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    Potential Scenario
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    1975-Rodda-Sampson-Smith-The One-Compartment Open Model Parameter Estimation
    A new estimation procedure is proposed for estimating the parameters of the simplest pharmacokinetic model, the one-compartment open model.
    compartment modelpharmacokineticsnonlinear estimationone compartment model
    Potential Scenario
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    2018-Adeniji-EtAl-InverseProblemHolling-TannerModel
    We consider the inverse problem of parameter identification of nonlinear system of ODEs for a specific case of complete information about solution of the Holling-Tanner model for finite number of points for the finite time interval.
    goal functionabsolute error curvesinvers methodholling-Tanner model
    Potential Scenario
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    2018-Joseph-EtAl-A Nonlinear differential equation model of Asthma effect of environmental pollution using LHAM
    In this paper, we investigated a nonlinear differential equation mathematical model to study the spread of asthma in the environmental pollutants from industry and mainly from tobacco smoke from smokers in different type of population.
    asthmatobacco smokeLiao’s Homotopy analysis Method (environmental pollutants
    Potential Scenario
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    2014-Vance-Eads-Sensitivity Analysis of a Three-Species Nonlinear Response Omnivory Model with Predator Stage Structure
    We investigate a three-species nonlinear response omnivory model incorporating stage structure in the top predator. The model consists of four coupled ordinary differential equations involving fourteen parameters.
    stage structuresensitivity analysismortalityomnivoreomnivory modelsearch rates
    Potential Scenario
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    2015-Zhang-EtAl-On the Selection of ODE Models with Application to Predator-Prey Dynamical Models
    We propose a computationally inexpensive approach that employs statistical estimation of the full model, followed by a combination of a least squares approximation (LSA) and the adaptive Lasso.
    least-squares approximationSpline modelingMonte Carlo simulationsvariable selectionadaptive LASSO
    Potential Scenario
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    2003-Yildirim-Mackey-Feedback Regulation in the Lactose Operon
    A mathematical model for the regulation of induction in the lac operon in Escherichia coli is presented.
    mRNAlactoselactose operonfeedback regulation
    Modeling Scenario
    288

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    234

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    1-078-MonodGrowthModel-ModelingScenario
    Students model growth of bacteria E. coli in a limiting nutrient environment using data from a historical study.
    bacterianutrient cyclesgrowthMonodconsumption
    Potential Scenario
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    2017-Justin_Krueger-Parameter Estimation Methods for Ordinary Differential Equation Models with Applications to Microbiology
    We demonstrate the feasibility of principal differential analysis using simulation studies and then apply the method to intestinal and vaginal microbiota data.
    microbiologyLotka Volterrramicrobiota
    Article or Presentation
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    526

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    2020-TeachingModule-ModelingNonlethalInfluenzaEpidemic
    We discuss the modeling efforts and tools for success in modeling the spread of nonlethal influenza in an English boarding school
    moduleepidemicboarding schoolTeaching Module
    Potential Scenario
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    2012-Murray_Bourne-Modeling fish stocks
    Discusses many models of harvesting and consequences.
    fishlogisticmanagementsusustainable developmentharvestfish stockoverpopulatedunsustainable
    Potential Scenario
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    2017-D_Goulet-Modeling, Simulating, and Parameter Fitting of Biochemical Kinetic Experiments
    In many chemical and biological applications, systems of differential equations containing unknown parameters are used to explain empirical observations and experimental data. The differential equations are typically nonlinear.
    optimizationBiochemistrysensitivity analysischromatographymass actioncluster analysisconservation lawsdimerizationestrogen receptor protein
    Potential Scenario
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    2007-Choisy-Guégan-Rohani-Mathematical Modeling of Infectious Diseases Dynamics
    After presenting general notions of mathematical modeling (Section 22.2) and the nature of epidemiological data available to the modeler (Section 22.3), we detail the very basic SIR epidemiological model (Section 22.5).
    stochasticSIR modeldeterministicincubationinfectives
    Potential Scenario
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    1999-Meyer-Ausubel-Carrying Capacity-A Model with Logistically Varying Limits
    This paper extends the logistic equation to simple growth model with a logistically increasing carrying capacity. This is applied to human population situations in several countries with fits to data.
    population dynamicsparameter estimationlimited growthgrowthlogisitic
    Modeling Scenario
    311

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    1-018-LogisticPopModel-ModelingScenario
    We offer artificial (toy) and historical data on limited growth population situations in the study of protozoa and lead students through several approaches to estimating parameters and determining the validity of the logistic model in these...
    data analysisparameter estimationlogisticCiliate protozoapopulationlimited growthparameciaGause
    Potential Scenario
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    2008-Huangi-Lu-Modeling long-term longitudinal HIV dynamics with applications to an AIDS clinical study 
    To better understand the factors responsible for the virological failure, this paper develops the mechanism-based nonlinear differential equation models for characterizing long-term viral dynamics with ARV therapy.
    longitudinal dataAIDSantiretroviral drug therapyBayesian nonlinear mixed-effectstime-varying drug efficacyHIV dynamics
    Potential Scenario
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    2008-Abramson-Mathematical modeling of the spread of infectious diseases
    These are informal notes, mostly based on the bibliography listed at the end and on recent papers in the field. The practical use of these models is based on the fact that they can be kept realistic enough.
    infectious diseasebibliographyepidemiccowpoxsmallpoxcomplex networksspread disease
    Potential Scenario
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    2014-Murillo-EtAl-Vertical Transmission in a Two-Strain Model of Dengue Fever
    The model is used to show that lower transmission rates of DENV-2 Asian are sufficient for displacing DENV-2 American in the presence of vertical transmission.
    Peruvector-host modeldengueepidemmiologyvertical transmission
    Potential Scenario
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    2014-Wang-EtAl-Estimating Mixed-Effects Differential Equation Models
    When multiple replicates of measurements are available for the dynamic process, it is of great interest to estimate mixed-effects in the ODE model for the process. We propose a semiparametric method to estimate mixed-effects ODE models.
    pharmacokineticsdynamic modelssmoothingsplinemixed-effects modelsHiV combination therapy
    Potential Scenario
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    2013-Alicia_Caldwell-Students Rise to the Challenge of Modeling Yeast Growth Despite Sour Hiccups from Imperfect Data
    This paper describes a lab in which students in an Applied Mathematics in Biology course observe the growth of Saccharomyces cerevisiae, a yeast strain, in differing sugar concentrations for use in learning modeling.
    Saccharomyces cerevisiaelogisticyeastdeathgrowthsugaralcohol
    Modeling Scenario
    228

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    340

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    6-019-EnablingEpidemicExploration-ModelingScenario
    We became aware of several interesting possibilities for a modeling opportunity with data and we invited you to explore the several routes to parameter estimation in a SIR model with respect to the data offered.
    Akaike Information CriterionMichaelis-Mentenepidemicsaturationgradientleast sum of square errors