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Potential Scenario
142
views
47
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0
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2008-Huangi-Lu-Modeling long-term longitudinal HIV dynamics with applications to an AIDS clinical studyÂ
To better understand the factors responsible for the virological failure, this paper develops the mechanism-based nonlinear differential equation models for characterizing long-term viral dynamics with ARV therapy.
longitudinal data
AIDS
antiretroviral drug therapy
Bayesian nonlinear mixed-effects
time-varying drug efficacy
HIV dynamics
Potential Scenario
173
views
69
downloads
0
comments
2002-Nelson-Perelson-Mathematical analysis of delay differential equations models of HIV-1 infection
We develop and analyze a set of models that include intracellular delays, combination antiretroviral therapy, and the dynamics of both infected and uninfected T cells.
infection
HIV
T cells
Potential Scenario
136
views
80
downloads
0
comments
2014-Wang-EtAl-Estimating Mixed-Effects Differential Equation Models
When multiple replicates of measurements are available for the dynamic process, it is of great interest to estimate mixed-effects in the ODE model for the process. We propose a semiparametric method to estimate mixed-effects ODE models.
pharmacokinetics
dynamic models
smoothing
spline
mixed-effects models
HiV combination therapy
Potential Scenario
149
views
103
downloads
0
comments
2017-Fred_Adler-Mathematically Modeling Asthma
Our Asthma models have examined how a viral infection can tip the immune system into a different state, with the potential to predispose an individual to future asthma
infection
asthma
immune response
rhinovirus
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