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Genome Solver: Complete Set of Lessons

Author(s): Anne Rosenwald1, Gaurav Arora2, Vinayak Mathur3

1. Georgetown University 2. Gallaudet University 3. Cabrini University

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The Genome Solver Project began as a way to teach faculty some basic skills in bioinformatics - no coding or scripting. These Lessons also work well in the undergraduate classroom, culminating with an authentic community research project.

Licensed under CC Attribution-ShareAlike 4.0 International according to these terms

Version 2.0 - published on 23 Oct 2019 doi:10.25334/E4GQ-2S85 - cite this


There are 6 Lessons in the Genome Solver Project

  • Lesson I - Introduction
  • Lesson II - Databases
  • Lesson III - Annotation 
  • Lesson IV - Comparative Genomics 
  • Lesson V - Phylogenetics 
  • Lesson VI - The Community Science Project on Horizontal Gene Transfer 
  • Lesson VII - Synteny 

Each lesson contains a slide deck and transcript.  Lessons II - V also have exercises to practice the tools introduced in that slide deck.  Each of the first five lessons takes an hour or less of class time, lecture and exercise.  By working through the first 5 lessons, participants will have the skills necessary to participate in the Community Science Project, an effort to understand the extent to which exchanges of genetic material from bacteriophages and bacteria drives bacterial diversity and evolution.  


Materials were updated as of Fall 2018.  Note that because the slide decks and exercises point to external websites and web-based tools, some of the illustrations contained in the materials may not look exactly like the live website.  Functionality is usually unchanged. 

Fall 2019 - Added a new Lesson on Synteny. 

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