Abstract

Citation

Researchers should cite this work as follows:

• Bourne, D. (2023). 2018-David_Bourne-Pharmacokinetics – Source Material. SIMIODE, QUBES Educational Resources. doi:10.25334/F7HJ-T127

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Article Context

Description

Phamacokinetics –PHAR 7834. https://www.boomer.org/c/p4/?Loc=OUHSC33 . Accessed 29 March 2023.

This is a rich source of pharmacokinetics modeling activities and data. These are syllabus notes with homework assignments listed.

1. Online Resources
2. Background Mathematical Material
3. Biopharmaceutics and Pharmacokinetic Introduction
4. One Compartment IV Bolus
5. Analysis of Urine Data
6. Intravenous Infusion
7. Routes of Drug Administration
8. Pharmacokinetics of Oral Administration
9. Calculation of Bioavailability Parameters
10. Bioavailability Studies
11. Physiological Factors Affecting Oral Absorption
12. Physical-Chemical Factors Affecting Oral Absorption
13. Formulation Factors
14. Multiple IV Bolus Dose Administration
15. Multiple Oral Dose Administration
16. Routes of Excretion
17. Metabolism
18. Drug Distribution
19. Multi-Compartment Pharmacokinetic Models
20. Noncompartmental Analysis
21. Non-Linear Pharmacokinetic Models
22. Non-Linear Regression Analysis of Pharmacokinetic Data
23. Pharmacodynamic and Physiologically Based Pharmacokinetic Models
24. Pharmaceutical Analysis
25. Clinical Applications of Pharmacokinetics

Keywords: differential equation, model, pharmacokinetics, compartment drug, bolus, dose