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CRISPR Gene Editing: Designing the gRNA and Donor Template
15 Jul 2020 | Teaching Materials | Contributor(s):
By Laurel Lorenz
In this adaptation, students learn how CRISPR/Cas9 is used in bacterial immunity and gene editing. Students create both a gRNA target and a donor template to edit a gene. Mutations can be from the...
12 Jun 2020 | Teaching Materials | Contributor(s):
By Laurel Lorenz1, Shuchismita Dutta2
1. Princeton University 2. RCSB Protein Data Bank, Rutgers University
This case focuses on understanding structure and function relationships in Piwi, a protein that is critical for germline stem cell function and development of eggs in the fruit fly ovary.