Support

Support Options

  • Knowledge Base

    Find information on common questions and issues.

  • Support Messages

    Check on the status of your correspondences with members of the QUBES team.

Contact Us

About you
About the problem

Natural Selection in Humans

By HHMI BioInteractive

This film explores the evolutionary connection between an infectious disease, malaria, and a genetic condition, sickle cell anemia.

Listed in Teaching Materials | resource by group HHMI BioInteractive

Download Bundle (194 KB)

We're sorry! Resource content is currently unavailable.

Version 1.0 - published on 01 Jul 2019 doi:10.25334/FY71-6S86 - cite this Last public release: 2.0

Licensed under CC Attribution-NonCommercial-NoDerivatives 4.0 International according to these terms

blood-cells.jpg

Description

Tony Allison first noticed a connection between malaria and the sickle cell trait while working in East Africa in the 1950s. The story of his discovery stands as one of the best understood examples of natural selection in humans in which the selective agent, adaptive mutation, and molecule involved are all known. The protection against malaria provided by the sickle cell mutation demonstrates how evolution does not necessarily result in optimal solutions for the species but proceeds in response to selective pressures by utilizing what variation is available.

The “Abbreviated Film Guide” provides a short summary of the film, along with key concepts and connections to curriculum standards.

Contents

Cite this work

Researchers should cite this work as follows:

Tags

HHMI BioInteractive

HHMI BioInteractive group image

When watching a resource, you will be notified when a new version is released.