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    Bloom's Cognitive Level
    Vision and Change Core Competencies
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    Lesson
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    Using Synthetic Biology and pClone Red for Authentic Research on Promoter Function: Introductory Biology (identifying new promoters)
    Students often memorize the definition of a transcriptional promoter but fail to fully understand the critical role promoters play in gene expression. This laboratory lesson allows students to conduct original research by identifying and...
    bacteria synthetic biology gene regulation transcription student research central dogma cloning promoter reporter gene/protein
    Lesson
    566

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    200

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    Authentic Ecological Inquiries Using BearCam Archives
    Learning through authentic scientific inquiries is essential for understanding the nature and process of science and for developing critical thinking and communication skills. It is logistically challenging, however, to offer experiences of...
    behavior interspecific interactions Peer review authentic inquiry intra-specific interactions
    Lesson
    417

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    138

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    Air Quality Data Mining: Mining the US EPA AirData website for student-led evaluation of air quality issues
    Air pollution directly affects human health endpoints including growth, respiratory processes, cardiovascular health, fertility, pregnancy outcomes, and cancer. Therefore, the distribution of air pollution is a topic that is relevant to all, and...
    data mining environmental justice air quality airpollution spatial reasoning
    Teaching Tools and Strategies
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    218

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    A Strategy for Teaching Undergraduates to Write Effective Scientific Results Sections
    Most undergraduate instructors would agree that learning to write about data in the style of a scientific research paper is a worthy goal for their students.  However, many hesitate to tackle the challenge of teaching scientific writing in...
    data analysis primary literature scientific writing communicating science
    Essay
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    49

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    An Active Textbook Converts "Vision and Tweak" to Vision and Change
    Multiple reports over more than a century have documented the problems with the way introductory biology has been taught in most colleges and universities. An influential recent report, Vision and Change in Undergraduate Biology Education, has...
    Vision and Change active learning introductory biology Flipped classroom Undergraduate core competencies core concepts active textbook curriculum reform
    Teaching Tools and Strategies
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    71

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    An Open Source, Collaborative Electronic Notebook for Undergraduate Laboratory Classes
    To overcome many of the limitations of the paper laboratory notebook (PLN), we developed an electronic laboratory notebook (e-LN) for the Dynamic Genome course at the University of California. The Dynamic Genome course is an authentic research...
    data collection Data annotation Notebook Skills
    Lesson
    554

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    207

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    Building a Model of Tumorigenesis: A small group activity for a cancer biology/cell biology course
    The multistep nature of tumorigenesis is a foundational concept in the context of Cancer Biology. Many students do not appreciate the complex nature of cancer development nor do they understand how scientists are able to unravel the molecular...
    pathways cancer Molecular Alterations Retrospective data Tumorigenesis
    Lesson
    811

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    228

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    Exploration of the Human Genome by Investigation of Personalized SNPs
    Students often shy away from tedious bioinformatics approaches to exploring their genomes. However, in our expanding digital world these skills are some of the most relevant and valuable. To increase students' interest in their own genomes, I...
    UCSC genome browser single nucleotide polymorphism Genome wide association studies Genomic organization
    Lesson
    370

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    79

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    Infectious Chocolate Joy with a Side of Poissonian Statistics: An activity connecting life science students with subtle physics concepts
    Introductory physics courses are required for many programs in the life sciences, yet traditional curricula fail to help students meaningfully connect physical concepts with biological systems.  In this lesson, we describe an activity taught...
    quantitative biology HIV multiplicity of infection Poisson Distribution Physics for biologists
    Lesson
    1708

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    518

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    Lights, Camera, Acting Transport! Using role-play to teach membrane transport
    Lights, Camera, Acting Transport! is an active and unique role-play exercise designed to teach introductory biology students basic concepts of passive and active membrane transport. The activity involves three acts in which students, representing...
    ATP carriers channels co-transport electrogenic pump facilitated diffusion membrane transport passive transport primary active transport simple diffusion
    Lesson
    328

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    206

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    Using Undergraduate Molecular Biology Labs to Discover Targets of miRNAs in Humans
    Incorporating authentic research experiences into undergraduate labs, while shown to be particularly effective at engaging and retaining students in STEM majors, can be difficult to accomplish within the constraints of resource availability or...
    gene regulation microRNAs gene expression
    Lesson
    506

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    208

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    Why do Some People Inherit a Predisposition to Cancer? A small group activity on cancer genetics
    Before undergraduate students take a genetics course they generally know cancer has a genetic basis and involves the proliferation of cells; however, many are uncertain about why only a subset of people have a predisposition to cancer and how that...
    cancer Inheritance patterns Probability calculation Proto-oncogene Tumor Suppressor Gene
    Lesson
    935

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    169

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    You and Your Oral Microflora: Introducing non-biology majors to their “forgotten organ”
    With limited time available for laboratory activities, introductory science courses for non-science majors typically use the laboratory period to reinforce material that was previously presented during lecture. This practice was true of a human...
    bacteria microbiome BLAST microbes DNA replication Polymerase chain reaction (PCR)
    Lesson
    498

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    236

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    Sex-specific differences in Meiosis: Real-world applications
    In traditional classrooms, students are typically presented with facts that they are asked to memorize and recall during an exam.  The rapid explosion of available scientific facts in recent years has made this model of teaching...
    meiosis Reproduction Aneuploidy Gamete Non-disjunction Oocyte Sperm Trisomy
    Lesson
    422

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    179

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    Modeling the Research Process: Authentic human physiology research in a large non-majors course
    Laboratory experiences in large-enrollment introductory science courses often utilize “cookie-cutter style” laboratory experiences due to the relative simplicity of setting up the lab stations, as well as a need to teach students...
    data analysis hypothesis testing experimental design physiology