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    Investigating the Function of a Transport Protein: Where is ABCB6 Located in Human Cells?
    One of the challenges of teaching Cell Biology is helping students understand important research methods used to study cells.  The goal of understanding cell biology methods is especially challenging in courses without a laboratory...

    Courses: Cell BiologyCell Biology

    ABC transporter familyDifferential centrifugationImmunoblottingImmunofluorescence assayProtein localizationPurifying organellesSDS-PAGE
    Lesson
    2422

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    550

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    Linking Genotype to Phenotype: The Effect of a Mutation in Gibberellic Acid Production on Plant Germination
    Basic concepts in genetics and plant development are often taught in lecture courses without a lab component. This approach provides students with the content knowledge, but fails to make connections to research opportunities and real-world...

    Courses: Cell BiologyCell Biology Developmental BiologyDevelopmental Biology GeneticsGenetics Introductory BiologyIntroductory Biology Plant BiologyPlant Biology

    geneticsdevelopmentmutationgerminationplantmodel organismGenotype/PhenotypeHormoneSeed
    Lesson
    2612

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    983

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    Building Trees: Introducing evolutionary concepts by exploring Crassulaceae phylogeny and biogeography
    Teaching evolutionary theory is foundational for all biological sciences and a key aspect of overall science literacy. The conceptual framework for understanding evolution relies on thinking clearly about evolutionary trees (phylogenetics) and how...

    Courses: EvolutionEvolution Introductory BiologyIntroductory Biology

    EvolutionphylogeneticsTree thinkingbiogeography
    Lesson
    3707

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    1233

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    Evaluating the Quick Fix: Weight Loss Drugs and Cellular Respiration
    One key to student success in introductory and cell biology courses is a foundational knowledge of cellular respiration. This is a content area in which students often harbor misconceptions that make cellular respiration particularly challenging...

    Courses: Biochemistry and Molecular BiologyBiochemistry and Molecular Biology Cell BiologyCell Biology Introductory BiologyIntroductory Biology

    data analysisCellular RespirationElectron Transport ChainEnergy transformationsMitochondriaOxidative phosphorylationWeight loss drugs24-dinitrophenol (DNP)
    Teaching Tools and Strategies
    916

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    120

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    Casting a Wide Net via Case Studies: Educating across the undergraduate to medical school continuum in the biological sciences
    This article seeks to help bridge undergraduate and medical educators by describing shared educational goals and strategies, highlighting resources relevant for both groups, and exemplifying shared interests through a demonstration resource. Both...

    Courses: GeneticsGenetics

    genetic testingdirect-to-consumer genetic testinginformed consentprenatal screeningsecondary findingswhole genome sequencing
    Lesson
    2693

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    323

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    Serotonin in the Pocket: Non-covalent interactions and neurotransmitter binding
    This lesson introduces beginning biochemistry students to the concept of a biomolecule binding site, such as a neurotransmitter receptor site or an enzyme active site. A simple organic molecule, the neurotransmitter serotonin, is the focus of the...

    Courses: Biochemistry and Molecular BiologyBiochemistry and Molecular Biology

    active sitebindingbinding sitehydrogen bondinghydrophobic effectionic interactionsnon-covalent forces
    Lesson
    4243

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    650

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    A simple way for students to visualize cellular respiration: adapting the board game MousetrapTM to model complexity
    Lecture-based introductory biology courses are typically content-heavy as instructors strive to provide students with foundational knowledge in a broad range of topics.  One topic traditionally covered is cellular respiration, the series of...

    Courses: Introductory BiologyIntroductory Biology

    ATPGlycolysisCellular RespirationElectron Transport ChainKrebs Cycle
    Lesson
    5308

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    1058

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    2

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    Meiosis: A Play in Three Acts, Starring DNA Sequence
    Meiosis is well known for being a sticky topic that appears repeatedly in biology curricula. We observe that a typical undergraduate biology major cannot correctly identify haploid and diploid cells or explain how and why chromosomes pair before...

    Courses: Cell BiologyCell Biology GeneticsGenetics Introductory BiologyIntroductory Biology

    recombinationmeiosisDNA sequenceCrossingoverchromosome structureHolliday junctionhomology
    Lesson
    2731

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    329

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    Discovering Cellular Respiration with Computational Modeling and Simulations
    Cellular respiration, a common topic among introductory and cellular biology curricula, is a complex biological process that exemplifies core biological concepts, including systems, pathways and transformation of energy, and structure and function...

    Courses: Introductory BiologyIntroductory Biology

    Cellular MechanismsCellular RespirationFermentation
    Lesson
    4702

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    931

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    An active-learning lesson that targets student understanding of population growth in ecology
    Effective teaching and learning of population ecology requires integration of quantitative literacy skills. To facilitate student learning in population ecology and provide students with the opportunity to develop and apply quantitative skills, we...

    Courses: EcologyEcology Introductory BiologyIntroductory Biology

    population growthexponential growthlogistic growthpopulation ecologygrowth rateDensityAbundancecarrying capacitylinear growth
    Lesson
    1366

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    282

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    Promoting Climate Change Literacy for Non-majors: Implementation of an atmospheric carbon dioxide modeling activity as an inquiry-based classroom activity
    Students who are directly involved in scientific activities develop a deeper understanding and appreciation of both scientific knowledge and the scientific process. This understanding is critically important in scientific areas like climate change...

    Courses: Introductory BiologyIntroductory Biology Science Process SkillsScience Process Skills

    modelingExcelquantitativeclimate changeEnvironmental Biologyatmospheric carbon dioxide
    Lesson
    1386

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    284

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    Using QIIME to Interpret Environmental Microbial Communities in an Upper Level Metagenomics Course
    Metagenomics is rapidly evolving due to advances in sequencing technologies and bioinformatics, but without proper training to interpret these datasets, student understanding remains limited. Aimed at undergraduate juniors and seniors and graduate...

    Courses: Biochemistry and Molecular BiologyBiochemistry and Molecular Biology BioinformaticsBioinformatics EcologyEcology MicrobiologyMicrobiology Science Process SkillsScience Process Skills

    microbiome
    Lesson
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    210

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    A new approach to course-based research using a hermit crab-hydrozoan symbiosis
    There are few feasible models for marine-focused inquiry laboratory activities, a notable shortcoming for instructors seeking to engage their students in meaningful, course-based research experiences (CUREs). We describe a multi-week CURE that...

    Courses: EcologyEcology EvolutionEvolution Introductory BiologyIntroductory Biology Science Process SkillsScience Process Skills

    behaviorparasitismSymbiosismutualismcommensalism
    Teaching Tools and Strategies
    911

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    97

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    In-class peer grading of daily quizzes increases feedback opportunities
    Educators are familiar with evidence of the benefit that frequent and immediate feedback provides to our students, regardless of class size. We also often find ourselves in a situation where we do not have enough time planned or TA support...

    Courses: Introductory BiologyIntroductory Biology

    foundational knowledgegraphical interpretationtechnical terms
    Lesson
    4090

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    716

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    Using Yeast to Make Scientists: A Six-Week Student-Driven Research Project for the Cell Biology Laboratory
    Traditionally-trained undergraduate students often lack an understanding of science as an active process that yields the information presented in their textbooks. One result has been a call for more research experiences built into traditional...

    Courses: Cell BiologyCell Biology Science Process SkillsScience Process Skills

    yeastgrowth curvecell proliferationviability
    Lesson
    5182

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    879

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    A clicker-based case study that untangles student thinking about the processes in the central dogma
    The central dogma of biology is a foundational concept that provides a scaffold to understand how genetic information flows in biological systems. Despite its importance, undergraduate students often poorly understand central dogma processes (DNA...

    Courses: GeneticsGenetics Introductory BiologyIntroductory Biology

    mutationtranscriptionphenotypecentral dogmatranslationDNA replication
    Lesson
    2000

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    410

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    Antibiotic Resistance Genes Detection in Environmental Samples
    Our aim is to provide an authentic research experience for undergraduate students in a variety of biology courses through collaboration between a four-year university and a community college. This lab series teaches transferable and universal...

    Courses: Introductory BiologyIntroductory Biology MicrobiologyMicrobiology Science Process SkillsScience Process Skills

    geneticsenvironmentmicrobiologyUndergraduateantibiotic-resistancePCRgel electrophoresisauthentic inquiry
    Lesson
    3236

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    503

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    Knowing your own: A classroom case study using the scientific method to investigate how birds learn to recognize their offspring
    Understanding the scientific method provides students with a necessary foundation for careers in science-related fields. Moreover, students can apply scientific inquiry skills in many aspects of their daily lives and decision making. Thus, the...

    Courses: EvolutionEvolution Introductory BiologyIntroductory Biology Science Process SkillsScience Process Skills

    scientific methodNatural Selectionbrood parasitism
    Teaching Tools and Strategies
    1844

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    298

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    "Reading groups" in an undergraduate biology course: A peer-based model to help students develop skills to evaluate primary literature
    Undergraduates who learn to evaluate primary literature demonstrate an enhanced ability to understand the process of science, weigh scientific evidence, and think critically (e.g. 6,8). Studies show that students who learn how to dissect primary...

    Courses: Biochemistry and Molecular BiologyBiochemistry and Molecular Biology Science Process SkillsScience Process Skills

    primary literaturecritical thinkingSelf-EfficacyDiscussionPeer-based Learning
    Lesson
    1333

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    463

    downloads

    1

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    Grow the Gradient: An interactive countercurrent multiplier game
    The countercurrent multiplier of the loop of Henle in a mammalian kidney is a challenging concept for instructors to teach and for students to learn. We developed an interactive game to support student learning of this dynamic process with a team...

    Courses: Anatomy-PhysiologyAnatomy-Physiology Introductory BiologyIntroductory Biology

    countercurrent multiplierexcretory systemkidneyloop of Henlemembrane transport