The Galleria mellonella; the larvae of the Greater Wax Moth, is a safe and effective means to study host-pathogen interactions in the undergraduate setting. The use of animal models in the teaching classroom provides an opportunity to discuss proper animal use and the benefits of alternative model systems in research. In this lesson, we developed a laboratory experience for students to learn about the use of G. mellonella as a model to study bacterial virulence. Students evaluate the virulence o…