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Tags: C4. Bioinformatics tools

Description

C4. Use bioinformatics tools to examine complex biological problems in evolution, information flow, and other important areas of biology. This competency is written broadly so as to encompass a variety of problems that can be addressed using bioinformatics tools, such as understanding the evolutionary underpinnings of sequence comparison and homology detection; distinguishing between genomic sequences, RNA sequences, and protein sequences; and 
23 interpreting phylogenetic trees. “Complex” biological problems require that students should be able to work through a problem with multiple steps, not just perform isolated tasks. 

  • Using multiple lines of evidence, annotate a gene.
  • Develop and interpret a “tree of life” based on a BLAST search, multiple alignment, and
    phylogenetic-tree building.
  • Explain how a mutation in a gene causes cancer, using a genome browser to identify the gene, transcript, and affected protein, and tools such as OMIM, GO, and KEGG to place it in the context of a function and pathway important to the disease.

All Categories (41-41 of 41)

  1. RNA-seq Analysis

    03 Aug 2016 | Teaching Materials | Contributor(s):

    By Bill Morgan1, Matthew Reeder2

    1. The College of Wooster 2. Ohio State University

    In this computer lab module, students learn how to process an RNA-seq data set to identify differentially expressed genes (DEGs). The samples for this data set were collected from yeast cells...

    https://qubeshub.org/publications/27/?v=1