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Finding Selection in All the Right Places

Author(s): Juliet F. K. Noor, Mohamed A. F. Noor

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Description

This inquiry-based laboratory introduces students to evolutionary genetics using bioinformatics and biocuration. The exercise focuses on manual curation and analysis of genome sequences from closely related species. Students assess computationally-generated alignments and annotations of multiple genes from population genomic data sets; repair alignment errors; apply population genetic tests for natural selection; and finally, interpret the results and hypothesize about the nature of selective forces in the context of function information available for the genes.

Citation:

Noor, J. K. F. and Noor, M. A. F. (2013). Finding Selection in All the Right Places: A College Genetics Laboratory Inquiry-Based Learning Exercise. Genetics Society of America Peer-Reviewed Education Portal (GSA PREP): 2013.001; doi: 10.1534/gsaprep.2013.001

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