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    Does Organelle Shape Matter?: Exploring Patterns in Cell Shape and Structure with High-Throughput (HT) Imaging
    Organelle structure has been studied and visualized for decades; however, publicly available databases that use improved high-throughput microscopy of gene-edited cell lines have recently...

    Keywords: modelingcase studymicroscopystructureOrganellesHigh-throughput (HT)Endoplasmic Reticulum (ER)Fluorescent microscopyHuman Cell Biology

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    A Hands-on Introduction to Hidden Markov Models
    In this Lesson, we describe a classroom activity that demonstrates how a Hidden Markov Model (HMM) is applied to predict a eukaryotic gene, focusing on predicting one exon-intron boundary. This HMM...

    Keywords: transcriptionexonintronsplicing

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    Instructor Guide: Integrating Project Leadership, Artificial Intelligence, Simulation and Google Tools to Understand Regulation of Gene Expression with the Lac Operon and Lactase Gene
    Scientific leadership and current artificial intelligence (AI) skills are important skills to be included in the course curriculum. Together or individually, these skills can enhance knowledge,...

    Keywords: Resources @ HHMI - BioInteractivebiologymolecular biologygenomicsArtificial Intelligencegene expressionleadershipgroup worklactosegoogle toolsSeniorPhET SimulationLactase

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    2006-Juska-Gedminiene-Ivanec-Growth of Microbial Populations-Mathematical Modeling-Laboratory Exercises-Model-Based Data Analysis
    The aim is to teach the students to use a fresh approach to the problems they are familiar with, to come up with an articulate verbal model after a mental effort, to express it in rigorous...

    Keywords: population growth ratelogistic equationVerhulst equationgeneration timelag time

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    2018-Robert_Phair-Differential_equation_methods_for_simulation_of_GFP_kinetics_in_non–steady_state_experiments
    Here, we derive new tracer kinetic analytical methods for non–steady state biological systems by constructing mechanistic nonlinear differential equation models of the underlying cell biological...

    Keywords: protein quality controlkineticsCellssteady statechemical kineticsfluouresencephotoactivationinytracellular

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    Hypoxia in Coastal Marine Ecosystems (Project Eddie) - Modified
    Aquatic ecosystems are home to a complex intersection of physical and biological factors and an intersection of natural and anthropogenic factors. In the Chesapeake Bay, low oxygen events have...

    Keywords: OceanographyProject EDDIEEutrophication

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    Hypoxia in Coastal Marine Ecosystems (Project Eddie)
    Aquatic ecosystems are home to a complex intersection of physical and biological factors and an intersection of natural and anthropogenic factors. In the Chesapeake Bay, low oxygen events have...

    Keywords: OceanographyProject EDDIEEutrophication

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    Undergraduates Learn Evolution Through Teaching Kindergartners About Blind Mexican Cavefish
    The development and implementation of a scientific outreach activity comes with a number of challenges. A successful outreach event must match the sophistication of content to the audience, be...

    Keywords: Evolutionecologymorphologysensory biologycave biologycomparative biologyenvironmental differencesregressive lossstructure and function

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    Biodiversity Counts! Making sense of diversity metrics and graphs
    In this lesson students 1) become familiar with various graphs that are used to study diversity patterns within and across sites, 2) learn about some of the questions that can be addressed by...

    Keywords: graph interpretationfmnmetabarcodingbiodiversity literacyBioGraphIrepresentation in STEMalpha diversitybeta diversity

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    What’s the DEAL – The Digital Encyclopedia of Ancient Life and Digital Atlas Apps
    The Digital Encyclopedia of Ancient Life and Digital Atlas Apps -- identify fossils and explore diversity and history of life on earth.

    Keywords: phylogeneticsdigital resourcesfossilspaleontologyevolutionary biologytaxonomyeduappsnatural history collections3D modelsgeologyopen textbookdigitized natural history collectionsencyclopediaatlasCretaceous World TCNPaleo Niches TCNvirtual teaching collectionFossil field guide

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    Data on Dead Zones and a Scientist Spotlight Featuring Benjamin Negrete, Jr.
    In this lesson, students plot data and interpret graphs of the metabolic responses of fish to hypoxic conditions. Then, students view and reflect on an interview with fish ecophysiologist Benjamin...

    Keywords: fishgraphinggraph interpretationhuman-environmental interactionsdata literacysocial justicemarineCODAP

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    Hardy-Weinberg Equilibrium: a swirl resource
    Students will use swirl to understand Hardy-Weinberg equilibrium. The lesson starts with observed numbers of individuals for each genotype, and students will work through a number of steps to...

    Keywords: Hardy-Weinbergpopulation geneticsEvolutionevolutionary ecologyR programming languageSwirl

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    Sickle Cell Disease Case Study
    A short film explores the evolutionary connection between an infectious disease, malaria, and a genetic condition, sickle cell anemia. The animation explores the genetic causes and biological...

    Keywords: HHMI BioInteractive

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    Using Data Science Skills and Digitized Natural History Collections Data to Investigate Ecological and Evolutionary Principles in Introductory Biology Courses
    Session presentation Biodiversity Literacy in Undergraduate Education project at the 2019 BioQUEST & QUBES Summer Workshop

    Keywords: data sciencenatural history collections2019 QUBES/BioQUEST Summer WorkshopBLUEdigitized natural history collections

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    How Many More Thymes & Herbivore Defense
    Adaptations to the How Many More Thymes? case study featuring terpene-based herbivore defense and pollinator attraction in Nicotiana plants.

    Keywords: food websgenotypephenotypeHerbivoryherbivoredeterrencemonoterpeneproducerchemotypeThymus vulgaristhymeMediterranean ecosystemchemical defensesManduca sextaNicotiana

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    The Insect Predation Game: Evolving Prey Defenses and Predator Responses
    Laboratory experiment included in Teaching Issues and Experiments in Ecology (TIEE) Volume 4

    Keywords: simulationpredator-preypredation ecology

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    The Insect Predation Game: Evolving Prey Defenses and Predator Responses
    Laboratory experiment included in Teaching Issues and Experiments in Ecology (TIEE) Volume 4

    Keywords: simulationpredator-preypredation ecology

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    The Insect Predation Game: Evolving Prey Defenses and Predator Responses
    Laboratory experiment included in Teaching Issues and Experiments in Ecology (TIEE) Volume 4

    Keywords: simulationpredator-preypredation ecology

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    A Walk Through the Woods
    Data driven curriculum module from Dryad Digital Repository

    Keywords: ecologygraphingResources @ Dryadhypothesis testingdata visualizationbotanyclimate changeadaptationforestryDryadLabhypothesis formulationenvironmental pressureswood structure and function

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    5-024-PhGreatLakes
    In this teaching modeling scenario, we demonstrate how lessons on salt-tank compartmental modeling can be used to predict phosphorus levels in the Great Lakes.

    Keywords: Great Lakeslimnologycomparmentpollutioncompartmental modelsphosphorous

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