Text Search:
Applied Filters
    Mentoring Undergraduate Research Projects in Mathematical Biology
    Part of the 2015 SMB Minisymposium: Topics in Biomathematics Education
    1471

    views

    218

    downloads

    0

    comments

    0

    adaptations

    2012-Brian_Ingalls-Mathematical_Modelling_in_Systems_Biology
    This text provides an introduction to dynamic mathematical modeling of cellular processes. The emphasis is on using computational tools to investigate models of cellular phenomena.
    139

    views

    47

    downloads

    0

    comments

    0

    adaptations

    2016-Barbarossa-Kuttler-Mathematical Modeling of Bacteria Communication in Continuous Cultures
    This paper presents a simple system of delay differential equations (DDEs) for quorum sensing of Pseudomonas putida with one positive feedback plus one (delayed) negative feedback mechanism.
    128

    views

    58

    downloads

    0

    comments

    0

    adaptations

    2012-Transtrum-Qiu-Optimal experiment selection for parameter estimation in biological differential equation models
    We explore the question to what extent parameters can be efficiently estimated by appropriate experimental selection.
    174

    views

    47

    downloads

    0

    comments

    0

    adaptations

    Regulation of Gene Expression and Adipogenesis by PPAR-γ
    Students learn about transcriptional regulation of PPAR-γ, an important controller of adipose tissue stores and energy metabolism through a drawing/coloring activity of the different components...
    1816

    views

    1077

    downloads

    0

    comments

    1

    adaptations

    Neochromosomes: Creating transcriptional units with yeast Golden Gate assembly
    This resource is a series of protocols using the yeast Golden Gate (yGG) method as developed by Neta Agmon and Leslie Mitchell in Jef Boeke’s lab to assemble a functional yeast gene with...
    1248

    views

    690

    downloads

    0

    comments

    0

    adaptations

    2012-Brian_Ingalls-Mathematical Modelling in Systems Biology An Introduction
    This is a comprehensive text with much biology background to motivate the mathematical modeling, exercises and answers, and many rich examples.
    451

    views

    89

    downloads

    0

    comments

    0

    adaptations

    Instructor Guide: Integrating Project Leadership, Artificial Intelligence, Simulation and Google Tools to Understand Regulation of Gene Expression with the Lac Operon and Lactase Gene
    Scientific leadership and current artificial intelligence (AI) skills are important skills to be included in the course curriculum. Together or individually, these skills can enhance knowledge,...
    119

    views

    36

    downloads

    0

    comments

    0

    adaptations

    Discovering Prokaryotic Gene Regulation by Building and Investigating a Computational Model of the lac Operon
    The ability to construct and reason through a biological system is an important skill to develop in science education. This level of understanding forces students to recognize the interrelatedness...
    2163

    views

    275

    downloads

    1

    comments

    0

    adaptations

    Investigating Gene Expression and Cell Specialization in Axolotl Embryos
    The process of cell specialization is critical to the formation and function of tissues in animals and plants. Although gene expression, including the regulation of transcription, is taught in most...
    1551

    views

    338

    downloads

    0

    comments

    0

    adaptations

    Module 2: Transcription Part I: From DNA Sequence to Transcription Unit
    This module illustrates how a primary transcript (pre-mRNA) is synthesized using a DNA molecule as the template. Students will learn about the importance of the 5' and 3' regions of the gene for...
    1728

    views

    3350

    downloads

    0

    comments

    0

    adaptations

    Discovering Prokaryotic Gene Regulation with Simulations of the trp Operon
    The trp operon exemplifies important biological concepts, including the central dogma of molecular biology, feedback inhibition, and gene regulation. For this reason, regulation of the trp operon...
    4080

    views

    403

    downloads

    0

    comments

    0

    adaptations

    Open science, open data, open source projects for undergraduate research experiences
    Resource from the 2015 BioQUEST Summer Workshop
    1306

    views

    177

    downloads

    0

    comments

    0

    adaptations

    The Science and Ethics of Gene Drives: An Active Learning Lesson in Genetics
    Coursework connecting biology to socially relevant issues and ethical questions can help students think about biology in interdisciplinary terms. Gene drives represent one topic involving both...
    356

    views

    50

    downloads

    0

    comments

    0

    adaptations

    2008-Brewer-EtAl-Fitting ordinary differential equations to short time course data
    In this paper, we present a survey of existing algorithms and describe the main approaches. We also introduce and evaluate a new efficient technique for estimating ODEs linear in parameters...
    108

    views

    49

    downloads

    0

    comments

    0

    adaptations

    How to Find a Gene: Retrieving Information From Gene Databases
    A strong understanding of distinct gene components and the ability to retrieve relevant information from gene databases are necessary to answer a diverse set of biological questions. However, often...
    1655

    views

    395

    downloads

    0

    comments

    0

    adaptations

    Using Raw Sequence Data to Analyze Tumor Suppressor Mutations
    Learning to identify DNA sequence variants from raw sequencing data (electropherograms) is a basic molecular biology skill with applications to basic research and clinical practice. Yet learning to...
    483

    views

    71

    downloads

    0

    comments

    0

    adaptations

    The Great Petunia Carnage of 2017: A Clicker Case Study Using Petunias to Describe the Effect of Genetic Modification on the Biochemistry of Flower Color and Phenotype in Plants
    In this single class period case study, students examine the difference between genotype and phenotype by studying the mechanisms by which commercially available petunias have been bred to have...
    3659

    views

    62

    downloads

    0

    comments

    0

    adaptations

    Make It Stick: Teaching Gene Targeting with Ribbons and Fasteners
    Manipulating gene expression is a commonly used tool to study the effect of a single gene or the hierarchy of gene networks in many different biological disciplines. When working with mice, the...
    1592

    views

    237

    downloads

    0

    comments

    0

    adaptations

    Introduction to Phylogenetic Trees for Comparative Genomic Analysis
    In this activity, students are introduced to phylogenetic trees and networks as tools for analyzing evolutionary relationships.
    1735

    views

    2377

    downloads

    2

    comments

    0

    adaptations