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Module 6: Alternative Splicing

By Leocadia Paliulis1, Anne Rosenwald2

1. Bucknell University 2. Georgetown University

This module explores how multiple different mRNAs and polypeptides can be encoded by the same gene. After completing this module students will be able to explain how alternative splicing of a gene can lead to different mRNAs.

Listed in Teaching Materials | resource by group Genomics Education Alliance

Version 1.0 - published on 25 Jul 2020 doi:10.25334/B3AH-GV62 - cite this

Licensed under CC Attribution-ShareAlike 4.0 International according to these terms

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Description

Many genes have exons that can be linked together in more than one way to produce a variety of different (though related) transcripts. In this lesson, students will examine how alternative splicing of a gene can lead to different mRNAs and how alternative splicing can lead to the production of different polypeptides and result in drastic changes in phenotype.

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