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Bioinformatics: CpG Islands

Author(s): Edward Himelblau

California Polytechnic State University

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This is an introductory bioinformatics exercise intended for use in a genetics course.

Licensed under CC Attribution-ShareAlike 4.0 International according to these terms

Version 1.0 - published on 17 Oct 2017 doi:10.25334/Q4QD5W - cite this


This is a small-scale, introductory activity for a genetics course (50 students) that students could complete independently outside of class. Students chose a eukaryotic organism and download all 5kb upstream sequences from the UCSC database. Students use free on-line CpG island search tools to analyze a set of sequences. Student have to use their ingenuity to design a figure that displays the frequency and location of CpG islands...some of these figures are used later in lecture as illustrations when epigenetics is covered.

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