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Downloads
Views
Date
Relevance
Potential Scenario
119
views
41
downloads
0
comments
1989-EY_Rodin-S_Jaques-Countercurrent Oxygen Exchange in the Swim Bladders of Deep-Sea Fish
Oxygen diffuses from lungs into blood, nutrients diffuse from intestinal tracts into blood and from blood into various cells, and waste products diffuse from cells back into blood.
fish
Cell Membrane
flow
blood
bladder
countercurrent
Modeling Scenario
438
views
189
downloads
0
comments
5-012-LipoproteinModeling-ModelingScenario
Data from a study on the amounts of low-density-lipoprotein (LDL), form of cholesterol, in blood plasma is presented. Students build, validate, and use a compartment model of the kinetic exchange of the LDL between body tissue and blood plasma.
wildlife
low-density-lipoprotein
tracer
compartment model
cholesterol
blood plasma
body tissue
Modeling Scenario
284
views
406
downloads
0
comments
5-005-Dialysis-ModelingScenario
We design a compartment model of a kidney dialysis machine and compare 3 and 9 compartments for the machine as well as determine the effect of change in one of the parameters in the model on the effectiveness to deliver quality dialysis.
countercurrent multiplier
kidney
dialysis
concurrent
compartment
Potential Scenario
115
views
33
downloads
0
comments
2012-José_Sérgio_Domingues-Gompertz Model - Resolution and Analysis for Tumors
The main objective of this paper is to use the Gompertz equation in order to study the development of blood irrigated solid tumors, using parameters defined in some important bibliographic references about the mathematical modelling of tumors.
tumor
Gompertz equation
growth tumor
Potential Scenario
162
views
45
downloads
0
comments
1996-D_Erdman-MM_Morelock-A Study of Kinetics
This paper introduces new and old features of the SAS System for the estimation and simulation of systems of first-order differential equations with emphasis on examples in kinetics.
simulation
kinetics
parameter estimation
Enzyme
substrate
savings
compartment
stomach
blood
ginseng
Potential Scenario
121
views
72
downloads
0
comments
2014-Hrydziuszko-EtAl-Mathematical Two-compartment Model of Human Cholesterol Transport
We develop a two-compartment mathematical model to investigate cholesterol transport in the circulatory system and its de novo synthesis in the liver.
metabolic syndrome
compartment
cholesterol
two-compartment model
cholesterol transport
Potential Scenario
127
views
72
downloads
0
comments
2014-Wrona-EtAl-Two-compartment model as a teaching tool for cholesterol homeostasis
To investigate cholesterol transport in the circulatory system, we have previously developed a two-compartment mathematical model. Here, we show how this model can be used as a teaching tool for cholesterol homeostasis.
metabolic syndrome
compartment model
cholesterol
high blood cholesterol
Potential Scenario
112
views
70
downloads
0
comments
2015-Wrona-EtAl-Two-compartment model as a teaching tool for cholesterol homeostasis
To investigate cholesterol transport in the circulatory system, we have previously developed a two-compartment mathematical model. Here, we show how this model can be used as a teaching tool for cholesterol homeostasis
metabolic syndrome
cholesterol
high blood cholesterol
cholesterol homeostasis
Modeling Scenario
273
views
218
downloads
0
comments
7-010-MultipleDoses-ModelingScenario
Two multiple dose drug administration regimens are offered. A drug is to maintain a certain level (above a set minimum and below a set maximum) in the blood stream and one regimen involves bolus injections and another involves steady drip flow...
drug discovery
step function
dose
Dirac
drug administration
inverse Laplace Transform
intraveneous
bolus
steady drip
Potential Scenario
183
views
50
downloads
0
comments
1986-Istvan_Gyori-Connections between compartment systems pipes and integro-differential equations
In this paper we give the mathematical description of models in which the mass transport between compartments requires a given definite time or transit times are distributed according to given probability distribution functions.
physiology
pipeline
compartment
blood
circulation
integro-differential equation
Potential Scenario
162
views
56
downloads
0
comments
1977-Michael_Mackey-Leon_Glass-Oscillation and Chaos in Physiological Control Systems
First-order nonlinear differential-delay equations describing physiological control systems are studied. The equations display a broad diversity of dynamical behavior including limit cycle oscillation.
sensitivity
chaos
parameters
Respiration
delay
blood cells
Potential Scenario
105
views
46
downloads
0
comments
2007-Exben_Friis-Jensen-Modeling and Simulation of Glucose-Insulin Metabolism
In this thesis one of the models of diabetes, Bergman’s minimal model is described trough derivation and simulations.
Metabolism
insulin resistance
glucose
PID controller
intolerance
Potential Scenario
115
views
47
downloads
0
comments
2019-Radulescu-Lundgren-A_pharmacokinetic_model_of_lead_absorption_and_calcium_competitive_dynamics
We build and analyze a compartmental model of lead pharmacokinetics, focused specifically on addressing neurotoxicity.
QUBES Leadership Team
parameters
absorption
bifurcation
pharmacokinetics
calcium
cognitive decline
Modeling Scenario
261
views
156
downloads
0
comments
1-085-DrugBolus-ModelingScenario
Given data on the concentration of a drug in the plasma of a human in mg/L at certain time intervals in hours can we determine the rate at which the drug leaves the plasma as well as the initial amount administered in a intravenous bolus of the drug?
concentration
sum of square errors
bolus
drug
rate constant
administer
Modeling Scenario
230
views
275
downloads
0
comments
1-160-HeartDeathRate-ModelingScenario
Students simulate experience from a given data set which represents the heart death rate during the period 2000 - 2010 using several approaches to include exponential decay, difference equation, differential equation, and parameter estimation...
data
heart death rate
Potential Scenario
173
views
53
downloads
0
comments
2015-Valerie_Billard-Pharmacokinetic-pharmacodynamic relationship of anesthetic drugs - from modeling to clinical use
The purpose of this short review is to describe the basis of pharmacokinetics and modeling, the concentration-effects relationship, and drug interactions modeling to offer to anesthesiologists and non-anesthesiologists an overview of the rules to...
anesthesia
pharmacokinetics
pharmacodynamic
anesthetic
Potential Scenario
649
views
39
downloads
0
comments
2000-Erdman-Morelock-A Study of Kinetics The Estimation and Simulation of Systems of First-Order Differential Equations
This paper introduces new and old features of the SAS System for the estimation and simulation of systems of first-order differential equations with emphasis on examples in kinetics.
kinetics
SAS
compartment
pharmacokinetics
Modeling Scenario
583
views
339
downloads
0
comments
5-011-ModelingIbuprofren-ModelingScenario
We consider modeling of data from a clinical experiment administered as oral doses of 400 mg ibuprofen, an analgesic pain reliever. Concentrations of ibuprofen in the serum/plasma of the subjects were recorded after the initial ingestion of the...
data
AIC
Akaike Information Criterion
absorption
sum of square errors
compartment model
ibuprofen
delay
Potential Scenario
151
views
49
downloads
0
comments
2003-Richard-Carson-Tracer kinetic modeling in PET
The use of radiopharmaceuticals and the imaging of their biodistribution and kinetics with modern instrumentation are key components to successful developments in PET.
Metabolism
tomography
radiopharmaceuticals
positron emission
Potential Scenario
137
views
40
downloads
0
comments
1971-Boyes-Scott-Jebson-Godman-Julian-Lidocaine in Man
Plasma levels of lidocaine were measured in 5 normal male volunteers following both intravenous and oral administration of the drug.
p
Pharmacology
pharmacokinetics
lidocaine
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