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Colon Cancer: A Case of Genetic Bad Luck

By Anne M. Casper

Eastern Michigan University

Case study developed for an introductory genetics class published in the National Center for Case Study Teaching in Science

Listed in Teaching Materials | resource by group Network for Integrating Bioinformatics into Life Sciences Education

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Version 1.0 - published on 03 Jan 2019 doi:10.25334/Q4WT7B - cite this

Licensed under these terms

colon_cancer_case.png

Description

In this case, developed for an introductory genetics class, students meet a woman whose family has a history of colon cancer. Students create a pedigree based on information from the case and discuss what it means to be genetically predisposed to cancer. Using bioinformatics tools from the NCBI database, students identify and examine the mutation in the woman’s APC gene that results in genetic predisposition to colon cancer.

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Network for Integrating Bioinformatics into Life Sciences Education

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