All Categories (1-20 of 25)

1. Maria vs Malaria - AR Adaptation

   04 Nov 2023 | Teaching Materials | Contributor(s):

   By Didem Vardar-Ulu¹, Saif Eldeen Ragab¹, Swati Agrawal²

   1. Boston University, Chemistry Department 2. University of Mary Washington

   This case study focuses on a specific enzyme Lactate Dehydrogenase (LDH) in the malarial parasite as a target for treating malaria. Students will be able to view selected molecular views from the...

   https://qubeshub.org/publications/4554/?v=1

2. Maria vs Malaria

   02 Nov 2023 | Teaching Materials | Contributor(s):

   By Didem Vardar-Ulu¹, Serena Yu¹, Alicia Lau¹, Molly Szpakowski¹

   Boston University

   This case study focuses on a specific enzyme Lactate Dehydrogenase (LDH) in the malarial parasite as a target for treating malaria.

   https://qubeshub.org/publications/4551/?v=1

3. Ecology/Environmental Biology Molecular Case Studies for Molecular CaseNet - YouTube

   06 Dec 2021 | Teaching Materials | Contributor(s):

   By Debra Linton¹, Heather Simpson², Jennifer Glee Buntz², Sheela Vemu³, Shuchismita Dutta⁴

   1. Central Michigan University 2. Central New Mexico Community College 3. Waubonsee Community College - Tenure Track and Northern Illinois University 4. RCSB Protein Data Bank, Rutgers University

   Biome Institute 2021, Fall Working Group Summary Video

   https://qubeshub.org/publications/2816/?v=1

4. Mol* Adaptation: Case of Severe Insulin Resistance

   23 Jul 2021 | Teaching Materials | Contributor(s):

   By Keith A. Johnson

   Bradley University College of Liberal Arts and Sciences

   This is an adaptation using Mol* on the original case written. This case focuses on understanding how a mutation in a cell signalling protein (a kinase) can prevent insulin function and lead to...

   https://qubeshub.org/publications/2483/?v=1

5. Students Authoring Molecular Case Studies

   22 Jul 2021 | Teaching Materials | Contributor(s):

   By Elizabeth Pollock¹, Kasandra Riley (She/Her)², Didem Vardar-Ulu³, Shuchismita Dutta⁴

   1. Stockton University 2. Rollins College 3. Boston University, Chemistry Department 4. RCSB Protein Data Bank, Rutgers University

   Poster on using case studies to help students develop their skills in reading primary literature and identifying authentic scientific problems by authoring their own case studies. Presented at the...

   https://qubeshub.org/publications/2466/?v=1

6. Happy Blue Baby

   09 Jun 2021 | Teaching Materials | Contributor(s):

   By Didem Vardar-Ulu

   Boston University, Chemistry Department

   This case, about a specific mutant of hemoglobin, focuses on visualizing and understanding the molecular basis of why an infant turned blue soon after birth and how the cyanosis resolved on its own...

   https://qubeshub.org/publications/2419/?v=1

7. COVID-19: Molecular Basis Infection Revisited One Year into the Pandemic

   09 Jun 2021 | Teaching Materials | Contributor(s):

   By Didem Vardar-Ulu

   Boston University, Chemistry Department

   This adaptation was written in Spring 2021 exactly one year after the original case and includes explorations of the emerging mutations within the spike protein

   https://qubeshub.org/publications/2424/?v=1

8. Waking up Anna - Adaptations and Conversion to Mol*

   08 Jun 2021 | Teaching Materials | Contributor(s):

   By Keith A. Johnson

   Bradley University College of Liberal Arts and Sciences

   This case focuses on understanding the molecular basis of Anna's sleeping disorder and its treatment.The adaptations addressed question clarity and reformatting to use Mol*.

   https://qubeshub.org/publications/2420/?v=1

9. Hemoglobin bioinformatics

   07 Jun 2021 | Teaching Materials | Contributor(s):

   By Keith A. Johnson

   Bradley University College of Liberal Arts and Sciences

   This is an introduction to bioinformatics using hemoglobin as an example. The worksheets introduce students to resources to explore the DNA, RNA and polypeptide linear structure with a brief...

   https://qubeshub.org/publications/2416/?v=1

10. Happy Blue Baby: MCQs for large classes

    18 May 2021 | Teaching Materials | Contributor(s):

    By "KP" Kristen Procko

    The University of Texas at Austin

    Multiple choice questions for the Happy Blue Baby case study pre-work

    https://qubeshub.org/publications/2381/?v=1

11. Molecular CaseNet - Developing Intro Tutorials - YouTube

    03 Dec 2020 | Teaching Materials | Contributor(s):

    By Jean Cardinale¹, Keith A. Johnson², Marie C. Montes-Matias³, Natalie Stringer⁴, Aeisha Thomas⁵, Shuchismita Dutta⁶

    1. Alfred University 2. Bradley University College of Liberal Arts and Sciences 3. Union County College 4. LabArchives, LLC 5. Crown College 6. RCSB Protein Data Bank, Rutgers University

    Biome Institute 2020, Summary Video

    https://qubeshub.org/publications/2157/?v=1

12. Molecular CaseNet - Students Writing Cases - YouTube

    03 Dec 2020 | Teaching Materials | Contributor(s):

    By Didem Vardar-Ulu¹, Elizabeth Pollock², Kasandra Riley (She/Her)³, Nik Tsotakos⁴, Swati Agrawal⁵, Shuchismita Dutta⁶

    1. Boston University, Chemistry Department 2. Stockton University 3. Rollins College 4. Penn State Harrisburg 5. University of Mary Washington 6. RCSB Protein Data Bank, Rutgers University

    Biome Institute 2020, Summary Video

    https://qubeshub.org/publications/2158/?v=1

13. CRISPR Gene Editing: Designing the gRNA and Donor Template

    15 Jul 2020 | Teaching Materials | Contributor(s):

    By Laurel Lorenz

    Princeton

    In this adaptation, students learn how CRISPR/Cas9 is used in bacterial immunity and gene editing. Students create both a gRNA target and a donor template to edit a gene. Mutations can be from the...

    https://qubeshub.org/publications/1962/?v=1

14. Sickle Cell Anemia using Nicholas’ Story

    25 Jun 2020 | Teaching Materials | Contributor(s):

    By Sharon Cisneros

    Malcolm X College

    The goal of this exercise is to introduce students to 3-D structures of biological molecules, visualize and manipulate them to understand their functions. The exercise also helps them see the...

    https://qubeshub.org/publications/1943/?v=1

15. COVID-19: Molecular Basis of Infection-ADAPTATION

    17 Jun 2020 | Teaching Materials | Contributor(s):

    By Didem Vardar-Ulu

    Boston University, Chemistry Department

    This case was written in Spring 2020 during the COVID-19 pandemic. It focuses on understanding the structure and interaction of the SARS-Cov-2 viral spike protein that facilitates infection in...

    https://qubeshub.org/publications/1936/?v=1

16. Molecular Basis of Sickle Cell Disease

    15 Jun 2020 | Teaching Materials | Contributor(s):

    By Didem Vardar-Ulu

    Boston University, Chemistry Department

    This multi part case on hemoglobin structure as it relates to oxygen binding and sickle cell disease focuses on utilizing bioinformatics and molecular visualization tools to learn about the sickle...

    https://qubeshub.org/publications/1925/?v=1

17. The Happy Blue Baby Hemoglobin

    14 Jun 2020 | Teaching Materials | Contributor(s):

    By Kasandra Jean-Louise Riley¹, Shuchismita Dutta²

    1. Rollins College 2. RCSB Protein Data Bank, Rutgers University

    This case, about a specific mutant of hemoglobin, focuses on visualizing and understanding the molecular basis of why an infant turned blue soon after birth and how the cyanosis resolved.

    https://qubeshub.org/publications/1924/?v=1

18. Nicholas' Story

    13 Jun 2020 | Teaching Materials | Contributor(s):

    By Nik Tsotakos

    Penn State Harrisburg

    This 3 part case on sickle cell disease focuses on visualizing and understanding the molecular basis of its cause, symptoms, complications, management, treatment, and possible cures.

    https://qubeshub.org/publications/1919/?v=1

19. COVID-19: Molecular Basis of Infection

    12 Jun 2020 | Teaching Materials | Contributor(s):

    By Didem Vardar-Ulu¹, Shuchismita Dutta²

    1. Boston University 2. RCSB Protein Data Bank, Rutgers University

    This case was written in Spring 2020 during the COVID-19 pandemic. It focuses on understanding the structure and interaction of the SARS-Cov-2 viral spike protein that facilitates infection in...

    https://qubeshub.org/publications/1912/?v=1

20. A Case of Severe Insulin Resistance

    12 Jun 2020 | Teaching Materials | Contributor(s):

    By Melanie Lenahan¹, Shuchismita Dutta²

    1. Raritan Valley Community College 2. RCSB Protein Data Bank, Rutgers University

    This case focuses on understanding how a mutation in a cell signalling protein (a kinase) can prevent insulin function and lead to diabetes.

    https://qubeshub.org/publications/1911/?v=1