Resources
81 total view(s), 63 download(s)
- Deme_20.xls(XLS | 414 KB)
- Deme_10.xls(XLS | 80 KB)
- License terms
Overview
This workbook simulates the population genetics of a single gene with two alleles. It can simultaneously model up to three local populations, which may differ in their selection coefficients.
Popular Text Citations
Snustad D P, Simmons M J (2003) Principles of Genetics. 3rd Edition. New York : John Wiley & Sons, Inc.
Crow J F (1986) Basic Concepts in Population, Quantitative, and Evolutionary Genetics. New York : W. H. Freeman and Company.
Li C C (1955) Population Genetics. Chicago : University of Chicago Press.
Freeman S. and Herron J. C. 2004. Evolutionary Analysis, 2nd edition. Pearson Prentice Hall: Upper Saddle River, New Jersey.
Research Articles
Marmor M., Sheppard H.W., Donnell D., et al. 2001. Homozygous and heterozygous CCR5-(delta)32 genotypes are associated with resistance to HIV infection. J. Acquir. Immune Defic. Syndr. 27: 472-481.
Kokkotou E., Philippon V., Gueye-Ndiaye A., et al. 1998. Role of the CCR5 delta 32 allele in resistance to infection in west Africa. J. Hum. Virol. 1: 469-474.
Wellek S, 2004 Tests for establishing compatibility of an observed genotype distribution with Hardy-Weinberg Equilibrium in the case of a biallelic locus. Biometrics 60: 694-703.
Wittke-Thompson JK, Pluzhnikov A, Cox NJ, 2005 Rational inferences about departures from Hardy-Weinberg equilibrium. American Journal of Genetics 76: 967-86.
Hosking L, Lumsden S, Lewis K, Yeo A, McCarthy L, Bansal A, Riley J, Purvis I, Xu CF, 2004 Detection of genotyping errors by Hardy-Weinberg equilibrium testing. European Journal of Human Genetics 12: 395-9.
Education Research & Pedagogical Materials
Kaplan R. 1997. PopBio.
Alstad D.N. 2024. Populus.
Genes, Environment, and Human Behavior. Biological Sciences Curriculum Study (BSCS), 152pp (Snapshot: 2005-04-25)
Louisiana State University. 2006. Software for Population Genetic Analyses. (Snapshot: 2006-04-26)
Price F. and Vaughan V. 1998. EVOLVE. In The BioQUEST Library, Vol. VI (Jungck J.R., Calley J.N., Donovan S., Everse S.J., Soderberg P., Stanley E., Stewart J., eds). Academic Press: San Diego, CA.
Soderberg P. and Price F. 2003. An examination of problem-based teaching and learning in population genetics and evolution using EVOLVE, a computer simulation. Int. J. Sci. Educ. 25: 35-55.
Tutorial & Background Materials
The Hardy-Weinberg Equilibrium by John W. Kimball (Snapshot: 2007-01-26)
Citation
Researchers should cite this work as follows:
- Weisstein, T. E. (2024). Deme 2.0. ESTEEM, QUBES Educational Resources. doi:10.25334/QRCF-8649
Fundamental Mathematical Concepts
Developed By
Primary Reference
Weinberg, W., 1908 Ãœber den Nachweis der Vererbung beim Menschen. Jahresh. Wuertt. Ver. vaterl. Natkd. 64:369-382.
Hardy, G. H., 1908 Mendelian proportions in a mixed population. Science 28:49-50.