CourseSource: Resources

Teaching Tools and Strategies

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A Journal Club Project to Promote Interpreting and Presenting Information From the Primary Scientific Literature

Many undergraduate students receive little guidance on how to critically read, interpret data within, or present information from the primary scientific literature before they begin senior independent research experiences or enter professional or...

Courses: Developmental Biology Neurobiology

primary literaturejournal clubScience CommunicationfeedbackPeer reviewgroup workOral presentationProcess skillsPeer evaluationDevelopmental neurobiology

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Differential Gene Expression during Xenopus laevis Development

In Developmental Biology classes, students are challenged with understanding how differential gene expression guides embryonic development. It can be difficult for students to realize that genes need to be turned on or off at the right time and...

Courses: Developmental Biology

gene expressionXenopusearly developmentembryofertilizationin situ hybridization

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Cell Signaling Pathways - a Case Study Approach

Signaling and gene expression are fundamental to cell biology and developmental biology. Although these topics are highly interrelated, they typically appear in separate units in a course. We use a series of short problem-based learning exercises...

Courses: Cell Biology Developmental Biology

signal transductiongene expressionCell communicationgenetic disordersregulation of enzyme activity

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Using Zebrafish in a Developmental Biology Lab Course to Explore Interactions Between Development and the Environment

Important learning outcomes for biology students include the ability to develop experiments as well as pull together concepts across their coursework. The field of developmental biology, especially environmental influences on development...

Courses: Developmental Biology Science Process Skills

toxicologymorphogenesisorganogenesis

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Investigating Gene Expression and Cell Specialization in Axolotl Embryos

The process of cell specialization is critical to the formation and function of tissues in animals and plants. Although gene expression, including the regulation of transcription, is taught in most introductory cell biology courses, the...

Courses: Biochemistry and Molecular Biology Cell Biology Developmental Biology Science Process Skills

developmenttranscriptiongene expressionmodel organismembryo

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The Leaky Neuron: Understanding synaptic integration using an analogy involving leaky cups

Students have difficulty understanding synaptic integration in neural circuits, and how spatial and temporal summation combine in a target neuron to reach threshold. This Lesson uses small cups of water to represent excitatory postsynaptic...

Courses: Neurobiology

neuron physiologyspatial summationsynaptic integrationtemporal summationthreshold

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A Laboratory Module That Explores RNA Interference and Codon Optimization Through Fluorescence Microscopy Using Caenorhabditis elegans

Scientific research experiences are beneficial to students allowing them to gain laboratory and problem-solving skills, as well as foundational research skills in a team-based setting. We designed a laboratory module to provide a guided research...

Courses: Bioinformatics Cell Biology Developmental Biology Genetics Science Process Skills

microscopyC. elegansquantitative analysisinquiry-based learninggene expressionRNA interferenceCodon UsageLaboratory Module

Teaching Tools and Strategies

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The Pipeline CURE: An Iterative Approach to Introduce All Students to Research Throughout a Biology Curriculum

Participation in research provides personal and professional benefits for undergraduates. However, some students face institutional barriers that prevent their entry into research, particularly those from underrepresented groups who may stand to...

Courses: Developmental Biology Genetics Introductory Biology Science Process Skills

epigeneticsundergraduate researchmendelian inheritanceSelf-EfficacyCUREsnature of scienceResiliencecurriculum strategiesreprogramming

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Linking Genotype to Phenotype: The Effect of a Mutation in Gibberellic Acid Production on Plant Germination

Basic concepts in genetics and plant development are often taught in lecture courses without a lab component. This approach provides students with the content knowledge, but fails to make connections to research opportunities and real-world...

Courses: Cell Biology Developmental Biology Genetics Introductory Biology Plant Biology

geneticsdevelopmentmutationgerminationplantmodel organismGenotype/PhenotypeHormoneSeed

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226

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Using a Sequential Interpretation of Data in Envelopes (SIDE) approach to identify a mystery TRP channel

This lesson sought to engage students in data interpretation and to encourage critical thinking about neurophysiology in the context of temperature sensation. A family of receptors called Transient Receptor Potential (TRP) channels are activated...

Courses: Anatomy-Physiology Cell Biology Neurobiology

Cell communicationChannel specificity and activationLimitations of tools of Cell BiologyNeuronal Signaling

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A Muscular Dystrophy Case Study Illustrating the Phenotypic Effects of Mutation

Mutations in genes can lead to a variety of phenotypes, including various human diseases. Students often understand that a particular mutation in a single gene causes a disease phenotype, but it is more challenging to illustrate complex genetic...

Courses: Developmental Biology Genetics

mutationProtein Structureethicscentral dogmahuman disease

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What's in this? Students Deliberate on Endocrine Disrupting Chemicals Found in Everyday Healthcare Items to Build Democratic Skills

In helping our students become informed and active members of society, it is necessary that they develop certain skills that will empower them to improve their community and governance. These skills include communication, collaboration, and...

Courses: Anatomy-Physiology Cell Biology Developmental Biology Introductory Biology Science Process Skills

cellEndocrinehormones

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A Case Study for Teaching Toxicology: Using Whales as an Indicator for Environmental Health

One of the challenges of teaching scientific courses is helping students understand research methods, biological models, and data analysis, which can be especially difficult in classes without a laboratory component. Within the field of...

Courses: Science Process Skills Toxicology

absorptionone environmental health hypothesismetals

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A new approach to course-based research using a hermit crab-hydrozoan symbiosis

There are few feasible models for marine-focused inquiry laboratory activities, a notable shortcoming for instructors seeking to engage their students in meaningful, course-based research experiences (CUREs). We describe a multi-week CURE that...

Courses: Ecology Ecology Evolution Introductory Biology Science Process Skills

behaviorparasitismSymbiosismutualismcommensalism

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Doctor in the House: Improving Undergraduate Critical Thinking Skills Through Diagnosing Medical Case Studies

Students in undergraduate anatomy and physiology courses are not often exposed to clinical examples of homeostatic imbalances, particularly ones that provide an opportunity to diagnose a medical case. We designed a set of medical cases...

Courses: Anatomy-Physiology Science Process Skills

medicinediagnosiscardiovasculardeductive reasoningdigestiveEndocrinehomeostatic imbalancehypothetico-deductive modelurinary

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Investigating Cell Signaling with Gene Expression Datasets

Modern molecular biology is a data- and computationally-intensive field with few instructional resources for introducing undergraduate students to the requisite skills and techniques for analyzing large data sets. This Lesson helps students: (i)...

Courses: Biochemistry and Molecular Biology Cell Biology

genomicstranscriptionsignaling

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A Journal Club Project to Promote Interpreting and Presenting Information From the Primary Scientific Literature

Differential Gene Expression during Xenopus laevis Development

Cell Signaling Pathways - a Case Study Approach

Using Zebrafish in a Developmental Biology Lab Course to Explore Interactions Between Development and the Environment

Investigating Gene Expression and Cell Specialization in Axolotl Embryos

The Leaky Neuron: Understanding synaptic integration using an analogy involving leaky cups

A Laboratory Module That Explores RNA Interference and Codon Optimization Through Fluorescence Microscopy Using Caenorhabditis elegans

The Pipeline CURE: An Iterative Approach to Introduce All Students to Research Throughout a Biology Curriculum

Linking Genotype to Phenotype: The Effect of a Mutation in Gibberellic Acid Production on Plant Germination

Using a Sequential Interpretation of Data in Envelopes (SIDE) approach to identify a mystery TRP channel

A Muscular Dystrophy Case Study Illustrating the Phenotypic Effects of Mutation

What's in this? Students Deliberate on Endocrine Disrupting Chemicals Found in Everyday Healthcare Items to Build Democratic Skills

A Case Study for Teaching Toxicology: Using Whales as an Indicator for Environmental Health

A new approach to course-based research using a hermit crab-hydrozoan symbiosis

Doctor in the House: Improving Undergraduate Critical Thinking Skills Through Diagnosing Medical Case Studies

Investigating Cell Signaling with Gene Expression Datasets

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