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Potential Scenario
174
views
65
downloads
0
comments
1964-Aghajanian-Bing-Persistence Of LSD In Plasma In Human Subjects
Two micrograms per kilogram of LSD-25 was administered intravenously to five normal human subjects. The concentration of[ drug in plasma was determined serially over the subsequent 8 hours. We model this.
LSD
score
plasma
lysergic acid diethylamide
human subjuects
Potential Scenario
160
views
48
downloads
0
comments
1969-Carl_Metzler-A mathematical model for the pharmacokinetics of LSD effect
Contains data on performance scores vs. plasma levels of LSD in human tissues.
LSD
testing
pharmacokinetics
performance
plasma level
Potential Scenario
281
views
70
downloads
0
comments
1968-Wagner-Aghajanian-Bing-Correlation of performance test scores with tissue concentration of lysergic acid diethylamide
This paper offers a two compartment model of lysergic acid diethylamide (LSD) in volunteer students and through parameter estimation models the amount of LSD in the tissue after its initial administration through the plasma.
LSD
correlation coefficient
compartment model
lysergic acid diethylamide
performance
test score
tissue concentration
Potential Scenario
200
views
90
downloads
0
comments
1957-Axelrod_ Brady_Witkop_Evarts-The Distribution and Metabolism of Lysergic Acid Diethylamide
The development of a specific and sensitive method for the estimation of LSD in biological materials has enabled us to study the tissue distribution, excretion, rate of biotransformation, and metabolism of the drug, as well as the subcellular...
mathematical model
data
LSD
Metabolism
bloodstream
lysergic acid diethylamide
distribution
Modeling Scenario
1181
views
5487
downloads
0
comments
5-001-LSD-ModelingScenario
We describe the use of a two compartment model of a linear system of first order linear differential equations to model lysergic acid diethylamide (LSD) in the body. We provide the data from the literature.
LSD
Spanish
compartment
pharmacokinetics
lysergic acid diethylamide
Potential Scenario
208
views
89
downloads
0
comments
1971-Carl_Metzler-Usefulness Of Two Compartment Open Model In Pharmacokinetics
Compartment models are widely used in pharmaceutical research to quantitate the kinetics of absorption, distribution, metabolism and excretion of a drug. In this article two applications of the two compartment open model are discussed.
LSD
compartment
pharmacokinetics
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