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  1. Holly Martin

    https://qubeshub.org/community/members/43508

  2. Fragile States: A Case Study Exploring Genetics, Molecular Biology, and Biochemistry Through the Lens of Fragile X Syndrome

    24 Aug 2023 | Teaching Materials | Contributor(s):

    By Amy T. Hark*1, Lauren E. Washco1

    Muhlenberg College

    This case aims to strengthen students’ understanding of molecular biology concepts through study of Fragile X Syndrome (FXS). Students begin by learning the cause and phenotypes of FXS and...

    https://qubeshub.org/publications/4510/?v=1

  3. How to Find a Gene: Retrieving Information From Gene Databases

    23 Feb 2023 | Teaching Materials | Contributor(s):

    By Ah Rume Julie Park†1, Maitreyi Upadhyay†1, William J. Anderson1, Amie L. Holmes*1

    Harvard University, Harvard Stem Cell Institute

    A strong understanding of distinct gene components and the ability to retrieve relevant information from gene databases are necessary to answer a diverse set of biological questions. However, often...

    https://qubeshub.org/publications/3672/?v=1

  4. Garden Variety Mutations: Using Primary Data to Understand the Central Dogma in Large-Lecture Introductory Biology

    22 Nov 2022 | Teaching Materials | Contributor(s):

    By Jacob Woodbury†1, Jessie B. Arneson†2, Jacey Anderson1, Larry Collins3, Andy Cavagnetto1, William Davis1, Erika G. Offerdahl*1

    1. Washington State University 2. University of Jamestown 3. Delta State University

    The ability to interpret and create an argument from data is a crucial skill for budding scientists, yet one that is seldom practiced in introductory courses. During this argumentation module,...

    https://qubeshub.org/publications/3559/?v=1

  5. Metastatic Mastery: A Case and Game-Based Approach to Learning About Cancer Mechanisms

    07 Aug 2022 | Teaching Materials | Contributor(s):

    By Sayali Kukday*1, Emilyn Frohn2, Alice Paige3

    1. Iowa State University 2. Biomedical Animator 3. Fiction Author and Essayist

    Mechanisms that contribute to the development of cancer are numerous and complicated, though most can be traced to a set of mutations in cell cycle regulatory genes that throw the process of cell...

    https://qubeshub.org/publications/3420/?v=1

  6. Splicing it Together: Using Primary Data to Explore RNA Splicing and Gene Expression in Large-Lecture Introductory Biology

    28 Apr 2022 | Teaching Materials | Contributor(s):

    By Jessie B. Arneson1, Jacob Woodbury1, Jacey Anderson1, Larry B. Collins2, Andy Cavagnetto1, William B. Davis1, Erika G. Offerdahl*1

    1. Washington State University 2. Washington State University, Delta State University

    At the heart of scientific ways of knowing is the systematic collection and analysis of data, which is then used to propose an explanation of how the world works. In this two-day module, students...

    https://qubeshub.org/publications/2863/?v=1

  7. Teaching the Central Dogma Using a Case Study of Genetic Variation in Cystic Fibrosis

    27 Jan 2022 | Teaching Materials | Contributor(s):

    By Abby E. Hare-Harris

    Bloomsburg University

    The central dogma of biology is a foundational concept that is traditionally included in genetics curricula at all academic levels. Despite its ubiquitous presence throughout genetics education,...

    https://qubeshub.org/publications/2817/?v=1

  8. Targeting Misconceptions in the Central Dogma by Examining Viral Infection

    22 Oct 2021 | Teaching Materials | Contributor(s):

    By Stefanie R. DeVito*

    University of Delaware

    Understanding the central dogma and how changes in gene expression can impact cell function requires integration of several topics in molecular biology. Students often do not make the necessary...

    https://qubeshub.org/publications/2765/?v=1

  9. Converting a Face-to-Face Lab to Online: An Example of Process and Outcomes for a CRISPR-Based Molecular Biology Lab

    30 Aug 2021 | Teaching Materials | Contributor(s):

    By Lisa M. McDonnell #*1, Keefe Reuther #1, Andrew Cooper1, Christopher Day1, Cindy Gustafson-Brown1

    University of California, San Diego

    The COVID-19 pandemic created a need to convert in-person laboratory courses into an online format in a short amount of time. For this reason, we converted our face-to-face molecular biology lab...

    https://qubeshub.org/publications/2731/?v=1

  10. Investigating Gene Expression and Cell Specialization in Axolotl Embryos

    29 Aug 2021 | Teaching Materials | Contributor(s):

    By Deborah Eastman*

    Connecticut College

    The process of cell specialization is critical to the formation and function of tissues in animals and plants. Although gene expression, including the regulation of transcription, is taught in most...

    https://qubeshub.org/publications/2671/?v=1

  11. Investigating Cell Signaling with Gene Expression Datasets

    28 Aug 2021 | Teaching Materials | Contributor(s):

    By James M. Wachira1, Cleo A. Hughes-Darden1, Asamoah Nkwanta1

    Morgan State University

    Modern molecular biology is a data- and computationally-intensive field with few instructional resources for introducing undergraduate students to the requisite skills and techniques for analyzing...

    https://qubeshub.org/publications/2618/?v=1

  12. A clicker-based case study that untangles student thinking about the processes in the central dogma

    27 Aug 2021 | Teaching Materials | Contributor(s):

    By Karen Nicole Pelletreau1, Tessa Andrews2, Norris Armstrong2, Mary A Bedell2, Farahad Dastoor1, Neta Dean3, Susan Erster3, Cori Fata-Hartley4, Nancy Guild5, Hamish Greig1, David Hall2, Jennifer K Knight5, Donna Koslowsky4, Paula Lemons2, Jennifer Martin5, Jill McCourt2, John Merrill4, Rosa Moscarella4, Ross Nehm3, Robert Northington1, Brian Olsen1, Luanna Prevost6, Jon Stolzfus4, Mark Urban-Lurain4, Michelle K. Smith1

    1. University of Maine 2. University of Georgia 3. Stony Brook University 4. Michigan State University 5. University of Colorado Boulder 6. University of South Florida

    The central dogma of biology is a foundational concept that provides a scaffold to understand how genetic information flows in biological systems. Despite its importance, undergraduate students...

    https://qubeshub.org/publications/2577/?v=1

  13. Using Synthetic Biology and pClone Red for Authentic Research on Promoter Function: Genetics (analyzing mutant promoters)

    25 Aug 2021 | Teaching Materials | Contributor(s):

    By Todd T. Eckdahl1, A. Malcolm Campbell2

    1. Missouri Western State University 2. Davidson College

    Students often memorize the definition of a transcriptional promoter but fail to fully understand the critical role promoters play in gene expression.  This laboratory lesson allows students...

    https://qubeshub.org/publications/2551/?v=1

  14. Using Synthetic Biology and pClone Red for Authentic Research on Promoter Function: Introductory Biology (identifying new promoters)

    24 Aug 2021 | Teaching Materials | Contributor(s):

    By A. Malcolm Campbell1, Todd T. Eckdahl2

    1. Davidson College 2. Missouri Western State University

    Students often memorize the definition of a transcriptional promoter but fail to fully understand the critical role promoters play in gene expression. This laboratory lesson allows students to...

    https://qubeshub.org/publications/2547/?v=1

  15. A Hands-on Introduction to Hidden Markov Models

    24 Aug 2021 | Teaching Materials | Contributor(s):

    By Anton E. Weisstein1, Elena Gracheva2, Zane Goodwin2, Zongtai Qi2, Wilson Leung2, Christopher D. Shaffer2, Sarah C.R. Elgin2

    1. Truman State University 2. Washington University in St. Louis

    In this Lesson, we describe a classroom activity that demonstrates how a Hidden Markov Model (HMM) is applied to predict a eukaryotic gene, focusing on predicting one exon-intron boundary. This HMM...

    https://qubeshub.org/publications/2562/?v=1

  16. Terrie Rife

    https://qubeshub.org/community/members/16708

  17. Intro videos and terminology for GMOs, Transcription, Translation

    28 Oct 2019 | Teaching Materials | Contributor(s):

    By Sandi Connelly

    Rochester Institute Of Technology

    Compiled resources around GMOs and protein production including vocabulary, animations, videos, and games

    https://qubeshub.org/publications/1446/?v=1

  18. Intro videos and terminology for GMOs, Transcription, Translation

    Collections | 29 Sep 2019 | Posted by Sandi Connelly

    https://qubeshub.org/community/groups/opening_the_pathway/collections/resources-for-the-case-study

  19. FIGUEROA BOSSI Nara

    https://qubeshub.org/community/members/10869

  20. A Hands-on Introduction to Hidden Markov Models

    04 Jan 2019 | Teaching Materials | Contributor(s):

    By Tony Weisstein1, Elena Gracheva2, Zane Goodwin2, Zongtai Qi2, Wilson Leung2, Christopher D. Shaffer2, Sarah C.R. Elgin2

    1. Truman State University 2. Washington University in St. Louis

    A lesson in which students will understand the basic structure of an HMM, the types of data used in ab initio gene prediction, and its consequent limitations.

    https://qubeshub.org/publications/999/?v=1

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