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    Osmosis: Determination of the rate of osmosis and the isotonic concentration
    This module contains exercises designed to help students understand how solute concentrations affect the direction and rate of osmosis. Students are given different scenarios to predict the...

    Keywords: introductory biologyQuantitative reasoninginterdisciplinarycell functionOsmosisNIQBC2. Data and GraphsC4. mathematical modelsC6. Quantitative LanguageC1. NumeracyC5. Logic and Algorithms

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    6-005-InsectColonySurvivalOpt-ModelingScenario
    We present a system of nonlinear differential equations to model the control of energy flow into producing workers or reproducers in an insect colony, using a set of given parameters and a number...

    Keywords: optimizationOptimal Control Theoryinsect colonyoptimal controlnatural resourcesPointryagin's Maximum Principlecontrol variable

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    2017-Sim-EtAl-Optimal control of a coupled tanks system with model-reality differences
    In this paper, an efficient computational approach is proposed to optimize and control a coupled tanks system.

    Keywords: optimal controlflowtankscoupled tanks

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    2007-Exben_Friis-Jensen-Modeling and Simulation of Glucose-Insulin Metabolism
    In this thesis one of the models of diabetes, Bergman’s minimal model is described trough derivation and simulations.

    Keywords: Metabolisminsulin resistanceglucosePID controllerintolerance

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    1-035-DotseroVolcanoEruption-ModelingScenario
    In this scenario, we use Carbon-14 dating of the Dotsero volcano in Colorado as a way of emphasizing this multistage process of modeling.

    Keywords: exponential decayhalf-lifedecayEuler's methodcarbon datingdecay rateCarbon-14Dotsero volcanovolcano

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    6-001-Epidemic-ModelingScenario
    This paper presents real-world data, a problem statement, and discussion of a common approach to modeling that data, including student responses. In particular, we provide time-series data on the...

    Keywords: datadifference equationsparameter estimationcontinuousepidemicdiscreteboarding school

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    9-030-WaterHammer-ModelingScenario
    We develop and apply a numerical algorithm that solves a system of two nonlinear partial differential equations (PDEs) that describes the time evolution of the water hammer phenomenon.

    Keywords: Stock and Flow modelhyperbolic equationsfinite differenceswater hammerhydrodynamicscompressibilitywave celerity

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    Integrating Manipulatives and Animations to Visualize Holliday Junctions
    The complex molecular architecture of Holliday junctions is often challenging for undergraduate biochemistry students to conceptualize. In particular, they have difficulty translating from...

    Keywords: dna structureDNA damageDNA recombinationGene crossoverHolliday junction

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    Joel E. Greengiant Learns About Peas: From Nucleotides to Selection
    This case study follows purveyors of peas, Joel E. and Jolene Greengiant, as they learn about the origin, biochemistry, genetics and eventual artificial selection of sweet (wrinkled) peas, all in...

    Keywords: geneticspopulation geneticsEvolutionintroductory biologycase studybiologyResources @ NSF - NCCSTSmeiosisMendel’s peaspea plantPisum sativumMendel’s Lawsmolecular geneticsmutationnucleotide insertionartificial selectionstarch synthesisstarch branching enzymeplant domesticationlegumesResources @ QUBES - Teaching & Reference

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    The Evolution of Color Vision in Monkeys: From Nucleotides to Ecology
    This case study examines the evolution color vision in Old World and New World monkeys from multiple biological perspectives.

    Keywords: phylogeneticsgenescase studybiologyResources @ NSF - NCCSTSColor visiondichromatictrichromaticnucleotidesproteinsopsinscell functioncone cellsphotoreceptorsspectral shiftgene duplicationmeiosissex-linkedfood gatheringmonkeysprimatesResources @ QUBES - Teaching & Referenceundergraduate biology education

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    A Laboratory Module That Explores RNA Interference and Codon Optimization Through Fluorescence Microscopy Using Caenorhabditis elegans
    Scientific research experiences are beneficial to students allowing them to gain laboratory and problem-solving skills, as well as foundational research skills in a team-based setting. We designed...

    Keywords: microscopyC. elegansquantitative analysisinquiry-based learninggene expressionRNA interferenceCodon UsageLaboratory Module

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    1-144-HeatCool-ModelingScenario
    We offer an opportunity to build a mathematical model using Newton's Law of Cooling for a closed plastic baggie of liquid inside a liquid container.

    Keywords: temperatureNewton's Law of Coolingcooling

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    1-104A-T-InfectionRisk-ModelingScenario
    This project is designed to examine differences between the exponential and logistic growth models in biology and how to apply these models in solving epidemic questions and comparing to actual...

    Keywords: regressioninfectionCOVID19carrying capacitylogistic equationexponential model

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    2017-William_Bialek-Boxes and Arrows To Differential Equations
    This material uses pictures to build kinetic models of reactions and then offers analytic solutions.

    Keywords: Michaelis-MentenEnzymesubstrateDNA\kinetis

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    2012-Campbell-EtAl-Parameter estimation in differential equation models with constrained states
    We introduce a method to estimate parameters and states from a differential equation model while enforcing interpretability constraints such as monotone or non‐negative states.

    Keywords: chemical engineeringsmoothing-based relaxation method

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    1999-Leonid_Hanin-Which tank empties first
    Suppose that water towers like those shown in the opening are initially filled with water and have the same volume, height, and cross-sectional outlet area. Which one empties first?

    Keywords: tankTorricelli's Lawspherical tankemptyfrustrum of conecylinder

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    Mitosis and Meiosis Resources
    New stop-motion ‘candymation’ videos of mitosis and meiosis, plus Instructor Guides and problem sets.

    Keywords: meiosislearningmitosisanimationscell division mechanismschromosomes

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    1997-Jeff_Graham-Julia_Barnes-A Laboratory Experience for Students of Differential Equations Using RLC Circuits
    Acknowleging that applied mathematics courses rarely offer any hand-on experiences the authors constructed an RLC circuit from which they collected data and validated the differential equation of...

    Keywords: datacollectionslaboratorycircuitRLC

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    Aquatic Macroinvertebrates and Urbanization: Exploring urbanization’s effect on leaf litter decomposition in six streams of Puerto Rico using R
    Urbanization effects stream ecosystems by introducing pollutants to the streams.. This has detrimental effects on the life of the streams such as the aquatic macroinvertebrates who are in charge of...

    Keywords: aquatic macroinvertebratesStream ecologyurbanizationsurban runoff

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    5-001-LSD-ModelingScenario
    We describe the use of a two compartment model of a linear system of first order linear differential equations to model lysergic acid diethylamide (LSD) in the body. We provide the data from the...

    Keywords: LSDSpanishcompartmentpharmacokineticslysergic acid diethylamide

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