The Ames Test
Author(s): Nathan Goodson-Gregg, Elizabeth A. De Stasio
475 total view(s), 103 download(s)
Description
This published laboratory introduces students to the Ames test, an assay used to determine the mutagenic properties of chemical compounds, using a distinctly quantitative approach. Students must develop their own hypotheses, use proper positive and negative controls, perform their own serial dilutions, use sequencing and bioinformatics to assess their results, and finally, write up their findings in a formal laboratory report.
Citation:
Goodson-Gregg, N. and De Stasio, E. A. (2009) Reinventing the Ames Test as a Quantitative Lab That Connects Classical and Molecular Genetics. Genetics 181: 23-21. DOI: 10.1534/genetics.108.095588
Notes
This version has an updated link to the content.
Cite this work
Researchers should cite this work as follows:
- Nathan Goodson-Gregg, Elizabeth A. De Stasio (2021). The Ames Test. Network for Integrating Bioinformatics into Life Sciences Education, (Version 2.0). QUBES Educational Resources. doi:10.25334/P18R-F263