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    Lesson
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    Online Information Literacy: Applying the CRAAP Test to Vaccine (Mis)information
    Teaching scientific literacy skills can help combat the propagation of misinformation online. This lesson is intended to give students practice identifying reliable scientific information on the Internet, in the context of vaccine safety. It was...
    Vaccines immunity reliability
    Lesson
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    16

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    Garden Variety Mutations: Using Primary Data to Understand the Central Dogma in Large-Lecture Introductory Biology
    The ability to interpret and create an argument from data is a crucial skill for budding scientists, yet one that is seldom practiced in introductory courses. During this argumentation module, students in a large lecture class will work in groups...
    mutation transcription gene expression central dogma translation gel electrophoresis Genotype/Phenotype
    Lesson
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    44

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    Responsible and Ethical Conduct of Research: Instruction on Plagiarism
    Helping students understand where they should provide citations in research manuscripts is an essential aspect of training them in the responsible and ethical conduct of research. This Lesson comprises about 35 minutes of in-class work to help...
    writing ethics plagiarism paraphrase quote
    Lesson
    1201

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    144

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    Splicing it Together: Using Primary Data to Explore RNA Splicing and Gene Expression in Large-Lecture Introductory Biology
    At the heart of scientific ways of knowing is the systematic collection and analysis of data, which is then used to propose an explanation of how the world works. In this two-day module, students in a large-lecture course are immersed in a...
    gene regulation transcription gene expression central dogma repressor alternative splicing mRNA processing Activator Transcription factors
    Lesson
    2860

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    175

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    Does Organelle Shape Matter?: Exploring Patterns in Cell Shape and Structure with High-Throughput (HT) Imaging
    Organelle structure has been studied and visualized for decades; however, publicly available databases that use improved high-throughput microscopy of gene-edited cell lines have recently revolutionized the amount and quality of information now...
    modeling case study microscopy structure Organelles High-throughput (HT) Endoplasmic Reticulum (ER) Fluorescent microscopy Human Cell Biology
    Lesson
    1371

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    254

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    Moths and Frogs and E. coli, Oh My!: Agent-based Modeling of Evolutionary Systems
    In evolution classrooms, introducing and reinforcing the idea of genetic drift and random selection can be challenging, as can be reinforcing appropriate mental models of evolution. Agent-based models offer students the opportunity to conduct a...
    modeling Evolution ecology agent-based modeling Genetic Drift environmental science Natural Selection competitive coevolution simulation modeling evolutionary reasoning
    Lesson
    2203

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    355

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    Investigating Enzyme Structure and Function Through Model-Building and Peer Teaching in an Introductory Biology Course
    A foundational knowledge of the relationship between structure and function is critical to understanding how enzymes work. The seemingly invisible nature of these molecular interactions makes it challenging for undergraduate students to...
    structure-function Enzyme allosteric regulation competitive inhibition feedback inhibition noncompetitive inhibition product substrate
    Lesson
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    490

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    Student-Driven Design-and-Improve Modules to Explore the Effect of Plant Bioactive Compounds in Three Model Organisms
    Engaging and supporting introductory level students in authentic research experiences during required coursework is challenging. Plant bioactive compounds attract students' natural curiosity as they are found in many familiar items such as...
    statistics Lab CURE Inquiry research skills caterpillar daphnia drugs science process
    Lesson
    840

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    199

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    Cutthroat trout in Colorado: A case study connecting evolution and conservation
    Evaluation of evidence is a key process skill for the core competencies of applying the process of science and using quantitative reasoning. This case study enables upper-division biology students to practice these skills by applying evolutionary...
    population genetics phylogenetics Speciation divergence gene flow
    Lesson
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    626

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    Mapping a Mutation to its Gene: The "Fly Lab" as a Modern Research Experience
    Although genetics is an invaluable part of the undergraduate biology curriculum, it can be intimidating to students as well as instructors: Students must reduce their reliance on memorization and dive deep into quantitative analysis, and...
    genetics bioinformatics drosophila chi-square analysis complementation mapping mode of inheritance three-point mapping
    Lesson
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    768

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    A CRISPR/Cas Guide RNA Design In Silico Activity
    CRISPR biotechnologies inspired by the Clustered Regularly Interspaced Short Palindromic Repeat RNA-guided nuclease adaptive bacterial immune system have revolutionized biology research and become ubiquitous tools for hypothesis and...
    bioinformatics gene expression genetic basis of disease CRISPR/Cas9 genetic engineering in silico
    Essay
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    152

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    Online Adaptation of the Cell Engineer/Detective Lesson
    One of the most fundamental themes of biology is the relationship between structure and function, which is particularly evident when it comes to cells; however, the traditional cartoon depictions of cells that are often used to help teach the...
    cell function Cell Structure Organelles
    Lesson
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    155

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    Interactive Video Vignettes (IVVs) to Help Students Learn Genetics Concepts
    Many video resources exist to teach Mendelian genetics, but most consist of passive delivery of information rather than active construction of knowledge by users. We have created two interactive video vignettes (IVVs) that can be used together or...
    genotype phenotype alleles pedigree dominance Hardy-Weinberg equilibrium Inheritance
    Lesson
    357

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    92

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    From Cre/LoxP to Fate Maps: Inclusive and Equitable Approaches for Engaging Developmental Biology Students in Experimental Design
    Engaging first generation underrepresented minority students in the process of inquiry in developmental biology is important to increase diversity in future graduate STEM education. One important challenge is how we design curricula to foster...
    experimental design C. elegans Cre/LoxP Fate map heart development heart regeneration mouse reporter construct zebrafish
    Lesson
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    Assessing Urban Biodiversity With the eBird Citizen Science Project: A Course-Based Undergraduate Research Experience (CURE) Module
    The eBird citizen science module takes advantage of technology tools and online resources developed by the Cornell Laboratory of Ornithology (http://ebird.org) to achieve several learning objectives embedded in a semester-long upper-level biology...
    data citizen science community Biodiversity Species hypothesis habitat