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1-102C-CancerGrowth-ModelingScenario
22 May 2022 | Teaching Materials | Contributor(s):
By Jennie D'Ambroise1, Jue Wang
SUNY Old Westbury, Old Westbury NY USA
This module guides students in the use of differential equation models to predict cancer growth and study treatment outcomes. Several classical models for cancer growth are presented including...
https://qubeshub.org/publications/3222/?v=1
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1-150-CancerTherapy-ModelingScenario
22 May 2022 | Teaching Materials | Contributor(s):
By Iordanka Panayotova1, Maila Hallare2
1. Christopher Newport University 2. NSU Math
This activity builds upon elementary models on population growth. In particular, we compare two different treatment models of cancer therapy where in one, surgery happens before therapy and in the...
https://qubeshub.org/publications/3195/?v=1
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1999-Peter_Deuflhard-Differential Equations in Technology and Medicine
26 Mar 2023 | Teaching Materials | Contributor(s):
By Peter Deuflhard
NA
It deals with a variety of challenging real life problems selected from clinical cancer therapy, communication technology, polymer production, and pharmaceutical drug design.
https://qubeshub.org/publications/3867/?v=1
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2012-Gilbert_Koch-Modeling of Pharmacokinetic and Pharmacodynamics of Cancer and Arthritis
07 Apr 2023 | Teaching Materials | Contributor(s):
By Gilbert Koch
NA
In this work we develop preclinical PKPD models based on fundamental biological and pharmacological principles. Equipped with a PKPD model, different dosing schedules could be simulated.
https://qubeshub.org/publications/4077/?v=1
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2014-Enderling-Chaplain-Mathematical Modeling of Tumor Growth and Treatment
08 Apr 2023 | Teaching Materials | Contributor(s):
By Heiko Enderling1, Mark Chaplain1
NA
Herein we describe fundamentals of mathematical modeling of tumor growth and tumor-host interactions, and summarize some of the seminal and most prominent approaches.
https://qubeshub.org/publications/4109/?v=1
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2015-Heiko_Enderling-Integrating experimental data to calibrate quantitative cancer models
08 Apr 2023 | Teaching Materials | Contributor(s):
By Heiko Enderling
NA
For quantitative cancer models to be meaningful and interpretable the number of unknown parameters must be kept minimal. We focus on a tumor hierarchy of cancer stem and progenitor non-stem cancer...
https://qubeshub.org/publications/4137/?v=1
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2016-Wilkie-EtAl-Using ODEs to Explore Cancer-Immune Dynamics and Tumor Dormancy
09 Apr 2023 | Teaching Materials | Contributor(s):
By Kathleen Wilkie
NA
Here we present a general method using ordinary differential equations (ODEs) to model and analyze cancer-immune interactions, and in particular, immune-induced tumor dormancy.
https://qubeshub.org/publications/4172/?v=1
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2020-Stepien_Kostelich_Kuang-Mathematics Cancer An Undergraduate Bridge Course in Applied Mathematics
07 Mar 2023 | Teaching Materials | Contributor(s):
By Tracy L. Stepien1, Eric J. Kostelich1, Yang Kuang1
NA
Most undergraduates have limited experience with mathematical modeling. This paper describes a course on the mathematical models of cancer growth and treatment.
https://qubeshub.org/publications/3730/?v=1
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6-017-OncolyticViruses-ModelingScenario
06 May 2022 | Teaching Materials | Contributor(s):
By Iordanka Panayotova1, Maila Brucal-Hallare2
1. Christopher Newport University, Newport News VA 23606 USA 2. Norfolk State University, Norfolk VA 23504 USA
Students explore oncolytic virotherapy using systems of differential equations and numerical simulations.
https://qubeshub.org/publications/2997/?v=1
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Ashlee Tietje
https://qubeshub.org/community/members/31419
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Bioimage Informatics Activity
26 Jul 2018 | Teaching Materials | Contributor(s):
By David Julian
Univ of Florida
Students use basic bioimage informatics techniques to acquire quantitative data from images of cultured cells and test a hypothesis about the effect of a genetic mutation on cellular phenotypes
https://qubeshub.org/publications/729/?v=1
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Building a Model of Tumorigenesis: A small group activity for a cancer biology/cell biology course
22 Aug 2021 | Teaching Materials | Contributor(s):
By Leslie Kate Wright
Rochester Institute of Technology
The multistep nature of tumorigenesis is a foundational concept in the context of Cancer Biology. Many students do not appreciate the complex nature of cancer development nor do they understand how...
https://qubeshub.org/publications/2536/?v=1
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Calculating Lifetime Cancer Risk Resulting from DNA Replication
18 Jan 2018 | Teaching Materials | Contributor(s):
By Rebecca Orr1, Ruth Buskirk2, Kristin Harvey2
1. Collin College 2. University of Texas at Austin
An expanded case study adapted from an HHMI Data Point on Cell Division and Cancer Risk using Figure 1 from Tomasetti, C. and Vogelstein, B. (2015).
https://qubeshub.org/publications/310/?v=1
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Cancer Discovery Activities
17 Jan 2018 | Teaching Materials | Contributor(s):
By HHMI BioInteractive
These two hands-on activities are based on a Howard Hughes Medical Institute 2013 Holiday Lectures on Science video (http://www.hhmi.org/biointeractive/cancer-genetic-disease-video-highlights)...
https://qubeshub.org/publications/294/?v=1
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Cell Division and Cancer Risk Data Point
17 Jan 2018 | Teaching Materials | Contributor(s):
By HHMI BioInteractive
Cancer is typically attributed to hereditary and environmental factors, but these only explain a fraction of overall cancer risk. This activity explores a third factor.
https://qubeshub.org/publications/299/?v=1
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Drug screening and cancer resistance: EGFR Activity
25 Jul 2018 | Teaching Materials | Contributor(s):
By Holly Basta
Rock Mountain College
This activity explores a specific gene (egfr) and its role in cancer. EGFR was introduced with the Gene Card Activities, researched throughout the semester, and then authentic image data of...
https://qubeshub.org/publications/720/?v=1
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Geoscience Methods and Resources for K-5 Pre-Education Majors
28 May 2018 | Teaching Materials | Contributor(s):
By James Burton Deemy
College of Coastal Georgia
: Exploring Geoscience Methods was an excellent capstone experience for Elementary Education Majors. The class I used this module with was 24 students of various backgrounds and academic...
https://qubeshub.org/publications/572/?v=1
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GMC: Genes, Mutations and Cancer - Group Concept Map Development
28 Aug 2021 | Teaching Materials | Contributor(s):
By Shoshana D. Katzman*1, John H. Horne2, Sonu S. Baral3, Keith P. Choe4, Elizabeth Eich5
1. Georgia Gwinnett College 2. University of New Orleans 3. Louisiana State University 4. University of Florida 5. Rice University
It has been shown that active learning strategies used in the classroom can increase student learning and retention of information. We generated an active learning exercise that can be used in the...
https://qubeshub.org/publications/2736/?v=1
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Heather Reed
https://qubeshub.org/community/members/8204
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Jillian F Wise
https://qubeshub.org/community/members/37675