CourseSource: Resources

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A first lesson in mathematical modeling for biologists: Rocs

Using a fictitious population of Rocs, a mythical species of giant raptor, students accomplish two broad objectives: 1) they undertake the process of building a first mathematical model of a population, and 2) they begin to develop their...

Courses: Ecology Ecology Introductory Biology Science Process Skills

population ecologypopulation modelingdiscrete generationpopulation management

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3579

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505

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How Many Squirrels Are in the Shrubs? A Lesson Plan for Comparing Methods for Population Estimation

Estimating the population sizes of animals is a key skill for any student interested in ecology, conservation, or management. However, counting animals in natural habitats is difficult, and the many techniques that exist each rely on assumptions...

Courses: Ecology Ecology Introductory Biology Professional Development and Career Planning Science Process Skills

population ecologywildlife managementpopulation estimationsciuridaeSquirrel-Net

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3073

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453

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Moths and Frogs and E. coli, Oh My!: Agent-based Modeling of Evolutionary Systems

In evolution classrooms, introducing and reinforcing the idea of genetic drift and random selection can be challenging, as can be reinforcing appropriate mental models of evolution. Agent-based models offer students the opportunity to conduct a...

Courses: Bioinformatics Ecology Ecology Evolution Science Process Skills

modelingEvolutionecologyagent-based modelingGenetic Driftenvironmental scienceNatural Selectioncompetitive coevolutionsimulation modelingevolutionary reasoning

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2984

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942

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Coevolution or not? Crossbills, squirrels and pinecones

This case reinforces the concept of coevolution as a reciprocal change in genetic structure between or among two or more populations, by having students analyze and interpret data, build a descriptive model of the system, and use data to make...

Courses: Ecology Ecology Evolution Introductory Biology Science Process Skills

fitnessCoevolutionCo-adaptation

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1793

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342

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Cutthroat trout in Colorado: A case study connecting evolution and conservation

Evaluation of evidence is a key process skill for the core competencies of applying the process of science and using quantitative reasoning. This case study enables upper-division biology students to practice these skills by applying evolutionary...

Courses: Evolution Genetics Science Process Skills

population geneticsphylogeneticsSpeciationdivergencegene flow

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2046

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586

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BioVEDA Curriculum: An Approach to Link Conceptual and Quantitative Understanding of Variation During Experimental Design and Data Analysis

When performing a biological investigation, experts constantly cycle between conceptual and quantitative modes of thinking, integrating their understanding in both worlds to make decisions about their work. This cycling and mixing of conceptual...

Courses: Science Process Skills

statisticssample sizeBiological variation

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6519

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1118

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Mapping a Mutation to its Gene: The "Fly Lab" as a Modern Research Experience

Although genetics is an invaluable part of the undergraduate biology curriculum, it can be intimidating to students as well as instructors: Students must reduce their reliance on memorization and dive deep into quantitative analysis, and...

Courses: Biochemistry and Molecular Biology Bioinformatics Genetics Science Process Skills

geneticsbioinformaticsdrosophilachi-square analysiscomplementation mappingmode of inheritancethree-point mapping

Teaching Tools and Strategies

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1718

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A 360˚ View of COVID-19

In March 2020, institutions underwent a massive transition to distance learning as a result of the COVID-19 pandemic. With so little time to devise new materials to maximize learning in the new virtual environment, instructors devised a variety of...

Courses: Biochemistry and Molecular Biology Bioinformatics Cell Biology Evolution Genetics Immunology Introductory Biology Microbiology Science Process Skills

geneticsImmunologyBiochemistrybioinformaticsmolecular evolutionpublic healthvirusCOVID19

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1903

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474

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Why do Some People Inherit a Predisposition to Cancer? A small group activity on cancer genetics

Before undergraduate students take a genetics course they generally know cancer has a genetic basis and involves the proliferation of cells; however, many are uncertain about why only a subset of people have a predisposition to cancer and how that...

Courses: Genetics Science Process Skills

cancerInheritance patternsProbability calculationProto-oncogeneTumor Suppressor Gene

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4857

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1858

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Teaching Genetic Linkage and Recombination through Mapping with Molecular Markers

Most introductory genetics courses cover genetic linkage, a core concept in the CourseSource genetics learning outcome framework. Although it is a classical genetics topic, genetic linkage remains an important concept to understand in order to...

Courses: Genetics Plant Biology Science Process Skills

meiosisphenotypegel electrophoresismicrosatellitesBanding PatternGenetic linkageInheritanceMolecular MarkersPhysical Linkage

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3164

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1094

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Squirreling Around for Science: Observing Sciurid Rodents to Investigate Animal Behavior

Hands-on research experiences are important opportunities for students to learn about the nature of inquiry and gain confidence in solving problems. Here, we present an inquiry-based lesson plan that investigates the foraging behavior of sciurid...

Courses: Ecology Ecology Introductory Biology Science Process Skills

foragingbehaviorbehavioral ecologySciuridSquirrelSquirrel-NetTrade-offVigilance

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5095

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348

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Learning to Pipet Correctly by Pipetting Incorrectly?

Beginning undergraduate students in biology need basic laboratory, data analysis, and science process skills to pursue more complex questions in course-based undergraduate research experiences (CUREs). To this end, we designed an introductory...

Courses: Introductory Biology Science Process Skills

statisticslaboratorypipetting

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2260

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480

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Air Quality Data Mining: Mining the US EPA AirData website for student-led evaluation of air quality issues

Air pollution directly affects human health endpoints including growth, respiratory processes, cardiovascular health, fertility, pregnancy outcomes, and cancer. Therefore, the distribution of air pollution is a topic that is relevant to all, and...

Courses: Ecology Ecology Introductory Biology Science Process Skills

data miningenvironmental justiceair qualityairpollutionspatial reasoning

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1691

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494

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Sex-specific differences in Meiosis: Real-world applications

In traditional classrooms, students are typically presented with facts that they are asked to memorize and recall during an exam. The rapid explosion of available scientific facts in recent years has made this model of teaching...

Courses: Cell Biology Genetics Science Process Skills

meiosisReproductionAneuploidyGameteNon-disjunctionOocyteSpermTrisomy

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158

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Infectious Chocolate Joy with a Side of Poissonian Statistics: An activity connecting life science students with subtle physics concepts

Introductory physics courses are required for many programs in the life sciences, yet traditional curricula fail to help students meaningfully connect physical concepts with biological systems. In this lesson, we describe an activity taught...

Courses: Bioinformatics Microbiology Science Process Skills

quantitative biologyHIVmultiplicity of infectionPoisson DistributionPhysics for biologists

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A virtual laboratory on cell division using a publicly-available image database

Cell division is a key concept in cell biology. While there are many popular activities to teach students the stages of mitosis, most make use of simple schematics, cartoons, or textbook diagrams. Others engage students in acting out the stages,...

Courses: Cell Biology Science Process Skills

image analysismicroscopymitosisCellular Processes

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A new approach to course-based research using a hermit crab-hydrozoan symbiosis

There are few feasible models for marine-focused inquiry laboratory activities, a notable shortcoming for instructors seeking to engage their students in meaningful, course-based research experiences (CUREs). We describe a multi-week CURE that...

Courses: Ecology Ecology Evolution Introductory Biology Science Process Skills

behaviorparasitismSymbiosismutualismcommensalism

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1578

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350

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Understanding Protein Domains: A Modular Approach

An understanding of protein structure, function, and interaction is central to biochemistry. One angle into this topic is to engage students in considering protein domains as modules that develop form and execute function semi-independently. Here,...

Courses: Biochemistry and Molecular Biology Cell Biology Science Process Skills

Protein Structure

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Nanoparticles and Shrimp: An Interdisciplinary Lab Series in Chemistry and Biology for Undergraduate Engineering Students

The parallels between engineering and science are vast, as both disciplines apply theory and inquiry to solve complex problems. In order to prepare students for interdisciplinary careers in STEM, we have developed a lab project in which...

Courses: Cell Biology Ecology Ecology Science Process Skills

microscopychemistry applications in biologytoxicity

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750

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Using Zebrafish in a Developmental Biology Lab Course to Explore Interactions Between Development and the Environment

Important learning outcomes for biology students include the ability to develop experiments as well as pull together concepts across their coursework. The field of developmental biology, especially environmental influences on development...

Courses: Developmental Biology Science Process Skills

toxicologymorphogenesisorganogenesis

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A first lesson in mathematical modeling for biologists: Rocs

How Many Squirrels Are in the Shrubs? A Lesson Plan for Comparing Methods for Population Estimation

Moths and Frogs and E. coli, Oh My!: Agent-based Modeling of Evolutionary Systems

Coevolution or not? Crossbills, squirrels and pinecones

Cutthroat trout in Colorado: A case study connecting evolution and conservation

BioVEDA Curriculum: An Approach to Link Conceptual and Quantitative Understanding of Variation During Experimental Design and Data Analysis

Mapping a Mutation to its Gene: The "Fly Lab" as a Modern Research Experience

A 360˚ View of COVID-19

Why do Some People Inherit a Predisposition to Cancer? A small group activity on cancer genetics

Teaching Genetic Linkage and Recombination through Mapping with Molecular Markers

Squirreling Around for Science: Observing Sciurid Rodents to Investigate Animal Behavior

Learning to Pipet Correctly by Pipetting Incorrectly?

Air Quality Data Mining: Mining the US EPA AirData website for student-led evaluation of air quality issues

Sex-specific differences in Meiosis: Real-world applications

Infectious Chocolate Joy with a Side of Poissonian Statistics: An activity connecting life science students with subtle physics concepts

A virtual laboratory on cell division using a publicly-available image database

A new approach to course-based research using a hermit crab-hydrozoan symbiosis

Understanding Protein Domains: A Modular Approach

Nanoparticles and Shrimp: An Interdisciplinary Lab Series in Chemistry and Biology for Undergraduate Engineering Students

Using Zebrafish in a Developmental Biology Lab Course to Explore Interactions Between Development and the Environment

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