QUBES - Resources

Investigating Enzyme Structure and Function Through Model-Building and Peer Teaching in an Introductory Biology Course

A foundational knowledge of the relationship between structure and function is critical to understanding how enzymes work. The seemingly invisible nature of these molecular interactions makes it...

Keywords: structure-functionEnzymeallosteric regulationcompetitive inhibitionfeedback inhibitionnoncompetitive inhibitionproductsubstrate

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Unwrapping Enzyme Kinetics

Enzyme rates and kinetics are key components used by biochemists to understand how enzymes function. However, students often find it difficult to understand how these experiments are performed and...

Keywords: kineticsstructure-functionenzymescatalysis

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Glycolysis Can Be Fun: Rediscovering Glycolysis as a Problem-Solving Introduction to Metabolism

A thorough understanding of glycolysis forms a foundation for students to analyze subsequent topics in metabolism, a core competency recognized by multiple national societies for biology and...

Keywords: Problem based learningPOGILenzymesGlycolysisMetabolismFermentationchemical reactionsCard sorting activityCofactors

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Breaking It Down: What Factors Control Microbial Decomposition Rates?

Demonstrating and modeling changes in ecosystem processes in the laboratory classroom can be logistically difficult and expensive. This complexity often leaves little time for students to generate...

Keywords: data analysishypothesis testingdata visualizationdata managementMicrobial RespirationDecompostionAbiotic ConditionsResults Communication

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Bringing Pasteur Back to Life: Studying the Biochemistry of Yeast Fermentation Through Discussion Groups and an At-Home Lab

This hands-on, student-centered biochemistry lesson introduces beginner biochemistry students to the techniques of effectively reading and discussing primary literature, identifying fundamental...

Keywords: primary literatureexperimentationyeastMetabolismFermentationRespirationequilibrium

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The Avocado Lab: An Inquiry-Driven Exploration of an Enzymatic Browning Reaction

Typical biochemistry labs exploring basic enzyme activity rely on costly, time-consuming protein purification and rarely explore enzyme function in situ. Further, complex purification procedures...

Keywords: enzymescontrolsenzyme inhibition

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A 360˚ View of COVID-19

In March 2020, institutions underwent a massive transition to distance learning as a result of the COVID-19 pandemic. With so little time to devise new materials to maximize learning in the new...

Keywords: geneticsImmunologyBiochemistrybioinformaticsmolecular evolutionpublic healthvirusCOVID19

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X-ploring Fragile X: The Science Behind the Syndrome

Fragile X Syndrome is an X-linked genetic disorder resulting from the impairment of transcription of the FMR1 gene, producing less to no FMRP protein. FMRP is a translational inhibitor that plays a...

Keywords: epigeneticsgene regulationtranscriptioncentral dogmatranslationFragile X syndromeSphingosine Metabolism

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Ain't No Mountain Pine Enough: A Case Study of How Mountain Pine Beetles are Affecting Ecosystem Processes

This case study engages students in generating hypotheses and predictions, analyzing and interpreting data, critically evaluating contrasting results in science, and thinking about feedbacks...

Keywords: population biologycarbon cyclingSpecies-habitat interactions

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Using Bioinformatics and Molecular Visualization to Develop Student Hypotheses in a Malate Dehydrogenase Oriented CURE

Developing student creativity and ability to develop a testable hypothesis represents a significant challenge in most laboratory courses. This lesson demonstrates how students use facets of...

Keywords: bioinformaticsNoncovalent InteractionsEnzyme CatalysisProtein Structure/function

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Snail Races: An Inquiry-Based Approach to Learn Invasive Species Ecology

Inquiry-based lessons allow learning that is hands-on and student-driven, fostering engagement and retention of knowledge in any discipline. Here, we use this learning framework to engage students...

Keywords: ecologyenvironmentInvasive SpeciesScience CommunicationScientific InquiryDispersal

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A new approach to course-based research using a hermit crab-hydrozoan symbiosis

There are few feasible models for marine-focused inquiry laboratory activities, a notable shortcoming for instructors seeking to engage their students in meaningful, course-based research...

Keywords: behaviorparasitismSymbiosismutualismcommensalism

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Fostering Student to Student Collaboration Across Institutions in a Protein Centric CURE

Collaboration is an essential component of research because it allows scientists to share expertise and tackle difficult scientific questions. While many undergraduate science courses include...

Keywords: communicationBiochemistrycollaborationCUREhypothesisStudent to StudentInter institutionalProtein CentricAssignments

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Designing an Asynchronous, Self-Led Aquatic Ecology Field Trip

Due to the COVID-19 pandemic and increasing need to teach students online, aquatic scientists are looking for ways to give students field experiences virtually. Asynchronous, self-led field trips...

Keywords: observationecosystem structureexploration

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Gotcha! Which fly trap is the best? An introduction to experimental data collection and analysis

Collecting data from experimental observations is an important component of the scientific process; likewise, the analysis of the data is essential to understanding the observed trends and patterns...

Keywords: data analysisexperimental designdata collectionfruit fliesfly traps

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Predicting and classifying effects of insertion and deletion mutations on protein coding regions

Mutations in genes can affect the encoded proteins in multiple ways, and some of these effects are counterintuitive. As for any other knowledge, students must create their own deep understanding of...

Keywords: mutationcentral dogmatranslationframeshift

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Dynamic Daphnia: An inquiry-based research experience in ecology that teaches the scientific process to first-year biologists

This authentic research experience lesson teaches the core concept of systems and the competencies of quantitative reasoning, communication, and the ability to apply science. The research is...

Keywords: statisticsecologyscientific methodexperimental designAbiotic and Biotic FactorsDependent and Independent Variables

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Investigating Enzyme Structure and Function Through Model-Building and Peer Teaching in an Introductory Biology Course

Unwrapping Enzyme Kinetics

Glycolysis Can Be Fun: Rediscovering Glycolysis as a Problem-Solving Introduction to Metabolism

Breaking It Down: What Factors Control Microbial Decomposition Rates?

Bringing Pasteur Back to Life: Studying the Biochemistry of Yeast Fermentation Through Discussion Groups and an At-Home Lab

The Avocado Lab: An Inquiry-Driven Exploration of an Enzymatic Browning Reaction

A 360˚ View of COVID-19

X-ploring Fragile X: The Science Behind the Syndrome

Ain't No Mountain Pine Enough: A Case Study of How Mountain Pine Beetles are Affecting Ecosystem Processes

Using Bioinformatics and Molecular Visualization to Develop Student Hypotheses in a Malate Dehydrogenase Oriented CURE

Snail Races: An Inquiry-Based Approach to Learn Invasive Species Ecology

A new approach to course-based research using a hermit crab-hydrozoan symbiosis

Fostering Student to Student Collaboration Across Institutions in a Protein Centric CURE

Designing an Asynchronous, Self-Led Aquatic Ecology Field Trip

Gotcha! Which fly trap is the best? An introduction to experimental data collection and analysis

Predicting and classifying effects of insertion and deletion mutations on protein coding regions

Dynamic Daphnia: An inquiry-based research experience in ecology that teaches the scientific process to first-year biologists

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