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    Pick Your Poison: A Semester-Long Case Study for Undergraduate Toxicology
    The ability to collate information from diverse scientific resources and effectively employ scientific writing is an essential skill for scientists. This lesson describes a semester-long project...

    Keywords: risk assessmenttoxicologyPharmacologyregulationsdose responseADME

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    Using Yeast to Make Scientists: A Six-Week Student-Driven Research Project for the Cell Biology Laboratory
    Traditionally-trained undergraduate students often lack an understanding of science as an active process that yields the information presented in their textbooks. One result has been a call for...

    Keywords: yeastgrowth curvecell proliferationviability

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    Using Open-Source Bioinformatics and Visualization Tools to Explore the Structure and Function of SARS-CoV-2 Spike Protein
    The relationship between protein structure and function is a foundational concept in undergraduate biochemistry. We find this theme is best presented with assignments that encourage exploration and...

    Keywords: bioinformaticsmolecular modelingCOVID19protein structure and functionUCSF ChimeraSARS-CoV-2 spike proteinACE2 receptor

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    Pesticides in My Smoothie Bowl?
    Teaching resources, especially active learning pedagogy, are scarce for toxicology compared to what is available for other disciplines. Ecological and human health risk assessment are...

    Keywords: data analysistoxicologychemical toxicityecological risk assessmenthuman risk assessmentpesticide

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    Glycolysis Can Be Fun: Rediscovering Glycolysis as a Problem-Solving Introduction to Metabolism
    A thorough understanding of glycolysis forms a foundation for students to analyze subsequent topics in metabolism, a core competency recognized by multiple national societies for biology and...

    Keywords: Problem based learningPOGILenzymesGlycolysisMetabolismFermentationchemical reactionsCard sorting activityCofactors

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    5-007-ChemOpt-ModelingScenario
    Modeling a chemical reaction and estimating parameters in the model permits optimization of profits from extracting reactants.

    Keywords: optimizationpYield and sustainabilitynonprofit managementLaw of Mass Actionkineticreaction

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    2007-Ramsay-Hooker-Campbell-Cao-Parameter estimation for differential equations-a generalized smoothing approach
    We propose a new method for estimating parameters in models that are defined by a system of non-linear differential equations.

    Keywords: estimating equationfunctional data analysisGauss–Newton methodparameter cascadeprofiled estimationdynamic system

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    1967-Israelsson- Johnsson-Circumnutations In Helianthus Annuus
    A theory is given for circumnutations in plants, especially hypocotyls of Helianthus annuus, which were used as experimental material.

    Keywords: plantoscillationdelaycircumnutationturning

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    2018-Robert_Phair-Differential_equation_methods_for_simulation_of_GFP_kinetics_in_non–steady_state_experiments
    Here, we derive new tracer kinetic analytical methods for non–steady state biological systems by constructing mechanistic nonlinear differential equation models of the underlying cell biological...

    Keywords: protein quality controlkineticsCellssteady statechemical kineticsfluouresencephotoactivationinytracellular

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    Happy Blue Baby
    This case, about a specific mutant of hemoglobin, focuses on visualizing and understanding the molecular basis of why an infant turned blue soon after birth and how the cyanosis resolved on its own...

    Keywords: mutationHemoglobinmolecular visualization and analysisgenetic basisPDBMolecular Case StudyMol*

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    Waking up Anna - Adaptations and Conversion to Mol*
    This case focuses on understanding the molecular basis of Anna's sleeping disorder and its treatment. The adaptations addressed question clarity and reformatting to use Mol*.

    Keywords: sleepmolecular visualization and analysisPDBMolecular Case StudyGABAMolCaseNetMol*MolStarProtein visualizationFlumazenil

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    The Happy Blue Baby Hemoglobin
    This case, about a specific mutant of hemoglobin, focuses on visualizing and understanding the molecular basis of why an infant turned blue soon after birth and how the cyanosis resolved.

    Keywords: mutationHemoglobinmolecular visualization and analysisPDBMolecular Case Study

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    Waking up Anna
    This case focuses on understanding the molecular basis of Anna's sleeping disorder and its treatment.

    Keywords: sleepmolecular visualization and analysisPDBMolecular Case StudyGABA

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    The nose knows: How tri-trophic interactions and natural history shape bird foraging behavior. An introduction to statistical analysis in animal behavior research
    Students investigate the role of olfaction and infochemicals on bird foraging behavior through two different quantitative activities where they generate hypotheses, create figures, conduct data...

    Keywords: Resources @ ESA - TIEEforagingfmnanimal behaviorbehavioral ecologyDIGtrophic cascades

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    Causes and consequences of resisting herbivory: How long-lived plants avoid damage from diverse short-lived insect herbivores
    This module guides students through decades-long studies of tropical plant-insect interactions to elucidate the ecology and evolution of plant defenses while encouraging students to consider the...
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    Using a Sequential Interpretation of Data in Envelopes (SIDE) approach to identify a mystery TRP channel
    This lesson sought to engage students in data interpretation and to encourage critical thinking about neurophysiology in the context of temperature sensation. A family of receptors called Transient...

    Keywords: Cell communicationChannel specificity and activationLimitations of tools of Cell BiologyNeuronal Signaling

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    2012-Brian_Ingalls-Mathematical Modelling in Systems Biology An Introduction
    This is a comprehensive text with much biology background to motivate the mathematical modeling, exercises and answers, and many rich examples.

    Keywords: spatialsensitivity analysisgene regulatory networksstochasticbifurcationmetabolic networkselectrophysiologytransductionrate lawsbiochemical reactions

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    Biting into "Science Cookies": Are seed fates determined by seed size or chemistry?
    By understanding how animals make seed dispersal decisions, we can predict how plant traits affect seed survival and plant recruitment. Using wild agoutis, we experimentally tested how seed...

    Keywords: predationplant animal interactionsSymbiosisTrophic interactionsTropical ecosystemsArtificial seedsSeed dispersalTerrestrial mammal

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    2011-Nancy_Rodrıguez-Applied Partial Differential Equations in Crime Modeling and Biological Aggregation
    In the first part we study a fully-parabolic system of PDEs for residential burglary ‘hotspots’ (spatio-temporal areas of high density of crime). In this work we are concerned with the existence...

    Keywords: biologyDiffusionKeller-Segel modelchemotaxiscrime

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    1984-Marguerite_Hays-Compartmental Models for Human Iodine Metabolism
    Compartmental models for the various aspects of human iodine metabolism are reviewed, emphasizing the role of Mones Berman in the development of this field.

    Keywords: compartment modeliodinethyroid

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