Regulation

Similar principles govern the operation and regulation of biological processes across cellular, physiological, and ecological scales.  Resources connected to this theme include:

The Serengeti Rules: the book by Sean B. Carroll and the film by Passion Pictures and HHMI Tangled Bank Studios

HHMI BioInteractive Resources:

Keystone Species and Trophic Cascades

Population Dynamics Click and Learn

Serengeti Wildebeest Population Regulation

Temperature Regulation in Dinosaurs

Sex Determination and Sex Verification Hormone Testing in Athletes

Fat Cell Regulation by the PPAR-gamma Receptor

Evolving Switches, Evolving Bodies in Stickleback Fish

p53 Gene Regulation and Cancer

Regulation of the Lactase Gene

Educator Publications:

In 2018, educators explored regulation as a unifying theme in biology and produced resources that support HHMI BioInteractive themes on regulation

In this activity students use the HHMI Population Growth Models interactive to explore R0 for diseases and discuss the importance of connecting population ecology to current events like the COVID-19 global pandemic.
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214
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09.2020

Teaching Population Dynamics with Data and HHMI BioInteractive

Abby Kula, Kristine Grayson

Version: 1.0

Presented at NABT 2019, we demonstrate how the Population Dynamics Click & Learn resource can be customized for any organism - using the Lionfish invasion as an example
population growth, HHMI BioInteractive, introductory, Presentation, Online course, Teaching material, Lecture, High School, Reference material, Undergraduate, Homework, 1 Hour, Workshop material
1.1K
478
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11.2019

Modeling Trophic Interactions in Rice Agriculture: A Jigsaw Approach

Fernando Nieto, Kiersten Nicole Newtoff, Kristine Grayson, Emily Nodine, Brian Robert Shmaefsky

Version: 1.0 Adapted From: Understanding Trophic Interactions in Rice Agriculture: A Jigsaw Approach v1.0

Students explore four different issues related to trophic interactions that affect modern rice agriculture practices and consider relationships between these issues using Lotka and Volterra predator/prey model.
mathematical model, Lotka-Volterra, jigsaw, food chain, trophic cascades, predator-prey interactions, food web, introductory, Online course, Teaching material, Lecture, High School, Undergraduate, Homework, Advanced, Majors, Non-majors, More than 1 hour
348
202
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01.2019

Regulation of Sex Determination

Jessica Ashley Allen, Christie Landry, Laura Pickell, Deborah Taylor

Version: 1.0

This activity accompanies the HHMI BioInteractive module Sex Verification of Athletes (​https://www.hhmi.org/biointeractive/testing-athletes​). It provides students with exercises to explore the aspects of human anatomy and physiology.
introductory, Teaching material, Undergraduate, Majors, Non-majors, Less than 1 hour
615
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01.2019

Regulation of Gene Expression and Adipogenesis by PPAR-γ

Gary Laverty, Thomas John Peters, Juan Sebastián Ramírez-Lugo, Denise Levin Signorelli, Saumya Ramanathan

Version: 1.0

Students learn about transcriptional regulation of PPAR-γ, an important controller of adipose tissue stores and energy metabolism through a drawing/coloring activity of the different components involved in controlling PPAR-γ activation.
gene expression, small group work, transcriptional regulation, adipose tissue, fat metabolism, repressor, introductory, Online course, Teaching material, Lecture, Undergraduate, Majors, Non-majors, Less than 1 hour
701
390
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01.2019

Understanding Trophic Interactions in Rice Agriculture: A Jigsaw Approach

Kiersten Nicole Newtoff, Fernando Nieto, Emily Nodine, Brian Robert Shmaefsky, Kristine Grayson

Version: 1.0

Students explore four different issues related to trophic interactions that affect modern rice agriculture practices and consider relationships between these issues.
jigsaw, food chain, trophic cascades, food web, introductory, Online course, Teaching material, Lecture, High School, Undergraduate, Homework, Majors, Non-majors, More than 1 hour
479
818
1
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01.2019