genomicstranscriptionsignaling

Lesson

4096

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277

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0

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Analysis of Microbiomes Using Free Web-Based Tools in Online and In-Person Undergraduate Science Courses

Our understanding of microbiomes, or the collection of microorganisms and their genes in a given environment, has been revolutionized by technological and computational advances. However, many undergraduate students do not get hands-on experiences...

Courses: Bioinformatics Ecology Ecology Microbiology

microbiomeDNA SubwayCyVerseCourse based undergraduate researchQIIME2ranacapa

Teaching Tools and Strategies

2084

views

337

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0

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DNA Detective: Genotype to Phenotype. A Bioinformatics Workshop for Middle School to College.

Advances in high-throughput techniques have resulted in a rising demand for scientists with basic bioinformatics skills as well as workshops and curricula that teach students bioinformatics concepts. DNA Detective is a workshop we designed to...

Courses: Biochemistry and Molecular Biology Bioinformatics Genetics Plant Biology

geneticsbioinformaticsDNAgenotypephenotypegenegene annotation

Lesson

1127

views

155

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0

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Central Dogma, Dictionaries, and Functions: Using Programming Concepts to Simulate Biological Processes

Technologies like next-generation sequencing, proteomics, and high-throughput phenotyping have transformed the way we do biology. There is a continued need for scientists with computational skills to analyze biological data while understanding the...

Courses: Bioinformatics

computationpythonJupyter notebookFunctionscentral dogmaDictionaries

Lesson

2063

views

293

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0

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Learning R for Biologists: A Mini Course Grab-Bag for Instructors

As biology becomes more data driven, teaching students data literacy skills has become central to biology curriculum. Despite a wealth of online resources that teach researchers how to use R, there are few that offer practical laboratory-based...

Courses: Anatomy-Physiology Bioinformatics Ecology Ecology Genetics

Rdata analysisRStudio

Lesson

2577

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413

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0

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An Introduction to Eukaryotic Genome Analysis in Non-model Species for Undergraduates: A tutorial from the Genome Consortium for Active Teaching

Advances in Next Generation Sequencing (NGS) technology have led to development of many research methods for analyzing genomic data. Students studying biology at the undergraduate level must hone their skills at genomic analysis to participate in...

Courses: Bioinformatics Genetics Science Process Skills

Speciationgenome evolutiongenetic variation

Lesson

5916

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1180

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0

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A CURE for Salmonella: A Laboratory Course in Pathogen Microbiology and Genomics

Rapid advances in genomics and bioinformatics, the vast amount of data generated by next-generation sequencing, and the penetration of the ‘-omics’ into many areas of biology have created a need for students with hands-on experience with...

Courses: Biochemistry and Molecular Biology Bioinformatics Ecology Ecology Microbiology

epidemiologyresearchbioinformaticsgenomicspublic healthAntibiotic Resistant BacteriaSalmonellaDNA sequencingpathogenic bacteria

Lesson

2018

views

639

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1

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Sequence Similarity: An inquiry based and "under the hood" approach for incorporating molecular sequence alignment in introductory undergraduate biology courses

Introductory bioinformatics exercises often walk students through the use of computational tools, but often provide little understanding of what a computational tool does "under the hood." A solid understanding of how a bioinformatics...

Courses: Biochemistry and Molecular Biology Bioinformatics Introductory Biology

BLASTmultiple sequence alignmentsequence similarityphylogramZika virusAlgorithmScoring Matrix

Lesson

18644

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396

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0

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A flexible, multi-week approach to plant biology - How will plants respond to higher levels of CO₂?

To help introductory biology students understand how plants will respond to higher levels of CO2, we have created a multi-week module consisting of a series of four related laboratory lessons. These lessons allow students to make connections among...

Courses: Introductory Biology Plant Biology

statisticsplantsphotosynthesiscarbon dioxidecommunicating sciencegroup workResource AllocationRespirationStomata

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1233

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21

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0

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Leveraging Panel Discussions to Promote Positive Representation, Develop Science Identity, and Shift Stereotypes

The overrepresentation of cis straight white male scientists in examples used in Biology curriculum makes it difficult for students with other axes of diversity (race/ethnicity, gender, sexuality, first-generation college-going, socioeconomic...

Courses: Professional Development and Career Planning

professional developmentEquitydiversityscience identitysense of belongingCentering Student VoicesCareer Paneland InclusionPositive Representation of Diverse ScientistsFostering Community Between Students

Lesson

4366

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1231

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Dilution and Pipetting Lesson Using Food Dyes

In this lesson students learn how to use micropipettors to accurately measure small volumes of liquids and perform dilutions using food dyes. Students dilute four food dyes at 10X concentration to 1X working stocks. Using the formula c1v1=c2v2...

Courses: Science Process Skills

dilutionCalculationLab SkillsMicropipetting

Teaching Tools and Strategies

3250

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119

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0

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Enhancing the Microscopy Skills of Non-Science Majors and Nursing Microbiology Students: Promoting the Practice of Observing Multiple Fields of View Using Blood Smear Slides

One of the challenges in teaching microscopy is having students scan multiple fields of view at high power magnification. Many times, students will feel this unnecessary, especially when presented with slides that show only one structure or a...

Courses: Introductory Biology Microbiology

Microscopy SkillsBlood SmearsBlood Disorders

Lesson

2689

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487

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0

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An Original-Design Board Game to Increase Student Comprehension of Cellular Respiration Pathways

Cellular respiration is a daunting topic for many students in introductory biology courses. Students are challenged at conceptual and factual levels, since instruction covers multiple metabolic pathways occurring across different cellular...

Courses: Biochemistry and Molecular Biology Cell Biology Introductory Biology Science Process Skills

GlycolysisCellular RespirationFermentationKrebs CycleOxidative phosphorylationpyruvate oxidation

Science Behind the Lesson

1343

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186

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The Science Behind the ACTN3 Polymorphism

A common polymorphism in the alpha-actinin-3 (ACTN3) gene results in the lack of ACTN3 protein expression in fast twitch muscle fibers in ~16% of the human population (1). This genetic change has been linked with muscle performance in humans (2)...

Courses: Anatomy-Physiology Genetics

protein structure and functionhuman genetic variationskeletal muscle physiology

Teaching Tools and Strategies

1203

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171

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0

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Facilitating Scientific Literacy Through Writing: A Write-to-Learn Assignment for Large Introductory Undergraduate Biology Courses

Write-to-learn (WTL) assignments have been used in a variety of disciplines to encourage conceptual learning and critical thinking in undergraduate education. These assignments focus on facilitating rather than assessing learning. Conversely,...

Courses: Introductory Biology

geneticsEvolutionecologyCellsPlants form and functionAnimals form and function

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Does Organelle Shape Matter?: Exploring Patterns in Cell Shape and Structure with High-Throughput (HT) Imaging

Tackling "Big Data" with Biology Undergrads: A Simple RNA-seq Data Analysis Tutorial Using Galaxy

Single Cell Insights Into Cancer Transcriptomes: A Five-Part Single-Cell RNAseq Case Study Lesson

Using QIIME to Interpret Environmental Microbial Communities in an Upper Level Metagenomics Course

Using Raw Sequence Data to Analyze Tumor Suppressor Mutations

Investigating Cell Signaling with Gene Expression Datasets

Analysis of Microbiomes Using Free Web-Based Tools in Online and In-Person Undergraduate Science Courses

DNA Detective: Genotype to Phenotype. A Bioinformatics Workshop for Middle School to College.

Central Dogma, Dictionaries, and Functions: Using Programming Concepts to Simulate Biological Processes

Learning R for Biologists: A Mini Course Grab-Bag for Instructors

An Introduction to Eukaryotic Genome Analysis in Non-model Species for Undergraduates: A tutorial from the Genome Consortium for Active Teaching

A CURE for Salmonella: A Laboratory Course in Pathogen Microbiology and Genomics

Sequence Similarity: An inquiry based and "under the hood" approach for incorporating molecular sequence alignment in introductory undergraduate biology courses

A flexible, multi-week approach to plant biology - How will plants respond to higher levels of CO₂?

Leveraging Panel Discussions to Promote Positive Representation, Develop Science Identity, and Shift Stereotypes

Dilution and Pipetting Lesson Using Food Dyes

Enhancing the Microscopy Skills of Non-Science Majors and Nursing Microbiology Students: Promoting the Practice of Observing Multiple Fields of View Using Blood Smear Slides

An Original-Design Board Game to Increase Student Comprehension of Cellular Respiration Pathways

The Science Behind the ACTN3 Polymorphism

Facilitating Scientific Literacy Through Writing: A Write-to-Learn Assignment for Large Introductory Undergraduate Biology Courses

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