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Module 6: Alternative Splicing

Author(s): Leocadia Paliulis1, Anne Rosenwald2

1. Bucknell University 2. Georgetown University

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This module explores how multiple different mRNAs and polypeptides can be encoded by the same gene. After completing this module students will be able to explain how alternative splicing of a gene can lead to different mRNAs.

Licensed under CC Attribution-ShareAlike 4.0 International according to these terms

Version 1.0 - published on 25 Jul 2020 doi:10.25334/B3AH-GV62 - cite this


Many genes have exons that can be linked together in more than one way to produce a variety of different (though related) transcripts. In this lesson, students will examine how alternative splicing of a gene can lead to different mRNAs and how alternative splicing can lead to the production of different polypeptides and result in drastic changes in phenotype.

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