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    X-ploring Fragile X: The Science Behind the Syndrome
    Fragile X Syndrome is an X-linked genetic disorder resulting from the impairment of transcription of the FMR1 gene, producing less to no FMRP protein. FMRP is a translational inhibitor that plays a...

    Keywords: epigeneticsgene regulationtranscriptioncentral dogmatranslationFragile X syndromeSphingosine Metabolism

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    Adapting a Traditional Laboratory Exercise to Become Inquiry Based: An Example With an Introductory Biology Lab in Diffusion
    Authentic research experiences are effective in fostering self-efficacy and increasing retention in STEM, particularly among minoritized student populations. Many instructors have sought to bring...

    Keywords: protocolquestionDiffusionVariableshypothesisscience processcontrolscientific efficacy

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    Space Mission Ecology: Making Connections Among Science Disciplines Through the Lens of a Unique Plant
    With this case study, we aim to increase awareness of essential services plants provide to society, as well as the importance of fundamental aspects of ecology for other disciplines and the...

    Keywords: ecologycollaborationplant biologyScience CommunicationBioregenerative Life SupportInterdisciplinary Connections

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    Environmental Injustice: When the Grass is Greener on the Other Side
    Environmental pollution is a global threat that is especially prevalent in heavily industrialized and urbanized areas. Pollution can be found in many forms, such as natural and synthetic pollutants...

    Keywords: human healthenvironmental injusticeEnvironmental PollutionSystemic BiasesIdeological AwarenessUrban Ecology and Development

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    Kinetics of a Highly Conserved Enzyme - Carbonic Anhydrase
    This module contains exercises designed to introduce students to graphical representation of biological data. Students will explore the fundamental principles of enzyme kinetics including...

    Keywords: Excelintroductory biologycell biologygraphingslopeQuantitative reasoningdata visualizationquantitative biologyinterdisciplaryquantitative skillscorrelationenzyme functionInterpreting GraphsMichaelis-Mentenenzyme kineticsEnzyme activityenzyme inhibitionLinear and nonlinear analysisNIQBC2. Data and GraphsC4. mathematical modelsenzyme-substrateNIQB Interdisciplinary Quantitative Reasoningcarbonic anhydrase

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    The Science and Ethics of Gene Drives: An Active Learning Lesson in Genetics
    Coursework connecting biology to socially relevant issues and ethical questions can help students think about biology in interdisciplinary terms. Gene drives represent one topic involving both...

    Keywords: bioethicsCRISPR/Cas9Genetic modificationGene drives

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    A Journal Club Project to Promote Interpreting and Presenting Information From the Primary Scientific Literature
    Many undergraduate students receive little guidance on how to critically read, interpret data within, or present information from the primary scientific literature before they begin senior...

    Keywords: primary literaturejournal clubScience CommunicationfeedbackPeer reviewgroup workOral presentationProcess skillsPeer evaluationDevelopmental neurobiology

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    Glycolysis Can Be Fun: Rediscovering Glycolysis as a Problem-Solving Introduction to Metabolism
    A thorough understanding of glycolysis forms a foundation for students to analyze subsequent topics in metabolism, a core competency recognized by multiple national societies for biology and...

    Keywords: Problem based learningPOGILenzymesGlycolysisMetabolismFermentationchemical reactionsCard sorting activityCofactors

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    Serial Dilutions
    In this Excel workbook, users will enter the original cell concentration and the desired dilution factor (10, 100, and 1000). The program will then calculate the new cell concentration.

    Keywords: concentrationScientific Notationorders of magnitudeserial dilutions

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    Mark-Recapture
    A common method used to estimate the population size of a species is the Mark-Recapture method.

    Keywords: mark-recapture analysispopulation estimation

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    Evolution Through Natural Selection
    This Excel workbook simulates the population genetics of a single gene with two alleles, allowing the user to set the initial allele frequencies and enter parameters for a variety of different...

    Keywords: population geneticsNatural Selection

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    Dynamic Programming
    In bioinformatics, dynamic programming is mainly used to align nucleotide and amino acid sequences, and to predict RNA and protein folding from primary sequence data.

    Keywords: RNAamino acid sequenceSequence alignmentdynamic programmingprotein folding

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    Deme 2.0
    This workbook simulates the population genetics of a single gene with two alleles. It can simultaneously model up to three local populations, which may differ in their selection coefficients.

    Keywords: population geneticsGenetic DriftNatural Selection

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    DeFinetti 1.0
    This Excel workbook simulates evolution of a single gene with three alleles. The user assigns fitness values to each of the six possible genotypes, then enters starting allele frequencies for each...

    Keywords: population geneticsallelesevolutionary fitness

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    Defining Life: Exploring Creativity, Scientific Discovery, and Biology Core Concepts in a Disciplinary First-Year Seminar
    This unit, Defining Life, engages students in thinking like scientists, applying creativity to science, and learning biology core concepts as they explore the defining characteristics of life. This...

    Keywords: Evolutionbiologycellprocess of science

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    Cell Cycle and Mitosis
    This module introduces activities that allow students to walk through the cell cycle and mitotic cell division processes. As part of the activities, students learn about and apply knowledge of...

    Keywords: introductory biologyQuantitative reasoningInterdisciplinary STEMquantitative biologyinterdisciplinaryquantitative skillscell functioncell cyclemitosisCell DivisionMitotic Indexcalculating meanstumorNIQBC2. Data and GraphsC4. mathematical modelsC3. Statistical Analysisstandard errormitotic phaseinterphase

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    Long-read Sequencing Technology
    This 50 minute lecture on long-read sequencing technology covers the following items: 1) Review of RNA-Seq Short-read Sequencing, 2) Overview and benefits of Long-read Sequencing, 3) Oxford...

    Keywords: sequencingDNA sequenceRNA sequencingNanoporepacbiopacific biosciences

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    Cancer Genetics and an Interview with a Deaf Biomedical Researcher
    In this lesson, learners will learn about cancer genetics and understand and interpret graphs showing quantitative trait locus (QTL) data, survivor curve data, and other genetics data. Then,...

    Keywords: graph interpretationfmnDeaf EducationBioGraphIrepresentation in STEMBioGraphI graph InterpretationDeaf representation in STEM

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    Let me in: Interpreting graphs of parasite infection in red blood cells
    The goal of this activity is to familiarize students with reading graphs, to think about how cells are different from one another and how parasites can take advantage of cell surface markers to...

    Keywords: graph interpretationfmnCellsStem cellsmalariaBioGraphIrepresentation in STEMcell sortinginfection efficiencycell surface proteinscell recongitionred blood cells

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    A Structured Inquiry-Based Module for the Undergraduate Cell Biology Laboratory That Teaches Fundamental Concepts of Cell Differentiation
    Pedagogical research in science education has shown that students effectively learn science by doing science. As a result, there is increased interest in bringing research-like experiences into the...

    Keywords: fluorescence microscopygene expressionpolymerase chain reactionCell Structurecell culturewestern blottingdifferentiationreverse transcription

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