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  1. Digital Laboratory Framework via Canvas for LIFE courses at Colorado State University

    Digital Laboratory Framework via Canvas for LIFE courses at Colorado State University

    2020-07-28 21:43:59 | Teaching Materials | Contributor(s): Tanya Dewey, Craig Marshall, Kim Hoke, Meena Balgopal | doi:10.25334/FK9V-P927

    The Life Lab Revisions team has piloted a Canvas-based approach to building scientific competencies in labs.

  2. Graphing an Epidemic:  West Africa Ebola Epidemic

    Graphing an Epidemic: West Africa Ebola Epidemic

    2020-07-28 19:16:03 | Teaching Materials | Contributor(s): Lois Bartsch | doi:10.25334/YPQ6-ZV05

    In this activity, students will explore how the Ebola virus outbreak occurred in West Africa through graphing prevalence, incidence and mortality data from the three major countries that were affected by the Ebola virus in 2014 - 2016

  3. Build-a-Genome Lab Manual for RFP Synthesis

    Build-a-Genome Lab Manual for RFP Synthesis

    2020-07-28 16:49:29 | Teaching Materials | Contributor(s): Lisa Scheifele | doi:10.25334/AN0R-BS96

    This lab manual describes a multi-week lab project for the design, assembly from oliognucleotides, cloning, and sequencing of the RFP gene. This resource was developed as part of NSF Award #1827204, RCN-UBE: The Build-a-Genome Network.

  4. The ADW: a database of animal natural history that supports complex, authentic student inquiry.

    The ADW: a database of animal natural history that supports complex, authentic student inquiry.

    2020-07-28 16:17:23 | Teaching Materials | Contributor(s): Tanya Dewey | doi:10.25334/8E3K-C191

    Poster on the Animal Diversity Web and Quaardvark presented at the 2020 BIOME Institute: Cultivating Scientific Curiosity

  5. Anti-bias Education Puppet Plays

    Anti-bias Education Puppet Plays

    2020-07-28 14:56:06 | Teaching Materials | Contributor(s): Julia Robinson | doi:10.25334/E3QW-KM91

    Nature provides science content for teacher preparation certification programs and the backdrop for puppet plays used as a springboard for teaching the NAEYC's four goals of Anti-bias Education-Identity, Diversity, Justice and Activism.

  6. Yeast Scramble Lab Manual

    Yeast Scramble Lab Manual

    2020-07-28 13:48:43 | Teaching Materials | Contributor(s): Mark Jones, Lisa Scheifele | doi:10.25334/9N64-QR80

    This laboratory manual includes protocols for SCRaMbling of yeast cells as well as phenotypic characterization. Appropriate student exercises are also included. This resource was developed as part of NSF Award #1827204, RCN-UBE: The Build-a-Genome Network

  7. Engaging students in data exploration using digital biodiversity databases: BLUE Data Network

    Engaging students in data exploration using digital biodiversity databases: BLUE Data Network

    2020-07-27 21:04:48 | Teaching Materials | Contributor(s): Anna Monfils, Debra Linton | doi:10.25334/4K4E-B455

    Slides for BLUE presentation at 2020 BIOME Institute: Cultivating Scientific Curiosity

  8. Integrating digitized biodiversity data exploration into the undergraduate biology curriculum

    Integrating digitized biodiversity data exploration into the undergraduate biology curriculum

    2020-07-27 17:05:26 | Teaching Materials | Contributor(s): Debra Linton, Libby Ellwood, Lisa White, Anna Monfils | doi:10.25334/E4PN-GZ50

    Poster on the Biodiversity Literacy in Undergraduate Education (BLUE) project presented at the 2020 BIOME Institute: Cultivating Scientific Curiosity

  9. CyVerse: Scalable Image Informatics

    CyVerse: Scalable Image Informatics

    2020-07-27 15:41:03 | Teaching Materials | Contributor(s): Tyson Lee Swetnam, Edwin Skidmore, Tony Edgin, Ramona Walls, Eric Lyons, Nirav Merchant | doi:10.25334/C1DA-G511

    Poster on cyberinfrastructure for the machine learning ere presented at the 2020 BIOME Institute: Cultivating Scientific Curiosity

  10. Cell Collective: Learning biology with modeling and simulations

    Cell Collective: Learning biology with modeling and simulations

    2020-07-27 14:21:35 | Teaching Materials | Contributor(s): Ehren Whigham, Tomas Helikar | doi:10.25334/GXHH-WF50

    Cell Collective is an online, research-grade modeling platform adapted to engage students in creating and simulating dynamic models of biological processes.

  11. Welcome to the BIOME Institute

    Welcome to the BIOME Institute

    2020-07-26 19:19:42 | Teaching Materials | Contributor(s): Kristin Jenkins | doi:10.25334/523B-7D89

    Slides for the BIOME Welcome on July 27, 2020

  12. Understanding Eukaryotic Genes modules: Glossary of terms

    Understanding Eukaryotic Genes modules: Glossary of terms

    2020-07-25 20:10:45 | Teaching Materials | Contributor(s): Meg Laakso, Carina Howell, Cathy Silver Key, Leocadia Paliulis, Maria S Santisteban, Chiyedza Small, Joyce Stamm, Elena Gracheva | doi:10.25334/C19B-4B88

    This glossary defines the key terms that are used in the Understanding Eukaryotic Genes modules.

  13. Module 6: Alternative Splicing

    Module 6: Alternative Splicing

    2020-07-25 20:07:57 | Teaching Materials | Contributor(s): Leocadia Paliulis, Anne Rosenwald | doi:10.25334/B3AH-GV62

    This module explores how multiple different mRNAs and polypeptides can be encoded by the same gene. After completing this module students will be able to explain how alternative splicing of a gene can lead to different mRNAs.

  14. Module 5: The Need for an Open Reading Frame

    Module 5: The Need for an Open Reading Frame

    2020-07-25 20:07:05 | Teaching Materials | Contributor(s): Carina Howell, Leocadia Paliulis, Anne Rosenwald | doi:10.25334/N11Z-PK53

    In this module, students will learn to identify the open reading frames for a given gene, and define the phases of the splice donor and acceptor sites.

  15. Module 4: Removal of Introns from pre-mRNA by Splicing

    Module 4: Removal of Introns from pre-mRNA by Splicing

    2020-07-25 20:06:06 | Teaching Materials | Contributor(s): Meg Laakso, Anne Rosenwald | doi:10.25334/030X-Q219

    In this module, students will learn to identify splice donor and acceptor sites that are best supported by RNA-Seq data, and use the canonical splice donor and splice acceptor sequences to identify intron-exon boundaries.

  16. Module 3: Transcription, Part II: What Happens to the Initial Transcript Made by RNA pol II?

    Module 3: Transcription, Part II: What Happens to the Initial Transcript Made by RNA pol II?

    2020-07-25 20:05:01 | Teaching Materials | Contributor(s): Cathy Silver Key, Chiyedza Small, Laura Reed | doi:10.25334/PYZN-JQ45

    This module teaches about the three key steps that are involved in converting the pre-mRNA into a mature mRNA: 1) The addition of a 5’ cap, 2) The addition of a 3’ poly(A) tail, 3) The removal of introns through splicing.

  17. Module 2: Transcription Part I: From DNA Sequence to Transcription Unit

    Module 2: Transcription Part I: From DNA Sequence to Transcription Unit

    2020-07-25 20:04:08 | Teaching Materials | Contributor(s): Maria Santisteban, Alexa Sawa | doi:10.25334/53EH-4602

    This module illustrates how a primary transcript (pre-mRNA) is synthesized using a DNA molecule as the template. Students will learn about the importance of the 5' and 3' regions of the gene for initiation and termination of transcription.

  18. Module 1: Introduction to the Genome Browser: What is a Gene?

    Module 1: Introduction to the Genome Browser: What is a Gene?

    2020-07-25 20:03:07 | Teaching Materials | Contributor(s): Joyce Stamm, Jennifer Kennell, Wilson Leung, Leocadia Paliulis, Srebrenka Robic, Anne Rosenwald | doi:10.25334/N0PH-7508

    This lesson introduces the University of California Santa Cruz genome browser to students, walking them through some of the key features so that it can be used for analysis of gene structure.

  19. GEA Introductory lesson on RNA-Seq

    GEA Introductory lesson on RNA-Seq

    2020-07-25 20:01:56 | Teaching Materials | Contributor(s): Jason Williams, Judy Brusslan, Ray Enke, Matthew Escobar, Vince Buonaccorsi | doi:10.25334/GM6A-VC81

    This RNA-Seq lesson uses the CyVerse VICE Platform and Jupyter notebooks to examine the expression of the leptin gene in samples from a mouse experimental design evaluating diet (high-fat vs. normal diet) and disease (cancer vs. normal tissue).

  20. GEA Introductory lesson on BLAST

    GEA Introductory lesson on BLAST

    2020-07-25 20:00:58 | Teaching Materials | Contributor(s): Justin DiAngelo, Alexis Nagengast, Wilson Leung, Douglas L Chalker | doi:10.25334/WQ1J-PW32

    The "Introduction to BLAST using Human Leptin" exercise aims to introduce students to the use of the Basic Local Alignment Search Tool (BLAST) to identify related sequences and compare similarity between them.