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Views
Date
Relevance
Potential Scenario
140
views
80
downloads
0
comments
2017-ASHP-Intro to Pharmacokinetics and Pharmacodynamics
This is the introductory Lesson 1 in an online set of materials to introduce Pharmacokinetics and Pharmacodynamics.
absorption
compartment
bloodstream
plasma
pharmacokinetics
pharmacodynamics
therapeutic concentration range
drug disposition
drug response
Potential Scenario
196
views
70
downloads
0
comments
2015-Valerie_Billard-Pharmacokinetic-pharmacodynamic relationship of anesthetic drugs - from modeling to clinical use
The purpose of this short review is to describe the basis of pharmacokinetics and modeling, the concentration-effects relationship, and drug interactions modeling to offer to anesthesiologists and non-anesthesiologists an overview of the rules to...
anesthesia
pharmacokinetics
pharmacodynamic
anesthetic
Potential Scenario
133
views
56
downloads
0
comments
2017-ASHP-Intro to Pharmacokinetics and Pharmacodynamics
This is the introductory Lesson 1 in an online set of materials to introduce Pharmacokinetics and Pharmacodynamics.
absorption
compartment
bloodstream
plasma
pharmacokinetics
drug
pharmacodynamics
Potential Scenario
182
views
50
downloads
0
comments
2012-Jambhekar-Breen-Extravascular Routes Of Drug Administration in Basic Pharamacokinetics
This provides an excellent step-by-step of the physiology, construction of model, and notions like peak concentration as well as issues like lag time.
concentration
physiology
drugs
lag time
Extravascular
Pharamacokinetics
peak time
Potential Scenario
136
views
73
downloads
0
comments
2016-Erno_Keszei-Chemical Kinetics for Beginners
The most important goal of kinetic research is the identification and characterisation of elementary molecular events which make possible the transformation of reactants into products.
kinetics
zeroth order reaction
first order reaction
second order reaction
reaction rates
third order reaction
Potential Scenario
281
views
70
downloads
0
comments
1968-Wagner-Aghajanian-Bing-Correlation of performance test scores with tissue concentration of lysergic acid diethylamide
This paper offers a two compartment model of lysergic acid diethylamide (LSD) in volunteer students and through parameter estimation models the amount of LSD in the tissue after its initial administration through the plasma.
LSD
correlation coefficient
compartment model
lysergic acid diethylamide
performance
test score
tissue concentration
Modeling Scenario
310
views
228
downloads
0
comments
1-085-DrugBolus-ModelingScenario
Given data on the concentration of a drug in the plasma of a human in mg/L at certain time intervals in hours can we determine the rate at which the drug leaves the plasma as well as the initial amount administered in a intravenous bolus of the drug?
concentration
sum of square errors
bolus
drug
rate constant
administer
Modeling Scenario
377
views
441
downloads
0
comments
1-011A-Kinetics-ModelingScenario
We help students see the connection between college level chemistry course work and their differential equations coursework. We do this through modeling kinetics, or rates of chemical reaction.
kinetics
Law of Mass Action
fitting
order of reaction
chemical reaction
Potential Scenario
280
views
79
downloads
0
comments
2014-Blomhøj-EtAl-Compartment models
An overview of compartment models with many rich illustrations and much attention to various numerical methods in solutions of the resulting differential equations using Matlab. Also included is a section on the limitations of compartment models.
concentration
kinetics
physiology
compartment
salt
tank
balance
reactions
mink
bathtub
Modeling Scenario
266
views
387
downloads
0
comments
1-094-SteepingTea-ModelingScenario
We provide photographs of steeping process for a tea steeped in hot water. Students build a differential equation model for the steeping process and do parameter estimation using the color of our tea as a way to measure relative concentration.
concentration
Surface Area
color
Newton's Law of Cooling
tea
sugar
Potential Scenario
172
views
44
downloads
0
comments
2015-Sivakumar-EtAl-Approximate Analytical Expression of Concentrations in a Kinetic Model for Biogas Generation from Banana Waste
The initial value problem in a kinetic model for biogas generation from banana waste is discussed. The model involves the system of non-linear differential equations which has variety of non-linear rate function.
chemical kinetics
Michaelis-Menten kinetics
anaerobic digestion
acidogenic steps
banana
methanogenic steps
wastes
Potential Scenario
161
views
68
downloads
0
comments
1972-R_C_Rothermel-A Mathematical Model for Predicting Fire Spread in Wildland Fuels
The development of a mathematical model for predicting rate of fire spread and intensity applicable to a wide range of wildland fuels is presented from the conceptual stage through evaluation and demonstration of results to hypothetical fuel models.
prediction
forest fire
fire management
fire spread
fuel
Potential Scenario
112
views
62
downloads
0
comments
2015-Peter_Cumber-Waggling pendulums and visualization in mechanics
This article describes an equation of motion for a waggling pendulum.
resonance
inverted pendulum
mechanics
damped pendulum
Potential Scenario
119
views
51
downloads
0
comments
2004-Aldo_Rescigno-On the use of pharmacokinetic models
In this paper I will define in a simple and logical way a set of useful pharmacokinetic parameters and show how their estimation depends on the assumed model.
compartment
steady state
pharmacokinetics
volume distribution
Potential Scenario
306
views
54
downloads
0
comments
1976-JG-Wagner-Computers in pharmacokinetics
This is a seminal paper in pharmacokinetics in which the author introduces historic notions and approaches. As can be seen from the abstract there is a variety of material here.
kinetics
computer
parameters
Pharmacology
drugs
pharmacokinetics
Potential Scenario
142
views
47
downloads
0
comments
2008-Huangi-Lu-Modeling long-term longitudinal HIV dynamics with applications to an AIDS clinical studyÂ
To better understand the factors responsible for the virological failure, this paper develops the mechanism-based nonlinear differential equation models for characterizing long-term viral dynamics with ARV therapy.
longitudinal data
AIDS
antiretroviral drug therapy
Bayesian nonlinear mixed-effects
time-varying drug efficacy
HIV dynamics
Modeling Scenario
243
views
123
downloads
0
comments
3-040-FirstPassageTime-ModelingScenario
We apply the notions of dampedness to second order, linear, constant coefficient, homogeneous differential equations used to model a spring mass dashpot system and introduce the notion of first passage time through 0 value with several applications.
oscillator
damped
underdamped
first passage
first passage time
spring mash dashpot
Potential Scenario
184
views
89
downloads
0
comments
2015-Boggess-EtAl-Mathematical Modeling in Ecology - Simulating the Reintroduction of the Extinct Passenger Pigeon
To determine under which conditions a Passenger Pigeon could survive a reintroduction into a natural habitat, we used two types of models.
simulation
agent-based modeling
allee_effect
Passenger Pigeons
forest envirnoment
Holling Type III functional response
Bio-energetics
tree distributions
Potential Scenario
146
views
40
downloads
0
comments
2012-José_Sérgio_Domingues-Gompertz Model - Resolution and Analysis for Tumors
The main objective of this paper is to use the Gompertz equation in order to study the development of blood irrigated solid tumors, using parameters defined in some important bibliographic references about the mathematical modelling of tumors.
tumor
Gompertz equation
growth tumor
Potential Scenario
223
views
52
downloads
0
comments
1999-Khorasheh-Ahmadi-Gerayeli-Application of Direct Search Optimization for Pharmacokinetic Parameter Estimation
For simple pharmacokinetic compartmental models, analytical solution to the governing differential equations provide a mean to evaluate the associated rate constants. Such methods, however, can not be used used for more complex multi-compartment...
sum of square errors
least squares
pharmacokinetics
lineteics
compartmental models
direct search
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