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    Potential Scenario
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    2017-Helen-Byrne-Further Mathematics Biology
    These studies will be in the context of ecological, biological and biochemical applications.
    epidemicschemotaxisenzyme-substrateion channelsnerve pulsesgene proagationtumour
    Free Online Textbook
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    2012-Brian_Ingalls-Mathematical Modelling in Systems Biology An Introduction
    This is a comprehensive text with much biology background to motivate the mathematical modeling, exercises and answers, and many rich examples.
    spatialsensitivity analysisgene regulatory networksstochasticbifurcationmetabolic networkselectrophysiologytransductionrate lawsbiochemical reactions
    Potential Scenario
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    2008-Brewer-EtAl-Fitting ordinary differential equations to short time course data
    In this paper, we present a survey of existing algorithms and describe the main approaches. We also introduce and evaluate a new efficient technique for estimating ODEs linear in parameters particularly suited to situations where noise levels are...
    time seriesEvaluation SPLINEgeneleast squaresbifurcation
    Potential Scenario
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    2006-Wilensky-Reisman-Thinking Like a Wolf a Sheep or a Firefly
    We describe a computation-based approach that enables students to investigate the connections between different biological levels using agent-based, embodied modeling tools.
    simulationNetLogopredator-preyagent-basedwolffox
    Potential Scenario
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    2013-Alicia_Caldwell-Students Rise to the Challenge of Modeling Yeast Growth Despite Sour Hiccups from Imperfect Data
    This paper describes a lab in which students in an Applied Mathematics in Biology course observe the growth of Saccharomyces cerevisiae, a yeast strain, in differing sugar concentrations for use in learning modeling.
    Saccharomyces cerevisiaelogisticyeastdeathgrowthsugaralcohol
    Modeling Scenario
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    1-098-NeuronDetection-ModelingScenario
    Students study a linear, first order, one-dimensional ordinary differential equation (ODE) and learn how it can help understand basics of neural dynamics. The modeling framework is known in mathematical neuroscience as ``integrate-and-fire''...
    biologyneuroscienceneuron physiologyvoltageintegrate and firethrefholscoincidence detectionRC circuit
    Potential Scenario
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    2012-Transtrum-Qiu-Optimal experiment selection for parameter estimation in biological differential equation models
    We explore the question to what extent parameters can be efficiently estimated by appropriate experimental selection.
    experimental designsystems biologyAssociation & Data Fittingreaction ratesdecay rates
    Potential Scenario
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    2011-GA_Koch-Noble-Drugs in the Classroom Using Pharmacokinetics to Introduce Biomathematical Modeling
    By beginning with simple model involving the half-life of a drug, students take advantage of their mathematical abilities to explore the biology.
    Biomathematicspharmacokinetics
    Potential Scenario
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    2018-Robert_Phair-Differential_equation_methods_for_simulation_of_GFP_kinetics_in_non–steady_state_experiments
    Here, we derive new tracer kinetic analytical methods for non–steady state biological systems by constructing mechanistic nonlinear differential equation models of the underlying cell biological processes.
    protein quality controlkineticsCellssteady statechemical kineticsfluouresencephotoactivationinytracellular
    Potential Scenario
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    2018-Dyjuan_Tatro-The_Mathematics_of_Cancer-Fitting_Gompertz_Equation_to_Tumor_Growth
    Fitting the Gompertz Model to long term breast cancer study data, this project ascertains gompertzian parameters that can be used to predicts tumor growth as a function of time.
    tumorgrowthGompertzfittingparameter
    Potential Scenario
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    2017-D_Goulet-Modeling, Simulating, and Parameter Fitting of Biochemical Kinetic Experiments
    In many chemical and biological applications, systems of differential equations containing unknown parameters are used to explain empirical observations and experimental data. The differential equations are typically nonlinear.
    optimizationBiochemistrysensitivity analysischromatographymass actioncluster analysisconservation lawsdimerizationestrogen receptor protein
    Potential Scenario
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    2002-Nelson-Perelson-Mathematical analysis of delay differential equations models of HIV-1 infection
    We develop and analyze a set of models that include intracellular delays, combination antiretroviral therapy, and the dynamics of both infected and uninfected T cells.
    infectionHIVT cells
    Modeling Scenario
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    6-019-EnablingEpidemicExploration-ModelingScenario
    We became aware of several interesting possibilities for a modeling opportunity with data and we invited you to explore the several routes to parameter estimation in a SIR model with respect to the data offered.
    Akaike Information CriterionMichaelis-Mentenepidemicsaturationgradientleast sum of square errors
    Potential Scenario
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    2017-Justin_Krueger-Parameter Estimation Methods for Ordinary Differential Equation Models with Applications to Microbiology
    We demonstrate the feasibility of principal differential analysis using simulation studies and then apply the method to intestinal and vaginal microbiota data.
    microbiologyLotka Volterrramicrobiota
    Potential Scenario
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    2016-Barbarossa-Kuttler-Mathematical Modeling of Bacteria Communication in Continuous Cultures
    This paper presents a simple system of delay differential equations (DDEs) for quorum sensing of Pseudomonas putida with one positive feedback plus one (delayed) negative feedback mechanism.
    gene regulatory networkschemostatbifurcationNumerical Simulationquorum sensing
    Potential Scenario
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    2014-Michael_Monagan-The Mortgage Payment Problem Approximating a Discrete Process with a Differential Equation
    In this article and a subsequent article I will give two non-standard examples that I've found helpful. The one presented here is a first order linear system. Second order systems and non-linear systems.
    compartmentheatinghouse
    Potential Scenario
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    2011-Lucas_Pulley-Analyzing Predator-Prey Models Using Systems of Ordinary Linear Differential Equations
    This research focused on applying biological mathematics to analyzing predation relationships, especially the relationship between the Canadian Lynx and the Snowshoe Hare.
    simulationpredator-preyLotka-VolterrapopulationCanadian LynxSnowshoe Harecritical values
    Potential Scenario
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    1975-David_Burghes-Population dynamics An introduction to differential equations
    In this paper a number of population models, which lead to differential equations, are derived. First-order variables separable equations are formulated from the Malthusian population model and its extension to include crowding effects.
    fishpredator-preylogisticpopulationdelaylag