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Tags: mutation

All Categories (1-20 of 21)

  1. A clicker-based case study that untangles student thinking about the processes in the central dogma

    27 Aug 2021 | Teaching Materials | Contributor(s):

    By Karen Nicole Pelletreau1, Tessa Andrews2, Norris Armstrong2, Mary A Bedell2, Farahad Dastoor1, Neta Dean3, Susan Erster3, Cori Fata-Hartley4, Nancy Guild5, Hamish Greig1, David Hall2, Jennifer K Knight5, Donna Koslowsky4, Paula Lemons2, Jennifer Martin5, Jill McCourt2, John Merrill4, Rosa Moscarella4, Ross Nehm3, Robert Northington1, Brian Olsen1, Luanna Prevost6, Jon Stolzfus4, Mark Urban-Lurain4, Michelle K. Smith1

    1. University of Maine 2. University of Georgia 3. Stony Brook University 4. Michigan State University 5. University of Colorado Boulder 6. University of South Florida

    The central dogma of biology is a foundational concept that provides a scaffold to understand how genetic information flows in biological systems. Despite its importance, undergraduate students...

    https://qubeshub.org/publications/2577/?v=1

  2. Avida-ED resources

    Collections | 18 Jul 2017 | Posted by Cory Kohn

    https://qubeshub.org/community/groups/summer2017/collections/resources-for-monday-sessions

  3. Converting a Face-to-Face Lab to Online: An Example of Process and Outcomes for a CRISPR-Based Molecular Biology Lab

    30 Aug 2021 | Teaching Materials | Contributor(s):

    By Lisa M. McDonnell #*1, Keefe Reuther #1, Andrew Cooper1, Christopher Day1, Cindy Gustafson-Brown1

    University of California, San Diego

    The COVID-19 pandemic created a need to convert in-person laboratory courses into an online format in a short amount of time. For this reason, we converted our face-to-face molecular biology lab...

    https://qubeshub.org/publications/2731/?v=1

  4. CRISPR Gene Editing: Designing the gRNA and Donor Template

    15 Jul 2020 | Teaching Materials | Contributor(s):

    By Laurel Lorenz

    Princeton

    In this adaptation, students learn how CRISPR/Cas9 is used in bacterial immunity and gene editing. Students create both a gRNA target and a donor template to edit a gene. Mutations can be from the...

    https://qubeshub.org/publications/1962/?v=1

  5. Exploring Random Mutation and Selection: Avida-Ed Lab Book Exercise 2

    17 May 2020 | Teaching Materials | Contributor(s):

    By Amy Lark, Cory Kohn1, Jim Smith1, Louise Mead2, Robert T Pennock1, Wendy Johnson

    1. Michigan State University 2. BEACON Center for the Study of Evolution in Action

    An introductory activity exploring the role of random mutation in natural selection using the Avida-ED simulation.

    https://qubeshub.org/publications/1847/?v=1

  6. Exploring the Introduction of Genetic Variation by Random Mutation: Avida-Ed Lab Book Exercise 1

    17 May 2020 | Teaching Materials | Contributor(s):

    By Cory Kohn1, Amy Lark, Jim Smith2, Louise Mead3, Robert T Pennock2, Wendy Johnson

    1. Keck Science Department, The Claremont Colleges 2. Michigan State University 3. BEACON Center for the Study of Evolution in Action

    An introductory activity introducing the role of random mutation in generating genetic variation using the Avida-ED simulation.

    https://qubeshub.org/publications/1840/?v=1

  7. GMC: Genes, Mutations and Cancer - Group Concept Map Development

    28 Aug 2021 | Teaching Materials | Contributor(s):

    By Shoshana D. Katzman*1, John H. Horne2, Sonu S. Baral3, Keith P. Choe4, Elizabeth Eich5

    1. Georgia Gwinnett College 2. University of New Orleans 3. Louisiana State University 4. University of Florida 5. Rice University

    It has been shown that active learning strategies used in the classroom can increase student learning and retention of information. We generated an active learning exercise that can be used in the...

    https://qubeshub.org/publications/2736/?v=1

  8. Happy Blue Baby

    11 Jun 2020 | Teaching Materials | Contributor(s):

    By Shuchismita Dutta

    RCSB Protein Data Bank, Rutgers University

    This case, about a specific mutant of hemoglobin, focuses on visualizing and understanding the molecular basis of why an infant turned blue soon after birth and how the cyanosis resolved on its own...

    https://qubeshub.org/publications/1902/?v=1

  9. Happy Blue Baby

    09 Jun 2021 | Teaching Materials | Contributor(s):

    By Didem Vardar-Ulu

    Boston University, Chemistry Department

    This case, about a specific mutant of hemoglobin, focuses on visualizing and understanding the molecular basis of why an infant turned blue soon after birth and how the cyanosis resolved on its own...

    https://qubeshub.org/publications/2419/?v=1

  10. Happy Blue Baby: MCQs for large classes

    18 May 2021 | Teaching Materials | Contributor(s):

    By "KP" Kristen Procko

    Multiple choice questions for the Happy Blue Baby case study pre-work

    https://qubeshub.org/publications/2381/?v=1

  11. Joel E. Greengiant Learns About Peas: From Nucleotides to Selection

    23 Oct 2018 | Teaching Materials | Contributor(s):

    By Merle Heidemann1, Peter J.T. White1, Jim Smith1

    Michigan State University

    This case study follows purveyors of peas, Joel E. and Jolene Greengiant, as they learn about the origin, biochemistry, genetics and eventual artificial selection of sweet (wrinkled) peas, all in...

    https://qubeshub.org/publications/845/?v=1

  12. Joel E. Greengiant Learns About Peas: From Nucleotides to Selection

    17 Jun 2015 | | Contributor(s):: Merle Heidemann, Peter J.T. White, Jim Smith

    This resource has been updated - find the current version here: https://qubeshub.org/qubesresources/publications/845This case study follows purveyors of peas, Joel E. and Jolene Greengiant, as they learn about the origin, biochemistry, genetics and eventual artificial selection of sweet...

  13. Linking Genotype to Phenotype: The Effect of a Mutation in Gibberellic Acid Production on Plant Germination

    27 Aug 2021 | Teaching Materials | Contributor(s):

    By James W. Mann1, Jennifer Larson2, Marcelo Pomeranz1, Emma M. Knee1, Diana Shin1, Julie A. Miller1, Courtney G. Price1, Deborah K. Crist1, Erich Grotewold1, Jelena Brkljacic1

    1. The Ohio State University 2. Capital University

    Basic concepts in genetics and plant development are often taught in lecture courses without a lab component. This approach provides students with the content knowledge, but fails to make...

    https://qubeshub.org/publications/2596/?v=1

  14. Luria-Delbruck

    14 Sep 2015 | | Contributor(s):: Tony Weisstein, John R Jungck, Doug Green

    This resource has been updated - find the current version here: https://qubeshub.org/qubesresources/publications/777These two workbooks model the evolution of phage resistance in a bacterial population under two alternative hypotheses. Under the hypothesis of acquired immunity, mutation...

  15. Mutation and Selection: An Exploration of Antibiotic Resistance in Serratia marcescens

    15 Sep 2016 | | Contributor(s):: Laurel Hester, Mark Sarvary, Corey Ptak

    This resource has been updated - find the current version here:  https://qubeshub.org/qubesresources/publications/875I published this paper with Mark Sarvary and Corey Ptak in the 2014 Proceedings of the Association for Biology Laboratory Education based on a laboratory module we...

  16. Mutation and Selection: An Exploration of Antibiotic Resistance in Serratia Marcescens

    25 Oct 2018 | Teaching Materials | Contributor(s):

    By Laurel Hester1, Mark Sarvary2, Corey Ptak

    1. Keuka College 2. Cornell University

    This laboratory module gives students hands-on experience with mutation and selection in bacteria.

    https://qubeshub.org/publications/875/?v=1

  17. Predicting and classifying effects of insertion and deletion mutations on protein coding regions

    26 Aug 2021 | Teaching Materials | Contributor(s):

    By Joseph Ross

    California State University, Fresno

    Mutations in genes can affect the encoded proteins in multiple ways, and some of these effects are counterintuitive. As for any other knowledge, students must create their own deep understanding of...

    https://qubeshub.org/publications/2569/?v=1

  18. Selection and the Blond Beach Mouse

    12 Nov 2018 | Teaching Materials | Contributor(s):

    By Joan Sharp

    Simon Fraser University

    National Center for Case Study Teaching in Science- this "clicker" case study explores ultimate and proximate explanations for cryptic coloration in animals.

    https://qubeshub.org/publications/921/?v=1

  19. The Happy Blue Baby Hemoglobin

    14 Jun 2020 | Teaching Materials | Contributor(s):

    By Kasandra Jean-Louise Riley1, Shuchismita Dutta2

    1. Rollins College 2. RCSB Protein Data Bank, Rutgers University

    This case, about a specific mutant of hemoglobin, focuses on visualizing and understanding the molecular basis of why an infant turned blue soon after birth and how the cyanosis resolved.

    https://qubeshub.org/publications/1924/?v=1

  20. Web Popgen

    11 Jun 2017 | | Contributor(s):: Bob Sheehy

    This resource has been updated - find the current version here: https://qubeshub.org/qubesresources/publications/842A Hardy-Weinberg based population genetics simulator. This program assumes a single gene and two alleles. Simulation of allele frequency changes similar to...