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    Role of Crop Genetic Diversity on Pathogen Impact: The Tale of Two Pathogens
    Introductory genetics courses are part of the core curriculum in many different fields, including plant breeding, animal science, biology, microbiology, and natural resource management. Concepts involving genes, inheritance, evolution, and genome...
    plant pathology genetic diversity Disease Triangle Modes of Reproduction
    Lesson
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    Splicing it Together: Using Primary Data to Explore RNA Splicing and Gene Expression in Large-Lecture Introductory Biology
    At the heart of scientific ways of knowing is the systematic collection and analysis of data, which is then used to propose an explanation of how the world works. In this two-day module, students in a large-lecture course are immersed in a...
    gene regulation transcription gene expression central dogma repressor alternative splicing mRNA processing Activator Transcription factors
    Lesson
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    Electron Location, Location, Location: Understanding Biological Interactions
    Introductory Biology courses typically introduce the structure and function of biomolecules such as proteins and nucleic acids. To understand biomolecules fully, students require knowledge of fundamental chemistry concepts such as covalent...
    hydrogen bonds hydrophobicity/hydrophilicity polar and non-polar covalent bonds
    Lesson
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    Meiosis Remodeled: Inclusion of New Parts to Poppit Bead Models Enhances Understanding of Meiosis
    A long-standing tradition uses strings of poppit beads of different colors to model meiosis, especially to show how segments of paired homologous chromosomes are recombined. Our use of orthodontic latex bands to model cohesion of sister...
    meiosis chiasma formation chromosome recombination
    Teaching Tools and Strategies
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    A 360˚ View of COVID-19
    In March 2020, institutions underwent a massive transition to distance learning as a result of the COVID-19 pandemic. With so little time to devise new materials to maximize learning in the new virtual environment, instructors devised a variety of...
    genetics Immunology Biochemistry bioinformatics molecular evolution public health virus COVID19
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    204

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    How Do Kidneys Make Urine From Blood? Qualitative and Quantitative Approaches to Filtration, Secretion, Reabsorption, and Excretion
    The function of the kidneys is to help maintain a constant internal environment (homeostasis) by regulating the volume and chemical composition of the blood. This regulation occurs via three fundamental processes: filtration, secretion, and...
    collecting duct excretion glomerular filtration rate (GFR) nephron tubule reabsorption renal corpuscle section
    Lesson
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    Targeting Misconceptions in the Central Dogma by Examining Viral Infection
    Understanding the central dogma and how changes in gene expression can impact cell function requires integration of several topics in molecular biology. Students often do not make the necessary connections between DNA structure, transcription,...
    data transcription virus translation protein function membrane transport Predictions
    Teaching Tools and Strategies
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    A Remote-Learning Framework for Student Research Projects: Using Datasets to Teach Experimental Design, Data Analysis and Science Communication
    Remote learning often requires an alternative to hands-on, student-designed research projects. To this end, we created a package of scaffolded assignments to support introductory students through the research process using datasets from past...
    population growth physiology ecotoxicology photosynthesis
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    Single Cell Insights Into Cancer Transcriptomes: A Five-Part Single-Cell RNAseq Case Study Lesson
    There is a growing need for integration of “Big Data” into undergraduate biology curricula. Transcriptomics is one venue to examine biology from an informatics perspective. RNA sequencing has largely replaced the use of microarrays for whole...
    bioinformatics cancer transcriptomics high-throughput Data wrangling Single cell RNA sequencingq
    Lesson
    624

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    327

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    Follow the Sulfur: Using Yeast Mutants to Study a Metabolic Pathway
    Students are frequently overwhelmed by the complexity of metabolic pathways and they think they have "learned" the pathway when they have memorized the individual reactions.  This laboratory lesson helps students to understand the...
    Selection yeast Metabolism cysteine media methionine mutant Pathway sulfur
    Lesson
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    Investigating Enzyme Structure and Function Through Model-Building and Peer Teaching in an Introductory Biology Course
    A foundational knowledge of the relationship between structure and function is critical to understanding how enzymes work. The seemingly invisible nature of these molecular interactions makes it challenging for undergraduate students to...
    structure-function Enzyme allosteric regulation competitive inhibition feedback inhibition noncompetitive inhibition product substrate
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    Using Comics to Make Science Come Alive
    Students often see science as a fragmented set of facts to be memorized, rather than concepts and processes that are relevant in their everyday lives. This is especially true for non-science majors, who represent the vast majority of all college...
    role of science in society
    Teaching Tools and Strategies
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    Drawing flowcharts of lab protocols helps students prepare for biology labs
    With the publishing of the Vision and Change report, we know it is best practice to include authentic research experiences in our undergraduate science lab classes. One big challenge in teaching so-called "wet lab" classes is figuring...
    laboratory molecular biology Undergraduate protocol flowchart
    Lesson
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    Fly Exercise: A Simple Experiment to Test the Physiological Effects of Exercise on a Model Organism
    Model organisms are commonly used to study and experimentally explore biological processes in ways that are technically or ethically not possible in humans. For this reason, model organisms are an essential component of scientific research and...
    exercise enzyme kinetics metabolite concentration model species physical activity
    Lesson
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    Student-Driven Design-and-Improve Modules to Explore the Effect of Plant Bioactive Compounds in Three Model Organisms
    Engaging and supporting introductory level students in authentic research experiences during required coursework is challenging. Plant bioactive compounds attract students' natural curiosity as they are found in many familiar items such as...
    statistics Lab CURE Inquiry research skills caterpillar daphnia drugs science process