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    Modeling Scenario
    264

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    215

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    6-010-SocialCampaign-ModelingScenario
    The epidemic modeling problem is formulated as a system of three nonlinear, first order differential equations in which three compartments (S, I, and R) of the population are linked.
    diseasegrowth rateJudgment and Decision MakingSIR modelinfections diseasesocial campaignrecovery ratedelay timejoining processquitting processexponential distribution
    Article or Presentation
    163

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    54

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    2009-Agnes_Rash-Brian_Winkel-Birth_and_Death_Process_Modeling_Leads_to_the_Poisson_Distribution
    In this paper there are details of development of the general birth and death process from which we can extract the Poisson process as a special case.
    ProbabilityMeanPoisson processbirth and death processinfinite number of differential equations
    Potential Scenario
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    80

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    2014-Wang-EtAl-Estimating Mixed-Effects Differential Equation Models
    When multiple replicates of measurements are available for the dynamic process, it is of great interest to estimate mixed-effects in the ODE model for the process. We propose a semiparametric method to estimate mixed-effects ODE models.
    pharmacokineticsdynamic modelssmoothingsplinemixed-effects modelsHiV combination therapy
    Modeling Scenario
    399

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    153

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    1-001s-StochasticMDeathImmigration-ModelingScenario
    We develop a mathematical model of a death and immigration process using m&ms as a stochastic process with the help of probability generating functions (pgf). We start with 50 m&ms in a bag.
    simulationdatalogisticimmigrationstochasticdeathfitting
    Potential Scenario
    141

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    67

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    2017-Allali-EtAl-Mathematical Modeling of the Adaptive Immune Responses in the Early Stage of the HBV Infection
    The aim of this paper is to study the early stage of HBV infection and impact delay in the infection process on the adaptive immune response, which includes cytotoxic T-lymphocytes and antibodies.
    logisticHBV infectionadaptive immunie responseT-lymphocytes
    Modeling Scenario
    429

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    119

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    6-067-LotkaVolterra-ModelingScenario
    This modeling scenario guides students through the process of fitting the Lotka-Volterra model of two differential equations to a real time series observational data. Students use the capabilities of R and R studio.
    time seriesdatacompetitionLotka-Volterramodel fittingpredictiongauseRexperimental
    Modeling Scenario
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    4065

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    1-038-Ebola-ModelingScenario
    Students will use data published by the World Health Organization to model the 2014 outbreak of the Ebola virus in West Africa. We begin with a simple exponential growth model and move through the modeling process to the logistic growth model.
    population dynamicsdata analysisexponential growthEbolalogisticepidemic
    Modeling Scenario
    298

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    179

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    5-010-DNADegradation-ModelingScenario
    We ask students to use the system of first order linear differential equations given in a source paper and estimates of the data from laboratory procedures from a plot to estimate the parameters and complete the modeling process.
    DNA\kinetisplasmaratpharmacokinetis
    Modeling Scenario
    333

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    123

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    1-131-CaffeineElimination-ModelingScenario
    We model the concentration of caffeine eliminated from the human body at a rate proportional to the concentration. This is a ``first-order reaction'' in the language of pharmacokinetics -- the study of how drugs move in the body.
    caffeineeliminationpharmacokineticsdrug
    Potential Scenario
    180

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    52

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    0

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    1997-Bonnie_Shulman-Using Original Sources to Teach the Logistic Equation
    This Module uses original data, diagrams, and texts from three original sources to develop the logistic model of growth in natural systems with limited resources.
    logisticoriginal source
    Modeling Scenario
    330

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    481

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    1-033-SouthernBarbeque-ModelingScenario
    We offer raw data collected from two thermometers used in the smoking process of Southern barbecue. One thermometer measures the temperature inside of the smoke chamber and the other measures the internal temperature of the meat.
    nonlinear regressionlogisticNewton's Law of Cooling-Warmingbarbecue
    Modeling Scenario
    314

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    472

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    1-065-AlgalBlooms-ModelingScenario
    This modeling scenario investigates the massive algal blooms that struck Lake Chapala, Mexico, starting in 1994.
    direction fieldstool:dfieldalgaeharmful algae bloomspopulationcompartmentLake Chapala
    Potential Scenario
    135

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    51

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    2007-Zenker-Rubin-Clermont-From inverse problems in mathematical physiology to quantitative differential diagnoses
    The improved capacity to acquire quantitative data in a clinical setting has generally failed to improve outcomes in acutely ill patients, suggesting a need for advances in computer-supported data interpretation and decision making.
    physiologyinverse problem
    Potential Scenario
    154

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    56

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    2006-Cooke-Elderkin-Huang-Predator-Prey interactions with delays due to juvenile maturation
    This paper focuses on predator-prey models with juvenile/mature class structure for each of the predator and prey populations in turn, further classified by whether juvenile or mature individuals are active with respect to the predation process.
    predator-preyhost-parasitebifurcationage structrematuration delay
    Potential Scenario
    143

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    46

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    2005-Minna_Wedenberg-Pharmacokinetic modeling of gastric emptying
    The development of new drug substances is a complex, time consuming and expensive process. Reducing the time for drug development and avoiding late termination of candidate drugs are important challenges for the pharmaceutical industry.
    paracetamolpharmacokineticsstomachsmall intestinesulfapyridine
    Article or Presentation
    130

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    54

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    2011-Carl_Leinbach-Beyond_Newton_law_of_cooling_estimation_of_time_since_death
    The estimate of the time since death. Thus, the time of death is strictly that, an estimate. However, the time of death can be an important piece of information in some coroner’s cases, especially those that involve criminal or insurance...
    Newton's Law of Coolingtime of deathdouble exponentialcoroner
    Modeling Scenario
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    183

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    1-046-GoingViral-ModelingScenario
    Students participate in a simulation of the spread of a viral disease in the classroom and model the process with a logistic differential equation. The simulation uses random numbers and the entire class participates.
    simulationmathematical modeldatalogisticrandom number generatorfittingrandom process
    Potential Scenario
    200

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    2017-D_Goulet-Modeling, Simulating, and Parameter Fitting of Biochemical Kinetic Experiments
    In many chemical and biological applications, systems of differential equations containing unknown parameters are used to explain empirical observations and experimental data. The differential equations are typically nonlinear.
    optimizationBiochemistrysensitivity analysischromatographymass actioncluster analysisconservation lawsdimerizationestrogen receptor protein
    Potential Scenario
    190

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    45

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    2013-Alicia_Caldwell-Students Rise to the Challenge of Modeling Yeast Growth Despite Sour Hiccups from Imperfect Data
    This paper describes a lab in which students in an Applied Mathematics in Biology course observe the growth of Saccharomyces cerevisiae, a yeast strain, in differing sugar concentrations for use in learning modeling.
    Saccharomyces cerevisiaelogisticyeastdeathgrowthsugaralcohol
    Potential Scenario
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    57

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    2003-Yildirim-Mackey-Feedback Regulation in the Lactose Operon
    A mathematical model for the regulation of induction in the lac operon in Escherichia coli is presented.
    mRNAlactoselactose operonfeedback regulation