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    Potential Scenario
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    2015-Zhang-EtAl-On the Selection of ODE Models with Application to Predator-Prey Dynamical Models
    We propose a computationally inexpensive approach that employs statistical estimation of the full model, followed by a combination of a least squares approximation (LSA) and the adaptive Lasso.
    least-squares approximationSpline modelingMonte Carlo simulationsvariable selectionadaptive LASSO
    Potential Scenario
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    1975-Rodda-Sampson-Smith-The One-Compartment Open Model Parameter Estimation
    A new estimation procedure is proposed for estimating the parameters of the simplest pharmacokinetic model, the one-compartment open model.
    compartment modelpharmacokineticsnonlinear estimationone compartment model
    Potential Scenario
    223

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    1999-Khorasheh-Ahmadi-Gerayeli-Application of Direct Search Optimization for Pharmacokinetic Parameter Estimation
    For simple pharmacokinetic compartmental models, analytical solution to the governing differential equations provide a mean to evaluate the associated rate constants. Such methods, however, can not be used used for more complex multi-compartment...
    sum of square errorsleast squarespharmacokineticslineteicscompartmental modelsdirect search
    Potential Scenario
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    2017-Justin_Krueger-Parameter Estimation Methods for Ordinary Differential Equation Models with Applications to Microbiology
    We demonstrate the feasibility of principal differential analysis using simulation studies and then apply the method to intestinal and vaginal microbiota data.
    microbiologyLotka Volterrramicrobiota
    Potential Scenario
    119

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    53

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    2008-Brewer-EtAl-Fitting ordinary differential equations to short time course data
    In this paper, we present a survey of existing algorithms and describe the main approaches. We also introduce and evaluate a new efficient technique for estimating ODEs linear in parameters particularly suited to situations where noise levels are...
    time seriesEvaluation SPLINEgeneleast squaresbifurcation
    Potential Scenario
    769

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    72

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    2013-Fathalla_Rihan-Delay Differential Equations in Biosciences - Parameter estimation and sensitivity analysis
    This is a review article to show that delay differential models have a richer mathematical framework (compared with models without memory or after-effects) and a better consistency with biological phenomena such dynamical diseases and cell growth...
    epidemiologysensitivityImmunologyphysiologyRK-methodstime-lags
    Modeling Scenario
    242

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    447

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    6-026-IsleRoyaleModeling-ModelingScenario
    The primary aim of this project is to draw a connection between differential equations and vector calculus, using population ecology modeling as a vehicle.
    ecologyoptimizationpredator-preypopulationvector calculusLagrange multipliersleast squaresIslel Royale
    Modeling Scenario
    223

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    255

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    6-029-TumorGrowth-ModelingScenario
    This modeling scenario guides a student familiar with single ordinary differential equation (ODE) models towards the development of a more complex system of two ODEs for describing the evolution of tumor growth over time.
    Pop_Growth Pilotlogisticcomparmenttumorsynthetic datasum of squares error
    Potential Scenario
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    48

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    1984-W_Brunner-D__Focht-Deterministic Three-Half-Order Kinetic Model for Microbial Degradation
    The kinetics of mineralization of carbonaceous substrates has been explained by a deterministic model which is applicable to either growth or nongrowth conditions in soil.
    kineticsnonlinear regressionsum of square errorsMonodlinearizemineralizationsubstratescarbonaceous
    Modeling Scenario
    260

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    185

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    1-130-AspirinAbsorption-ModelingScenario
    We model the amount of aspirin absorbed by the human body at a constant rate. This is a ``zero-order reaction'' in the language of pharmacokinetics -- the study of how drugs move in the body.
    pharmacokineticsdrugaspirin
    Modeling Scenario
    275

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    133

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    1-143-PopulationModelVariationsMATLAB-ModelingScenario
    Students will walk through a detailed derivation and review of basic population models (exponential and logistic) to create and understand variations of those models.
    population dynamicsecologylogistic growthbifurcation theoryslope fieldsextinctionharvestingqualitative analysisstocking
    Potential Scenario
    154

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    62

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    2007-Mogen_Steffensen-Differential Equations in Finance and Life Insurance
    The mathematics of finance and the mathematics of life insurance were always intersecting. Life insurance contracts specify an exchange of streams of payments between the insurance company and the contract holder.
    financedisabilitylife insurancemortalityinsuraneThiele’s equationBlack-Scholes equation
    Potential Scenario
    174

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    45

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    2017-Helen-Byrne-Further Mathematics Biology
    These studies will be in the context of ecological, biological and biochemical applications.
    epidemicschemotaxisenzyme-substrateion channelsnerve pulsesgene proagationtumour
    Potential Scenario
    226

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    2014-Vance-Eads-Sensitivity Analysis of a Three-Species Nonlinear Response Omnivory Model with Predator Stage Structure
    We investigate a three-species nonlinear response omnivory model incorporating stage structure in the top predator. The model consists of four coupled ordinary differential equations involving fourteen parameters.
    stage structuresensitivity analysismortalityomnivoreomnivory modelsearch rates
    Potential Scenario
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    46

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    2012-Greer-Palin-Students in Differential Equations and Epidemiology Model a Campus Outbreak of pH1N1
    We describe a semester-long collaboration between a mathematics class and a biology class. Students worked together to understand and model the trajectory of the pandemic H1N1, pH1N1, outbreak across campus in fall 2009.
    H1N1pandemicspreadoutbreakpH1N1
    Modeling Scenario
    228

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    340

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    6-019-EnablingEpidemicExploration-ModelingScenario
    We became aware of several interesting possibilities for a modeling opportunity with data and we invited you to explore the several routes to parameter estimation in a SIR model with respect to the data offered.
    Akaike Information CriterionMichaelis-Mentenepidemicsaturationgradientleast sum of square errors
    Potential Scenario
    148

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    56

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    2018-Adeniji-EtAl-InverseProblemHolling-TannerModel
    We consider the inverse problem of parameter identification of nonlinear system of ODEs for a specific case of complete information about solution of the Holling-Tanner model for finite number of points for the finite time interval.
    goal functionabsolute error curvesinvers methodholling-Tanner model
    Potential Scenario
    141

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    48

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    2012-Nokkaew-EtAl-Estimation of Algae Growth Model Parameters by a Double Layer Genetic Algorithm
    This paper presents a double layer genetic algorithm (DLGA) to improve performance of the information-constrained parameter estimations.
    optimizationalgae growthgenetic algorithmssimulated dataconvergence of parameters
    Potential Scenario
    229

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    57

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    2009-Schaffer-Bronnikova-Controlling malaria
    The present paper reviews potential control strategies from the viewpoint of mathematical epidemiology.
    epidemiologymalariabifurcationmosquitotransgenic mosquitoes
    Article or Presentation
    127

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    64

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    1992-Emelie_Kenney-Differential_equations_and_the_AIDS_epidemic
    This paper describes a lecture for Calculus II students in which the Acquired Immune Deficiency Syndrome was used to motivate study of first-order linear differential equations and the derivative as a rate of change.
    datafirst orderparameterAIDS