CourseSource: Resources

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Using Yeast to Make Scientists: A Six-Week Student-Driven Research Project for the Cell Biology Laboratory

Traditionally-trained undergraduate students often lack an understanding of science as an active process that yields the information presented in their textbooks. One result has been a call for more research experiences built into traditional...

Courses: Cell Biology Science Process Skills

yeastgrowth curvecell proliferationviability

Lesson

4334

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1659

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Teaching Genetic Linkage and Recombination through Mapping with Molecular Markers

Most introductory genetics courses cover genetic linkage, a core concept in the CourseSource genetics learning outcome framework. Although it is a classical genetics topic, genetic linkage remains an important concept to understand in order to...

Courses: Genetics Plant Biology Science Process Skills

meiosisphenotypegel electrophoresismicrosatellitesBanding PatternGenetic linkageInheritanceMolecular MarkersPhysical Linkage

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1029

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146

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Fatty Acid Induction of Lipid Droplets in Cancer Cells

There is a growing need for the development and communication of cell culture-based laboratory activities specifically designed for undergraduate students. This multi-week laboratory activity allows students to take part in the planning,...

Courses: Cell Biology Science Process Skills

Course based undergraduate researchCell ImagingLive Cell Staining

Lesson

1679

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308

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Engaging Students in Pharmacogenetics: Patient Case Studies Using the PharmGKB Website

Cytochrome P450 (CYP) enzymes are important regulators of drug efficacy and toxicity. Genetic variation in CYP isoforms can impact how well patients respond to medications or experience unwanted toxicities. PharmGKB is an online pharmacogenomics...

Courses: Genetics Toxicology

toxicologyPharmacologydrug metabolismpharmacodynamicspharmacogenetics

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2307

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167

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Online Information Literacy: Applying the CRAAP Test to Vaccine (Mis)information

Teaching scientific literacy skills can help combat the propagation of misinformation online. This lesson is intended to give students practice identifying reliable scientific information on the Internet, in the context of vaccine safety. It was...

Courses: Science Process Skills

Vaccinesimmunityreliability

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2367

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440

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Exploring Miracle Fruit: An Undergraduate Laboratory Exercise on Experimental Design

In recent years, undergraduate biology and biochemistry curricula have seen an increase in the use of course-based undergraduate research experiences (CUREs). CUREs maximize potential student gains when students take an active role in experimental...

Courses: Biochemistry and Molecular Biology Science Process Skills

sensory systemspHProtein shapeTaste

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Single Cell Insights Into Cancer Transcriptomes: A Five-Part Single-Cell RNAseq Case Study Lesson

There is a growing need for integration of “Big Data” into undergraduate biology curricula. Transcriptomics is one venue to examine biology from an informatics perspective. RNA sequencing has largely replaced the use of microarrays for whole...

Courses: Biochemistry and Molecular Biology Bioinformatics Cell Biology Genetics Introductory Biology

bioinformaticscancertranscriptomicshigh-throughputData wranglingSingle cell RNA sequencingq

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2750

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509

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A Fun Introductory Command Line Lesson: Next Generation Sequencing Quality Analysis with Emoji!

Radical innovations in DNA sequencing technology over the past decade have created an increased need for computational bioinformatics analyses in the 21st century STEM workforce. Recent evidence however demonstrates that there are significant...

Courses: Bioinformatics

bioinformaticsgenomicscodingJupyter notebookcommand lineCyVersescriptingnext generation sequencing analysis

Lesson

4920

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2371

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Exploring the Lytic and Lysogenic Life Cycles of Bacteriophages

The goal of this lesson is to introduce students to the lytic and lysogenic cycles of T4 and lambda bacteriophages, respectively, using student-centered pedagogies. Bacteriophages are viruses that infect bacteria and are either virulent or...

Courses: Microbiology

bacteriophagesLysogenic cycleLysogenyLytic cycle

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1605

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451

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Ain't No Mountain Pine Enough: A Case Study of How Mountain Pine Beetles are Affecting Ecosystem Processes

This case study engages students in generating hypotheses and predictions, analyzing and interpreting data, critically evaluating contrasting results in science, and thinking about feedbacks between biota and abiotic ecosystem dynamics. To address...

Courses: Ecology Ecology

population biologycarbon cyclingSpecies-habitat interactions

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2519

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473

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Harnessing the Power of the Immune System: Influenza Vaccines

Because most people have been infected by and/or immunized against influenza, students should know how the immune system responds to the infection and how vaccines protect against disease. Vaccines have played an instrumental role in disease...

Courses: Biochemistry and Molecular Biology Immunology Science Process Skills

VaccinesInfluenzaImmunizationVaccine efficacy

Lesson

2046

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457

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A Lesson on Matter and Energy at the Organismal Scale: Linking Patterns and Processes Across Diverse Taxa

Pathways and transformations of energy and matter (PTEM) are a conceptually challenging but essential component of biological literacy. Curricular gaps about PTEM nevertheless remain; although lessons targeting PTEM at small scales (chemical,...

Courses: Ecology Ecology Introductory Biology

plantsenergyAnimalsfungimatterorganismal scale

Lesson

1252

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296

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Using Seafood Traceability to Teach the Complexities of Natural Resource Management and Sustainability

This lesson plan addresses the challenge of conveying to students the globalized nature and complexity of natural resource management. Specifically, it uses seafood traceability, or the ability to track seafood as it moves through the global...

Courses: Ecology Ecology

sustainabilityfisheriesaquacultureAnthropogenic ImpactsNatural Resource Management

Teaching Tools and Strategies

2045

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326

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DNA Detective: Genotype to Phenotype. A Bioinformatics Workshop for Middle School to College.

Advances in high-throughput techniques have resulted in a rising demand for scientists with basic bioinformatics skills as well as workshops and curricula that teach students bioinformatics concepts. DNA Detective is a workshop we designed to...

Courses: Biochemistry and Molecular Biology Bioinformatics Genetics Plant Biology

geneticsbioinformaticsDNAgenotypephenotypegenegene annotation

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1779

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308

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Modeling the Research Process: Authentic human physiology research in a large non-majors course

Laboratory experiences in large-enrollment introductory science courses often utilize “cookie-cutter style” laboratory experiences due to the relative simplicity of setting up the lab stations, as well as a need to teach students...

Courses: Anatomy-Physiology Introductory Biology Neurobiology Science Process Skills

data analysishypothesis testingexperimental designphysiology

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643

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24

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Learning the Landscape: An Active and Applied Lesson on Landscape Ecology for General Ecology Courses

Landscape ecology is an important subtopic of ecology. As a field, it is inherently interdisciplinary and provides opportunities to teach not only content, but transferable ecological and geographical skills. Given the broad spectrum of topics in...

Courses: Ecology Ecology

landscape ecologyspatial scaleecosystem managementHabitat fragmentation

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2040

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209

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Diversifying and Humanizing Scientist Role Models Through Interviews and Constructing Slide Decks on Researchers’ Research and Life Experiences

To maintain recruitment and retention, biology teachers face the challenge of finding relatable role models for their students. Our ever-increasing scientific knowledge has been facilitated by people from many different backgrounds, identities,...

Courses: Professional Development and Career Planning Science Process Skills

researchdiversityinclusionScientific ProcessRepresentationScientistRole Models

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Using Zebrafish in a Developmental Biology Lab Course to Explore Interactions Between Development and the Environment

Important learning outcomes for biology students include the ability to develop experiments as well as pull together concepts across their coursework. The field of developmental biology, especially environmental influences on development...

Courses: Developmental Biology Science Process Skills

toxicologymorphogenesisorganogenesis

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Using Yeast to Make Scientists: A Six-Week Student-Driven Research Project for the Cell Biology Laboratory

Teaching Genetic Linkage and Recombination through Mapping with Molecular Markers

Fatty Acid Induction of Lipid Droplets in Cancer Cells

Engaging Students in Pharmacogenetics: Patient Case Studies Using the PharmGKB Website

Online Information Literacy: Applying the CRAAP Test to Vaccine (Mis)information

Exploring Miracle Fruit: An Undergraduate Laboratory Exercise on Experimental Design

Single Cell Insights Into Cancer Transcriptomes: A Five-Part Single-Cell RNAseq Case Study Lesson

A Fun Introductory Command Line Lesson: Next Generation Sequencing Quality Analysis with Emoji!

Exploring the Lytic and Lysogenic Life Cycles of Bacteriophages

Ain't No Mountain Pine Enough: A Case Study of How Mountain Pine Beetles are Affecting Ecosystem Processes

Harnessing the Power of the Immune System: Influenza Vaccines

A Lesson on Matter and Energy at the Organismal Scale: Linking Patterns and Processes Across Diverse Taxa

Using Seafood Traceability to Teach the Complexities of Natural Resource Management and Sustainability

DNA Detective: Genotype to Phenotype. A Bioinformatics Workshop for Middle School to College.

Modeling the Research Process: Authentic human physiology research in a large non-majors course

Learning the Landscape: An Active and Applied Lesson on Landscape Ecology for General Ecology Courses

Diversifying and Humanizing Scientist Role Models Through Interviews and Constructing Slide Decks on Researchers’ Research and Life Experiences

Using Zebrafish in a Developmental Biology Lab Course to Explore Interactions Between Development and the Environment

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