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Downloads
Views
Date
Relevance
Potential Scenario
129
views
48
downloads
0
comments
2010-Shianga-EtAl-Computational model of the human glucose-insulin regulatory system
A computational model of insulin secretion and glucose metabolism for assisting the diagnosis of diabetes mellitus in clinical research is introduced. The
glucose tolerance test
sum of squared residuals
multiple shooting method
cost function
Potential Scenario
146
views
51
downloads
0
comments
1991-JR_Lobry-P_Flandois-Comparison of Monod's Growth Model Parameters from the Same Data Set
The paper obtains the parameters in Monod's Growth model using a minimization of the sum of square errors with a given data set and obtains confidence intervals
Confidence intervals
sum of square errors
linearization
growth
Modo Growth model
Potential Scenario
158
views
48
downloads
0
comments
1984-W_Brunner-D__Focht-Deterministic Three-Half-Order Kinetic Model for Microbial Degradation
The kinetics of mineralization of carbonaceous substrates has been explained by a deterministic model which is applicable to either growth or nongrowth conditions in soil.
kinetics
nonlinear regression
sum of square errors
Monodlinearize
mineralization
substrates
carbonaceous
Potential Scenario
223
views
52
downloads
0
comments
1999-Khorasheh-Ahmadi-Gerayeli-Application of Direct Search Optimization for Pharmacokinetic Parameter Estimation
For simple pharmacokinetic compartmental models, analytical solution to the governing differential equations provide a mean to evaluate the associated rate constants. Such methods, however, can not be used used for more complex multi-compartment...
sum of square errors
least squares
pharmacokinetics
lineteics
compartmental models
direct search
Potential Scenario
182
views
50
downloads
0
comments
2012-Jambhekar-Breen-Extravascular Routes Of Drug Administration in Basic Pharamacokinetics
This provides an excellent step-by-step of the physiology, construction of model, and notions like peak concentration as well as issues like lag time.
concentration
physiology
drugs
lag time
Extravascular
Pharamacokinetics
peak time
Modeling Scenario
650
views
394
downloads
0
comments
5-011-ModelingIbuprofren-ModelingScenario
We consider modeling of data from a clinical experiment administered as oral doses of 400 mg ibuprofen, an analgesic pain reliever. Concentrations of ibuprofen in the serum/plasma of the subjects were recorded after the initial ingestion of the...
data
AIC
Akaike Information Criterion
absorption
sum of square errors
compartment model
ibuprofen
delay
Modeling Scenario
220
views
130
downloads
0
comments
1-009-ICUSpread-ModelingScenario
We offer students the opportunity to model the percentage of voluntary nonprofit hospitals in the United States with Intensive Care Units during the period of 1958-1974.
logistic
sum of square errors
Intensive Care Unit
hospital
spread
Modeling Scenario
223
views
255
downloads
0
comments
6-029-TumorGrowth-ModelingScenario
This modeling scenario guides a student familiar with single ordinary differential equation (ODE) models towards the development of a more complex system of two ODEs for describing the evolution of tumor growth over time.
Pop_Growth Pilot
logistic
comparment
tumor
synthetic data
sum of squares error
Modeling Scenario
1271
views
976
downloads
0
comments
1-030-EyeModel-ModelingScenario
We offer a mathematical modeling experience using differential equations to model the volume of an intraocular gas bubble used by ophthalmologists to aid the healing of a surgically repaired region of the retina.
retinal surgery
Akaike Information Criterion
Spanish
sum of square errors
surgery
retiona
ophthalmology
eye
intraocular gas bubble
Modeling Scenario
228
views
340
downloads
0
comments
6-019-EnablingEpidemicExploration-ModelingScenario
We became aware of several interesting possibilities for a modeling opportunity with data and we invited you to explore the several routes to parameter estimation in a SIR model with respect to the data offered.
Akaike Information Criterion
Michaelis-Menten
epidemic
saturation
gradient
least sum of square errors
Modeling Scenario
310
views
228
downloads
0
comments
1-085-DrugBolus-ModelingScenario
Given data on the concentration of a drug in the plasma of a human in mg/L at certain time intervals in hours can we determine the rate at which the drug leaves the plasma as well as the initial amount administered in a intravenous bolus of the drug?
concentration
sum of square errors
bolus
drug
rate constant
administer
Potential Scenario
154
views
62
downloads
0
comments
2007-Mogen_Steffensen-Differential Equations in Finance and Life Insurance
The mathematics of finance and the mathematics of life insurance were always intersecting. Life insurance contracts specify an exchange of streams of payments between the insurance company and the contract holder.
finance
disability
life insurance
mortality
insurane
Thiele’s equation
Black-Scholes equation
Potential Scenario
136
views
66
downloads
0
comments
2017-Adolfo_Rumbos-Differential Equations and modeling
The study of any phenomenon in the physical or biological sciences, in which continuity and differentiability assumptions about the quantities in question can be made, invariably leads to a differential equation, or a system of differential...
pendulum
Lotka Volterra equations
existence
uniqueness
Article or Presentation
130
views
54
downloads
0
comments
2011-Carl_Leinbach-Beyond_Newton_law_of_cooling_estimation_of_time_since_death
The estimate of the time since death. Thus, the time of death is strictly that, an estimate. However, the time of death can be an important piece of information in some coroner’s cases, especially those that involve criminal or insurance...
Newton's Law of Cooling
time of death
double exponential
coroner
Potential Scenario
146
views
40
downloads
0
comments
2012-José_Sérgio_Domingues-Gompertz Model - Resolution and Analysis for Tumors
The main objective of this paper is to use the Gompertz equation in order to study the development of blood irrigated solid tumors, using parameters defined in some important bibliographic references about the mathematical modelling of tumors.
tumor
Gompertz equation
growth tumor
Potential Scenario
188
views
61
downloads
0
comments
2011-Mandal-EtAl-Mathematical models of malaria
The first aim of this article is to develop, starting from the basic models, a hierarchical structure of a range of deterministic models of different levels of complexity. The second is to elaborate, using some of the representative mathematical...
epidemiology
transmission
host-parasite
malaria
Ross model
Potential Scenario
1248
views
47
downloads
0
comments
2000-Erdman-Morelock-A Study of Kinetics The Estimation and Simulation of Systems of First-Order Differential Equations
This paper introduces new and old features of the SAS System for the estimation and simulation of systems of first-order differential equations with emphasis on examples in kinetics.
kinetics
SAS
compartment
pharmacokinetics
Potential Scenario
214
views
96
downloads
0
comments
2001-Smith-Moore-The SIR Model for Spread of Disease
A multiple part tour of SIR Models freely available with Maple, Mathematics, and MatLab support files at MAA site.
epidemic
SIR model
Euler's method
herd immunity
Hong Kong flu
Potential Scenario
200
views
90
downloads
0
comments
1957-Axelrod_ Brady_Witkop_Evarts-The Distribution and Metabolism of Lysergic Acid Diethylamide
The development of a specific and sensitive method for the estimation of LSD in biological materials has enabled us to study the tissue distribution, excretion, rate of biotransformation, and metabolism of the drug, as well as the subcellular...
mathematical model
data
LSD
Metabolism
bloodstream
lysergic acid diethylamide
distribution
Article or Presentation
129
views
33
downloads
0
comments
2002-Patrick_Nelson-Alan_Perelson-Mathematical_analysis_of_delay_differential _equation_models_of_HIV-1_infection
Models of HIV-1 infection that include intracellular delays are more accurate representations of the biology and change the estimated values of kinetic parameters when compared to models without delays.
delay
HIV-1
T cells
combination antiviral therapy
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