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Single Cell Insights Into Cancer Transcriptomes: A Five-Part Single-Cell RNAseq Case Study Lesson
There is a growing need for integration of “Big Data” into undergraduate biology curricula. Transcriptomics is one venue to examine biology from an informatics perspective. RNA sequencing has largely replaced the use of microarrays for...
bioinformatics cancer transcriptomics high-throughput Data wrangling Single cell RNA sequencingq
Lesson
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27

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Follow the Sulfur: Using Yeast Mutants to Study a Metabolic Pathway
Students are frequently overwhelmed by the complexity of metabolic pathways and they think they have "learned" the pathway when they have memorized the individual reactions.  This laboratory lesson helps students to understand the...
Selection yeast Metabolism cysteine media methionine mutant Pathway sulfur
Lesson
68

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31

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Investigating Enzyme Structure and Function Through Model-Building and Peer Teaching in an Introductory Biology Course
A foundational knowledge of the relationship between structure and function is critical to understanding how enzymes work. The seemingly invisible nature of these molecular interactions makes it challenging for undergraduate students to...
structure-function Enzyme allosteric regulation competitive inhibition feedback inhibition noncompetitive inhibition product substrate
Lesson
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8

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Using Comics to Make Science Come Alive
Students often see science as a fragmented set of facts to be memorized, rather than concepts and processes that are relevant in their everyday lives. This is especially true for non-science majors, who represent the vast majority of all college...
role of science in society
Teaching Tools and Strategies
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Drawing flowcharts of lab protocols helps students prepare for biology labs
With the publishing of the Vision and Change report, we know it is best practice to include authentic research experiences in our undergraduate science lab classes. One big challenge in teaching so-called "wet lab" classes is figuring...
laboratory molecular biology Undergraduate protocol flowchart
Lesson
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9

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Fly Exercise: A Simple Experiment to Test the Physiological Effects of Exercise on a Model Organism
Model organisms are commonly used to study and experimentally explore biological processes in ways that are technically or ethically not possible in humans. For this reason, model organisms are an essential component of scientific research and...
exercise enzyme kinetics metabolite concentration model species physical activity
Lesson
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Student-Driven Design-and-Improve Modules to Explore the Effect of Plant Bioactive Compounds in Three Model Organisms
Engaging and supporting introductory level students in authentic research experiences during required coursework is challenging. Plant bioactive compounds attract students' natural curiosity as they are found in many familiar items such as...
statistics Lab CURE Inquiry research skills caterpillar daphnia drugs science process
Teaching Tools and Strategies
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6

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Preparing Student Study Guides through Peer Collaboration in the Technological Era
Incorporating active learning exercises into large lecture courses is particularly challenging, especially when it comes to examination preparation materials. Traditionally, study guides are used as a tool to guide student learning and review...
active learning Discussion Study Skills
Essay
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Squirreling from Afar: Adapting Squirrel-Net Modules for Remote Teaching and Learning
The shift from face-to-face instruction to remote teaching and learning has proven to be a challenging endeavor for many reasons, including lack of time, resources, and inspiration. Lab courses, the "hands-on" portion of many curricula,...
online learning behavioral ecology CUREs Remote teaching field ecology Squirrel Squirrel-Net
Lesson
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How Many Squirrels Are in the Shrubs? A Lesson Plan for Comparing Methods for Population Estimation
Estimating the population sizes of animals is a key skill for any student interested in ecology, conservation, or management. However, counting animals in natural habitats is difficult, and the many techniques that exist each rely on assumptions...
population ecology wildlife management population estimation sciuridae Squirrel-Net
Lesson
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Squirreling Around for Science: Observing Sciurid Rodents to Investigate Animal Behavior
Hands-on research experiences are important opportunities for students to learn about the nature of inquiry and gain confidence in solving problems. Here, we present an inquiry-based lesson plan that investigates the foraging behavior of sciurid...
foraging behavior behavioral ecology Sciurid Squirrel Squirrel-Net Trade-off Vigilance
Teaching Tools and Strategies
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Adaptation and Facilitation of Small Group Activities in an Online Introductory Biology Class
In spring 2020, the sudden mid-semester closure of my campus in response to the global COVID-19 pandemic necessitated a rapid transition to emergency online learning. Consequently, I adapted the small group activities and facilitation methods of...
Cellular communication Neuronal function Neuronal structure
Lesson
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38

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Biodiversity Show and Tell: An Accessible Activity to Encourage Students to Explore the Tree of Life
An appreciation of organismal diversity is a requirement for understanding evolution and ecology, and can serve as a source of amazement and wonder that inspires students to enjoy biology. However, biodiversity can be a challenging subject to...
Evolution ecology Biodiversity
Lesson
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A Remote Introductory Biology Lab Using Backyard Birdwatching to Teach Data Analysis and Communication
Asking questions, designing experiments, collecting data and interpreting those data, and communicating the results are some of the most important concepts an undergraduate biology lab can teach students. When the SARS-CoV2 pandemic forced our...
ecology data analysis data collection
Lesson
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A Lesson on Matter and Energy at the Organismal Scale: Linking Patterns and Processes Across Diverse Taxa
Pathways and transformations of energy and matter (PTEM) are a conceptually challenging but essential component of biological literacy. Curricular gaps about PTEM nevertheless remain; although lessons targeting PTEM at small scales (chemical,...
plants energy Animals fungi matter organismal scale