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Views
Date
Relevance
Potential Scenario
103
views
38
downloads
0
comments
2012-Shargel-Yu-AccessPharmacy-Applied Biopharmaceutics and Pharmacokinetics
Step by step formation of drug absorption models is shown with many good graphics of system and plots. Solutions are offered but no solution methods are shown.
Michaelis-Menten
Enzyme
substrate
compartment
pharmacokinetics
rate constant
urinary data
absorption rate
Potential Scenario
150
views
50
downloads
0
comments
2011-Nguyen-Shi-Modeling the absorption circulation and metabolism of tirapazamine
This apparently is a student project and it develops the kinetic model, uses Matlab for numerical solution, analytic solution and numerical solution.
absorption
Michaelis-Menten
Metabolism
drug metabolism
circulation
Potential Scenario
182
views
50
downloads
0
comments
2012-Jambhekar-Breen-Extravascular Routes Of Drug Administration in Basic Pharamacokinetics
This provides an excellent step-by-step of the physiology, construction of model, and notions like peak concentration as well as issues like lag time.
concentration
physiology
drugs
lag time
Extravascular
Pharamacokinetics
peak time
Potential Scenario
134
views
52
downloads
0
comments
2019-Radulescu-Lundgren-A_pharmacokinetic_model_of_lead_absorption_and_calcium_competitive_dynamics
We build and analyze a compartmental model of lead pharmacokinetics, focused specifically on addressing neurotoxicity.
QUBES Leadership Team
parameters
absorption
bifurcation
pharmacokinetics
calcium
cognitive decline
Potential Scenario
208
views
89
downloads
0
comments
1971-Carl_Metzler-Usefulness Of Two Compartment Open Model In Pharmacokinetics
Compartment models are widely used in pharmaceutical research to quantitate the kinetics of absorption, distribution, metabolism and excretion of a drug. In this article two applications of the two compartment open model are discussed.
LSD
compartment
pharmacokinetics
Modeling Scenario
1181
views
5487
downloads
0
comments
5-001-LSD-ModelingScenario
We describe the use of a two compartment model of a linear system of first order linear differential equations to model lysergic acid diethylamide (LSD) in the body. We provide the data from the literature.
LSD
Spanish
compartment
pharmacokinetics
lysergic acid diethylamide
Potential Scenario
133
views
56
downloads
0
comments
2017-ASHP-Intro to Pharmacokinetics and Pharmacodynamics
This is the introductory Lesson 1 in an online set of materials to introduce Pharmacokinetics and Pharmacodynamics.
absorption
compartment
bloodstream
plasma
pharmacokinetics
drug
pharmacodynamics
Potential Scenario
140
views
80
downloads
0
comments
2017-ASHP-Intro to Pharmacokinetics and Pharmacodynamics
This is the introductory Lesson 1 in an online set of materials to introduce Pharmacokinetics and Pharmacodynamics.
absorption
compartment
bloodstream
plasma
pharmacokinetics
pharmacodynamics
therapeutic concentration range
drug disposition
drug response
Modeling Scenario
208
views
239
downloads
0
comments
5-020-ParacetamolAbsorption-ModelingScenario
We offer drug absorption data on paracetamol, an analgesic pain reliever, for two different sets of patients, vegetarian and non-vegetarian. Students build a two compartment model for plasma and non-plasma (tissue) compartments of human patients.
paracetamol
analgesic
vegetarian
non-vegetarian
Potential Scenario
143
views
46
downloads
0
comments
2005-Minna_Wedenberg-Pharmacokinetic modeling of gastric emptying
The development of new drug substances is a complex, time consuming and expensive process. Reducing the time for drug development and avoiding late termination of candidate drugs are important challenges for the pharmaceutical industry.
paracetamol
pharmacokinetics
stomach
small intestine
sulfapyridine
Modeling Scenario
650
views
394
downloads
0
comments
5-011-ModelingIbuprofren-ModelingScenario
We consider modeling of data from a clinical experiment administered as oral doses of 400 mg ibuprofen, an analgesic pain reliever. Concentrations of ibuprofen in the serum/plasma of the subjects were recorded after the initial ingestion of the...
data
AIC
Akaike Information Criterion
absorption
sum of square errors
compartment model
ibuprofen
delay
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