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Homologous chromosomes? Exploring human sex chromosomes, sex determination and sex reversal using bioinformatics approaches

Author(s): Kelsey Metzger

University of Minnesota, Rochester

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Summary:
In this four- part guided activity, students will learn about the structure and function of human autosomal and sex chromosomes, view and interpret gene maps, and gain familiarity with basic bioinformatics resources and data through use of the...

Licensed under CC Attribution-NonCommercial-ShareAlike 4.0 International according to these terms

Version 1.0 - published on 04 Jan 2019 doi:10.25334/Q4TT7Q - cite this

Keywords

  1. bioinformatics
  2. NIBLSE
  3. CourseSource
  4. autosome
  5. homologous chromosomes
  6. homologous recombination
  7. sex chromosome
  8. sex determination
  9. sex reversal mutations

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  2. Audience Level
  3. Activity Length
  4. NIBLSE Core Competencies
  5. NIBLSE Status
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Description

From the abstract:

Constructing a robust understanding of homologous chromosomes, sex chromosomes, and the particulate nature of genes is a notoriously difficult task for undergraduate biology students. In this lesson, students expand their knowledge of human chromosome pairs by closely examining autosomes, sex chromosomes, and the non-homologous elements of the human X and Y sex chromosomes. In this four- part guided activity, students will learn about the structure and function of human autosomal and sex chromosomes, view and interpret gene maps, and gain familiarity with basic bioinformatics resources and data through use of the National Center for Biotechnology Information (NCBI) website. (Student access to computers with Internet connectivity is required for the completion of all Investigations within this lesson.) 

Citation:

Metzger, K.J. 2014. Homologous chromosomes? Exploring human sex chromosomes, sex determination and sex reversal using bioinformatics approaches. CourseSource. https://doi.org/10.24918/cs.2014.5

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