CourseSource: Resources

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Central Dogma, Dictionaries, and Functions: Using Programming Concepts to Simulate Biological Processes

Technologies like next-generation sequencing, proteomics, and high-throughput phenotyping have transformed the way we do biology. There is a continued need for scientists with computational skills to analyze biological data while understanding the...

Courses: Bioinformatics

computationpythonJupyter notebookFunctionscentral dogmaDictionaries

Teaching Tools and Strategies

3637

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1718

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A 360˚ View of COVID-19

In March 2020, institutions underwent a massive transition to distance learning as a result of the COVID-19 pandemic. With so little time to devise new materials to maximize learning in the new virtual environment, instructors devised a variety of...

Courses: Biochemistry and Molecular Biology Bioinformatics Cell Biology Evolution Genetics Immunology Introductory Biology Microbiology Science Process Skills

geneticsImmunologyBiochemistrybioinformaticsmolecular evolutionpublic healthvirusCOVID19

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2270

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455

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A Short Laboratory Module to Help Infuse Metacognition during an Introductory Course-based Research Experience

A core competency identified in Vision and Change for undergraduate biology students is the Ability to Apply the Process of Science. Here, we describe a three-week laboratory module for students in an Introductory Cell and Molecular Biology...

Courses: Science Process Skills

metacognitiongene expressionScientific ProcessExperimenal DesignHypothesis Generationmodel organisms

Lesson

1459

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490

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Using Student Perceptions and Cooperative Learning to Unpack Primary Literature on Global Change

This case describes a three-part assignment in which students discuss key processes that regulate the stability and resilience of the Earth system and our increased risk of generating large-scale abrupt or irreversible environmental changes. Here,...

Courses: Ecology Ecology

global changeAnthropoceneEarth-systemplanetary boundary conceptthresholds

Teaching Tools and Strategies

2496

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321

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A How to Guide and Template for Designing a Puzzle Based Escape Room Game

Educational games are one active and effective way of engaging students with material while also providing additional motivation to tackle challenging concepts. A particularly popular game concept is the escape room, where students need to work in...

Courses: Biochemistry and Molecular Biology Bioinformatics Ecology Ecology Evolution Genetics Science Process Skills

Problem SolvingCollaborative WorkCorrect Misconceptions

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1221

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556

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Understanding Gastric Acid Secretion: An Active Learning Approach

The human digestive system is a diverse network of cells, tissues, and organs that is regulated by systemic (e.g., nervous and endocrine systems) and local factors (e.g., secretions, pH, and the microbiome). Given the volume of content and the...

Courses: Anatomy-Physiology

diseasesignal transductionAcid SecretionAutonomic Nervous SystemEndocrineGastric PhysiologyGPCRHistology of Gastric Pit

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2026

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357

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Interactive Video Vignettes (IVVs) to Help Students Learn Genetics Concepts

Many video resources exist to teach Mendelian genetics, but most consist of passive delivery of information rather than active construction of knowledge by users. We have created two interactive video vignettes (IVVs) that can be used together or...

Courses: Genetics Introductory Biology Science Process Skills

genotypephenotypeallelespedigreedominanceHardy-Weinberg equilibriumInheritance

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3497

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853

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Furry with a chance of evolution: Exploring genetic drift with tuco-tucos

Genetic drift is an important mechanism of evolution, yet undergraduates often fail to understand how it leads to evolutionary change due in part to its random nature. This lesson plan describes a simulation-based activity that allows students to...

Courses: Evolution

EvolutionGenetic DriftBottle neckFounder effectRandom evolutionary processes

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2130

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665

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Sequence Similarity: An inquiry based and "under the hood" approach for incorporating molecular sequence alignment in introductory undergraduate biology courses

Introductory bioinformatics exercises often walk students through the use of computational tools, but often provide little understanding of what a computational tool does "under the hood." A solid understanding of how a bioinformatics...

Courses: Biochemistry and Molecular Biology Bioinformatics Introductory Biology

BLASTmultiple sequence alignmentsequence similarityphylogramZika virusAlgorithmScoring Matrix

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1285

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352

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A first lesson in mathematical modeling for biologists: Rocs

Using a fictitious population of Rocs, a mythical species of giant raptor, students accomplish two broad objectives: 1) they undertake the process of building a first mathematical model of a population, and 2) they begin to develop their...

Courses: Ecology Ecology Introductory Biology Science Process Skills

population ecologypopulation modelingdiscrete generationpopulation management

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4467

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448

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Teaching Advanced Concepts in Regulation of the Lac Operon With Modeling and Simulation

Success in biochemistry and other life science courses requires that students understand important biological concepts. One of these concepts is how gene regulation ensures that homeostasis is maintained in an organism. The lac operon is a...

Courses: Biochemistry and Molecular Biology

gene regulationinducible operonProkaryotic cellPhosphoenolpyruvate transferase system (PTS)

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282

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The Leaky Neuron: Understanding synaptic integration using an analogy involving leaky cups

Students have difficulty understanding synaptic integration in neural circuits, and how spatial and temporal summation combine in a target neuron to reach threshold. This Lesson uses small cups of water to represent excitatory postsynaptic...

Courses: Neurobiology

neuron physiologyspatial summationsynaptic integrationtemporal summationthreshold

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617

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Predicting and classifying effects of insertion and deletion mutations on protein coding regions

Mutations in genes can affect the encoded proteins in multiple ways, and some of these effects are counterintuitive. As for any other knowledge, students must create their own deep understanding of the Central Dogma. Students may not develop this...

Courses: Bioinformatics Genetics Science Process Skills

mutationcentral dogmatranslationframeshift

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603

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Student-Driven Design-and-Improve Modules to Explore the Effect of Plant Bioactive Compounds in Three Model Organisms

Engaging and supporting introductory level students in authentic research experiences during required coursework is challenging. Plant bioactive compounds attract students' natural curiosity as they are found in many familiar items such as...

Courses: Introductory Biology Science Process Skills

statisticsLabCUREInquiryresearch skillscaterpillardaphniadrugsscience process

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Central Dogma, Dictionaries, and Functions: Using Programming Concepts to Simulate Biological Processes

A 360˚ View of COVID-19

A Short Laboratory Module to Help Infuse Metacognition during an Introductory Course-based Research Experience

Using Student Perceptions and Cooperative Learning to Unpack Primary Literature on Global Change

A How to Guide and Template for Designing a Puzzle Based Escape Room Game

Understanding Gastric Acid Secretion: An Active Learning Approach

Interactive Video Vignettes (IVVs) to Help Students Learn Genetics Concepts

Furry with a chance of evolution: Exploring genetic drift with tuco-tucos

Sequence Similarity: An inquiry based and "under the hood" approach for incorporating molecular sequence alignment in introductory undergraduate biology courses

A first lesson in mathematical modeling for biologists: Rocs

Teaching Advanced Concepts in Regulation of the Lac Operon With Modeling and Simulation

The Leaky Neuron: Understanding synaptic integration using an analogy involving leaky cups

Predicting and classifying effects of insertion and deletion mutations on protein coding regions

Student-Driven Design-and-Improve Modules to Explore the Effect of Plant Bioactive Compounds in Three Model Organisms

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