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Luria-Delbruck

Author(s): Tony Weisstein1, John R Jungck2, Doug Green3

1. Truman State University 2. Interdisciplinary Science Learning Center at the University of Delaware 3. Saint Michael's College

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Summary:
These two workbooks model the evolution of phage resistance in a bacterial population under two alternative hypotheses.

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Version 1.0 - published on 11 Sep 2018 doi:10.25334/Q40H75 - cite this

Description

These two workbooks model the evolution of phage resistance in a bacterial population under two alternative hypotheses. Under the hypothesis of acquired immunity, mutation produces some resistant bacteria even in the absence of phage; this resistance can be passed to their offspring. Under the mutation hypothesis, by contrast, mutation produces some resistant bacteria even in the absence of phage; again, this resistance can be passed to their offspring. Predictions of the two models can be compared to each other and to actual data.

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