Tags: central dogma

Resources (1-12 of 12)

  1. Central Dogma, Dictionaries, and Functions: Using Programming Concepts to Simulate Biological Processes

    21 Jun 2023 | Teaching Materials | Contributor(s):

    By Jyothi Kumar*1, Fabio Gomez-Cano†1, Seth W. Hunt†1, Serena G. Lotreck†1, Davis T. Mathieu†1, McKena L. Wilson†1, Tammy M. Long*1

    Michigan State University

    Technologies like next-generation sequencing, proteomics, and high-throughput phenotyping have transformed the way we do biology. There is a continued need for scientists with computational skills...

    https://qubeshub.org/publications/4356/?v=1

  2. Garden Variety Mutations: Using Primary Data to Understand the Central Dogma in Large-Lecture Introductory Biology

    22 Nov 2022 | Teaching Materials | Contributor(s):

    By Jacob Woodbury†1, Jessie B. Arneson†2, Jacey Anderson1, Larry Collins3, Andy Cavagnetto1, William Davis1, Erika G. Offerdahl*1

    1. Washington State University 2. University of Jamestown 3. Delta State University

    The ability to interpret and create an argument from data is a crucial skill for budding scientists, yet one that is seldom practiced in introductory courses. During this argumentation module,...

    https://qubeshub.org/publications/3559/?v=1

  3. A Muscular Dystrophy Case Study Illustrating the Phenotypic Effects of Mutation

    31 Oct 2022 | Teaching Materials | Contributor(s):

    By Lauren J. Hodkinson†1, Julia L. Gross†2, Leila E. Rieder*1

    1. Emory University 2. Emory University, National Institute of Allergy and Infectious Disease

    Mutations in genes can lead to a variety of phenotypes, including various human diseases. Students often understand that a particular mutation in a single gene causes a disease phenotype, but it is...

    https://qubeshub.org/publications/3558/?v=1

  4. Splicing it Together: Using Primary Data to Explore RNA Splicing and Gene Expression in Large-Lecture Introductory Biology

    28 Apr 2022 | Teaching Materials | Contributor(s):

    By Jessie B. Arneson1, Jacob Woodbury1, Jacey Anderson1, Larry B. Collins2, Andy Cavagnetto1, William B. Davis1, Erika G. Offerdahl*1

    1. Washington State University 2. Washington State University, Delta State University

    At the heart of scientific ways of knowing is the systematic collection and analysis of data, which is then used to propose an explanation of how the world works. In this two-day module, students...

    https://qubeshub.org/publications/2863/?v=1

  5. Teaching the Central Dogma Using a Case Study of Genetic Variation in Cystic Fibrosis

    27 Jan 2022 | Teaching Materials | Contributor(s):

    By Abby E. Hare-Harris

    Bloomsburg University

    The central dogma of biology is a foundational concept that is traditionally included in genetics curricula at all academic levels. Despite its ubiquitous presence throughout genetics education,...

    https://qubeshub.org/publications/2817/?v=1

  6. A clicker-based case study that untangles student thinking about the processes in the central dogma

    27 Aug 2021 | Teaching Materials | Contributor(s):

    By Karen Nicole Pelletreau1, Tessa Andrews2, Norris Armstrong2, Mary A Bedell2, Farahad Dastoor1, Neta Dean3, Susan Erster3, Cori Fata-Hartley4, Nancy Guild5, Hamish Greig1, David Hall2, Jennifer K Knight5, Donna Koslowsky4, Paula Lemons2, Jennifer Martin5, Jill McCourt2, John Merrill4, Rosa Moscarella4, Ross Nehm3, Robert Northington1, Brian Olsen1, Luanna Prevost6, Jon Stolzfus4, Mark Urban-Lurain4, Michelle K. Smith1

    1. University of Maine 2. University of Georgia 3. Stony Brook University 4. Michigan State University 5. University of Colorado Boulder 6. University of South Florida

    The central dogma of biology is a foundational concept that provides a scaffold to understand how genetic information flows in biological systems. Despite its importance, undergraduate students...

    https://qubeshub.org/publications/2577/?v=1

  7. Predicting and classifying effects of insertion and deletion mutations on protein coding regions

    26 Aug 2021 | Teaching Materials | Contributor(s):

    By Joseph Ross

    California State University, Fresno

    Mutations in genes can affect the encoded proteins in multiple ways, and some of these effects are counterintuitive. As for any other knowledge, students must create their own deep understanding of...

    https://qubeshub.org/publications/2569/?v=1

  8. Using computational molecular modeling software to demonstrate how DNA mutations cause phenotypes

    26 Aug 2021 | Teaching Materials | Contributor(s):

    By Tara Phelps-Durr

    Radford University

    Students require a deep understanding of the central dogma before they can understand complex topics such as evolution and biochemical disorders. However, getting undergraduate biology students to...

    https://qubeshub.org/publications/2563/?v=1

  9. Using Synthetic Biology and pClone Red for Authentic Research on Promoter Function: Genetics (analyzing mutant promoters)

    25 Aug 2021 | Teaching Materials | Contributor(s):

    By Todd T. Eckdahl1, A. Malcolm Campbell2

    1. Missouri Western State University 2. Davidson College

    Students often memorize the definition of a transcriptional promoter but fail to fully understand the critical role promoters play in gene expression.  This laboratory lesson allows students...

    https://qubeshub.org/publications/2551/?v=1

  10. Using Synthetic Biology and pClone Red for Authentic Research on Promoter Function: Introductory Biology (identifying new promoters)

    24 Aug 2021 | Teaching Materials | Contributor(s):

    By A. Malcolm Campbell1, Todd T. Eckdahl2

    1. Davidson College 2. Missouri Western State University

    Students often memorize the definition of a transcriptional promoter but fail to fully understand the critical role promoters play in gene expression. This laboratory lesson allows students to...

    https://qubeshub.org/publications/2547/?v=1

  11. Building creatures with the central dogma of biology

    02 Dec 2019 | Teaching Materials | Contributor(s):

    By Melissa Skyer

    National Technical Institute for the Deaf at Rochester Institute of Technology

    Activity that demonstrates how nucleotide changes can affect phenotypes

    https://qubeshub.org/publications/1445/?v=1

  12. Using computational molecular modeling software to demonstrate how DNA mutations cause phenotypes

    04 Jan 2019 | Teaching Materials | Contributor(s):

    By Tara Phelps-Durr

    Radford University

    This lesson is a five-week series of laboratory activities designed to help students transition from applying lower order thinking skills to the central dogma to applying higher-order thinking skills.

    https://qubeshub.org/publications/1006/?v=1