All Categories (1-11 of 11)

1. Fragile States: A Case Study Exploring Genetics, Molecular Biology, and Biochemistry Through the Lens of Fragile X Syndrome

   24 Aug 2023 | Teaching Materials | Contributor(s):

   By Amy T. Hark*¹, Lauren E. Washco¹

   Muhlenberg College

   This case aims to strengthen students’ understanding of molecular biology concepts through study of Fragile X Syndrome (FXS). Students begin by learning the cause and phenotypes of FXS and...

   https://qubeshub.org/publications/4510/?v=1

2. How to Find a Gene: Retrieving Information From Gene Databases

   23 Feb 2023 | Teaching Materials | Contributor(s):

   By Ah Rume Julie Park†¹, Maitreyi Upadhyay†¹, William J. Anderson¹, Amie L. Holmes*¹

   Harvard University, Harvard Stem Cell Institute

   A strong understanding of distinct gene components and the ability to retrieve relevant information from gene databases are necessary to answer a diverse set of biological questions. However, often...

   https://qubeshub.org/publications/3672/?v=1

3. Garden Variety Mutations: Using Primary Data to Understand the Central Dogma in Large-Lecture Introductory Biology

   22 Nov 2022 | Teaching Materials | Contributor(s):

   By Jacob Woodbury†¹, Jessie B. Arneson†², Jacey Anderson¹, Larry Collins³, Andy Cavagnetto¹, William Davis¹, Erika G. Offerdahl*¹

   1. Washington State University 2. University of Jamestown 3. Delta State University

   The ability to interpret and create an argument from data is a crucial skill for budding scientists, yet one that is seldom practiced in introductory courses. During this argumentation module,...

   https://qubeshub.org/publications/3559/?v=1

4. Metastatic Mastery: A Case and Game-Based Approach to Learning About Cancer Mechanisms

   07 Aug 2022 | Teaching Materials | Contributor(s):

   By Sayali Kukday*¹, Emilyn Frohn², Alice Paige³

   1. Iowa State University 2. Biomedical Animator 3. Fiction Author and Essayist

   Mechanisms that contribute to the development of cancer are numerous and complicated, though most can be traced to a set of mutations in cell cycle regulatory genes that throw the process of cell...

   https://qubeshub.org/publications/3420/?v=1

5. Teaching the Central Dogma Using a Case Study of Genetic Variation in Cystic Fibrosis

   27 Jan 2022 | Teaching Materials | Contributor(s):

   By Abby E. Hare-Harris

   Bloomsburg University

   The central dogma of biology is a foundational concept that is traditionally included in genetics curricula at all academic levels. Despite its ubiquitous presence throughout genetics education,...

   https://qubeshub.org/publications/2817/?v=1

6. Targeting Misconceptions in the Central Dogma by Examining Viral Infection

   22 Oct 2021 | Teaching Materials | Contributor(s):

   By Stefanie R. DeVito*

   University of Delaware

   Understanding the central dogma and how changes in gene expression can impact cell function requires integration of several topics in molecular biology. Students often do not make the necessary...

   https://qubeshub.org/publications/2765/?v=1

7. Converting a Face-to-Face Lab to Online: An Example of Process and Outcomes for a CRISPR-Based Molecular Biology Lab

   30 Aug 2021 | Teaching Materials | Contributor(s):

   By Lisa M. McDonnell #*¹, Keefe Reuther #¹, Andrew Cooper¹, Christopher Day¹, Cindy Gustafson-Brown¹

   University of California, San Diego

   The COVID-19 pandemic created a need to convert in-person laboratory courses into an online format in a short amount of time. For this reason, we converted our face-to-face molecular biology lab...

   https://qubeshub.org/publications/2731/?v=1

8. A clicker-based case study that untangles student thinking about the processes in the central dogma

   27 Aug 2021 | Teaching Materials | Contributor(s):

   By Karen Nicole Pelletreau¹, Tessa Andrews², Norris Armstrong², Mary A Bedell², Farahad Dastoor¹, Neta Dean³, Susan Erster³, Cori Fata-Hartley⁴, Nancy Guild⁵, Hamish Greig¹, David Hall², Jennifer K Knight⁵, Donna Koslowsky⁴, Paula Lemons², Jennifer Martin⁵, Jill McCourt², John Merrill⁴, Rosa Moscarella⁴, Ross Nehm³, Robert Northington¹, Brian Olsen¹, Luanna Prevost⁶, Jon Stolzfus⁴, Mark Urban-Lurain⁴, Michelle K. Smith¹

   1. University of Maine 2. University of Georgia 3. Stony Brook University 4. Michigan State University 5. University of Colorado Boulder 6. University of South Florida

   The central dogma of biology is a foundational concept that provides a scaffold to understand how genetic information flows in biological systems. Despite its importance, undergraduate students...

   https://qubeshub.org/publications/2577/?v=1

9. Predicting and classifying effects of insertion and deletion mutations on protein coding regions

   26 Aug 2021 | Teaching Materials | Contributor(s):

   By Joseph Ross

   California State University, Fresno

   Mutations in genes can affect the encoded proteins in multiple ways, and some of these effects are counterintuitive. As for any other knowledge, students must create their own deep understanding of...

   https://qubeshub.org/publications/2569/?v=1

10. Intro videos and terminology for GMOs, Transcription, Translation

    28 Oct 2019 | Teaching Materials | Contributor(s):

    By Sandi Connelly

    Rochester Institute Of Technology

    Compiled resources around GMOs and protein production including vocabulary, animations, videos, and games

    https://qubeshub.org/publications/1446/?v=1

11. Intro videos and terminology for GMOs, Transcription, Translation

    Collections | 29 Sep 2019 | Posted by Sandi Connelly

    https://qubeshub.org/community/groups/opening_the_pathway/collections/resources-for-the-case-study